Bi7140 Molecular biology of viruses

Faculty of Science
Autumn 2004
Extent and Intensity
2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
Teacher(s)
doc. RNDr. Vladislava Růžičková, CSc. (lecturer)
Guaranteed by
doc. RNDr. Vladislava Růžičková, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: doc. RNDr. Vladislava Růžičková, CSc.
Timetable
Wed 13:00–14:50 B1,01004
Prerequisites
B4030 Molecular biology || B5740 Molecular biology || B6130 Molecular biology || B7940 Molecular biology || B4020 Molecular biology || Bi4020 Molecular biology
1.Molecular structure reproduction a function of procaryotic and eucaryotic genome. 2. Basic methods in molecular biology 3. Molecular foundation of acquired immunity. Molecular foundation of cancerogenesis.
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Molecular biology and genetics of bacterial viruses contains morphology and structure of bacterial viruses, infection and lysis of bacterial cells caused by phage virions, adsorption of phage virion to the surface of bacterial cells, synthesis of bacterial viruses in host cell, mutation and recombination of bacteriophage, lysogeny and genetics of temperate phage, general characteristics of some temperate phages. Molecular biology and genetics of vertebrate and invertebrate viruses: papovaviruses, adenoviruses, herpesviruses, poxviruses, parvoviruses, reoviruses, flaviviruses, picornaviruses, togaviruses, arteriviruses, rhabdoviruses, paramyxoviruses, filoviruses, orthomyxoviruses, bunyaviruses, retroviruses, hepadnaviruses. Molecular biology of retroviruses including the virus HIV and HTLV, adenoviruses, herpesviruses, influenzavirus, hepadnaviruses and oncoviruses are given in detail. Molecular biology and genetics of plant viruses: caulimoviruses, geminiviruses, bromoviruses, nepoviruses, tymoviruses, tobamoviruses, tombusviruses, luteoviruses, hordeiviruses, potexviruses etc. Characteristics of main types of plant diseases caused by viruses are explained. Molecular taxonomy and evolution of viruses. Molecular diagnostic of viruses. Prions and viriods. Virus cloning vectors.
Syllabus
  • 1. Molecular characterisation of live noncellular systems, termines a definition explaining the nature molecular biology of viruses 2. Properties of viruses having importance in their molecular classification 3. Life cycle of viruses and the types of viral infections in host organisms, molecular mechnisms of viral persistence and latency 4. Molecular characteristic of viruses of procarytes 5. Molecular characteristic of viruses of ecaryotes i.e. vertebrates, invertebrates, and plants. 6. Molecular characteristic of oncoviruses 7. Molecular basis of occurence of transmissible encephalopathy (TSE) 8. Molecular diagnostics and evolution of viruses.
Literature
  • Přehled literatury je dostupný u vyučujícího
  • ROSYPAL, Stanislav. Úvod do molekulární biologie. Díl druhý, (Makromolekulární biologie eukaryot). 3. inovované vyd. Brno: Stanislav Rosypal, 1999, s. 304-600. ISBN 80-902562-1-X. info
  • Špeciálna virológia. Edited by Jaroslav Žemla - Fedor Čiampor - Milan Labuda. 1. vyd. Bratislava: Slovac Academic Press, 1998, 226 s., č. ISBN 80-88908-04-3. info
  • TIMBURY, Morag C. Notes on medical virology. 11th ed. New York: Churchill Livingstone, 1997, 196 s. ISBN 0-443-05846-6. info
  • ROSYPAL, Stanislav. Úvod do molekulární biologie : dodatek. 2. rozš. vyd. Brno: Stanislav Rosypal, 1997, 996 s. info
  • Všeobecná virológia. Edited by Jaroslav Žemla - Fedor Čiampor - Jozef Leššo. 1. vyd. Bratislava: Slovac Academic Press, 1995, 238 s., il. ISBN 80-85665-47-6. info
  • LEVY, Jay A., Heinz FRAENKEL-CONRAT and Robert A. OWENS. Virology. 3rd ed. Englewood Cliffs: Prentice-Hall, 1994, xii, 447 s. ISBN 0-13-953753-8. info
  • CANN, Alan J. Principles of molecular virology. London: Academic Press, 1993, 234 s. ISBN 0-12-158531-X. info
Assessment methods (in Czech)
Výuka: přednáška, Zkouška: písemná: testové otázky, grafika, výpočty, doplňování a odpovědi.
Language of instruction
Czech
Follow-Up Courses
Further comments (probably available only in Czech)
The course can also be completed outside the examination period.
The course is taught annually.
Teacher's information
http://orion.sci.muni.cz/kgmb/Student/7140.htm
The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 2010 - only for the accreditation, Autumn 2002, Autumn 2003, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2011 - acreditation, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, autumn 2017, Autumn 2018, Autumn 2019, Autumn 2020, autumn 2021, Autumn 2022, Autumn 2023, Autumn 2024.
  • Enrolment Statistics (Autumn 2004, recent)
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