PřF:C7016 Nucleic acids chemistry

C7016 Chemical properties, structure and interactions of nucleic acids

Faculty of Science
Autumn 1999

Extent and Intensity

3/1/0. 4 credit(s). Type of Completion: k (colloquium).

Teacher(s)

prof. RNDr. Emil Paleček, DrSc. (lecturer)

Guaranteed by

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 17 fields of study the course is directly associated with, display

Syllabus

Introduction. Nucleic acids - history. DNA double helix. Isolation and characterisation of nucleic acids. Physical properties of DNA and DNA conformation. Supercoil-stabilised local DNA structures. Nucleases, topoisomerases, helicases, ligases. Covalent interactions of Nas with small molecules. Reversible interactions of small molecules with DNA. Structure of RNA. Methods of nucleic acids analysis. Gene therapy. Oligonucleotides and their analogues. DNA-protein interactions. DNA structure and interactions in biomedicine. Protein p53 and its interactions with DNA.

Language of instruction

Czech

Further Comments

The course is taught annually.
The course is taught: every week.

The course is also listed under the following terms autumn 2021, Autumn 2022, Autumn 2023, Autumn 2024.