Bi7790 Imunology

Faculty of Science
Autumn 2002
Extent and Intensity
3/0/0. 3 credit(s) (fasci plus compl plus > 4). Type of Completion: graded credit.
Teacher(s)
doc. RNDr. Alena Žákovská, Ph.D. (lecturer)
Guaranteed by
doc. RNDr. Alena Žákovská, Ph.D.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: doc. RNDr. Alena Žákovská, Ph.D.
Prerequisites
Lecture involves the following program: 1.Immune system: 2.Cells and organs of the immunity 3.Immune response: antigens, structure, chemical properties, clasification, presentation MHC structure, function, regulation, immunogenetic: genes displacement, polymorphism, genesis of diversity Antibodies: structure, chemical properties, functions, classes of antibodies, isotypes, allotypes, idiotypes Nonspecific immunity: complemet: structure and function, accute phasis reactans, inflammation Phagocytosis: phases, cooperation of the phagocytosis with other components of the immune system 4.The mechanism of the hypersensitivity: 5.Cytokine and immunomodulators: 6.Immunoregulation: 7.Immunology of transplantation 8. Immunity and cancer 9. Immunotoxicology 10. Reactions of the antigens and antibodies
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Syllabus 1.Immune system: 2.Cells and organs of the immunity - ontogenesis, phenotype, structure, function and activacion, signs receptors: 3.Immune response: antigens, structure, chemical properties, clasification, presentation MHC structure, function, regulation, immunogenetic: genes displacement, polymorphism, genesis of diversity Antibodies: structure, chemical properties, functions, classes of antibodies, isotypes, allotypes, idiotypes T-cell receptors: structure, function and antigen binding, interaction of receptors with ligands: adhesive molecules, complement receptors, Fc receptors, transfer of signals Nonspecific immunity: complemet: structure and function, accute phasis reactans, inflammation Phagocytosis: phases, cooperation of the phagocytosis with other components of the immune system 4.The mechanism of the hypersensitivity: IgE mediated : early and late response IgG, IgA and IgM : mediated, opsonisation, complement binding Immune complexes: mediated Cells mediated: Others NK cells, killer cells after the lymphokine activation, skin basophile hypersensitivity 5.Cytokine and immunomodulators: cytokine : origin, structure, effect, receptor-place of effect, metabolism, regulation and gene activation inflammation regulators: origin, structure, effect, receptor-place of effect, metabolism and regulation 6.Immunoregulation: Toleration, clonal selection, inhibition, antigenic paralytic. Intracellular - interaction: help and inhibition (suprese) Idiotype network: inhibition and simulation Mechanism of auto-immunity 7.Immunology of transplantation 8. Immunity and cancer 9. Immunotoxicology 10. Reactions of the antigens and antibodies
Language of instruction
Czech
Further Comments
The course can also be completed outside the examination period.
The course is taught annually.
The course is taught: every week.
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