PřF:C3060 Organic Chemistry-lab.course - Course Information
C3060 Organic Chemistry - laboratory course
Faculty of ScienceAutumn 2004
- Extent and Intensity
- 0/0/7. 7 credit(s). Recommended Type of Completion: graded credit. Other types of completion: z (credit).
- Teacher(s)
- RNDr. Slávka Janků, Ph.D. (seminar tutor)
- Guaranteed by
- RNDr. Slávka Janků, Ph.D.
Chemistry Section – Faculty of Science - Timetable
- Mon 7:00–13:50 MP1,01014, Tue 7:00–13:50 MP1,01014, Wed 7:00–13:50 MP1,01014, Thu 7:00–13:50 MP1,01014, Fri 7:00–13:50 MP1,01014
- Prerequisites
- C1080; You have to pass tests of your knowledge.
- Course Enrolment Limitations
- The course is also offered to the students of the fields other than those the course is directly associated with.
- fields of study / plans the course is directly associated with
- Analytical Chemistry (programme PřF, B-CH)
- Analytical Chemistry (programme PřF, M-CH)
- Analytical Chemistry (programme PřF, N-CH)
- Inorganic Chemistry (programme PřF, B-CH)
- Inorganic Chemistry (programme PřF, M-CH)
- Inorganic Chemistry (programme PřF, N-CH)
- Applied Biochemistry (programme PřF, B-CH)
- Biochemistry (programme PřF, B-CH)
- Biochemistry (programme PřF, M-CH)
- Biochemistry (programme PřF, N-CH)
- Physical Chemistry (programme PřF, B-CH)
- Physical Chemistry (programme PřF, M-CH)
- Physical Chemistry (programme PřF, N-CH)
- Chemistry (programme PřF, M-CH)
- Chemistry (programme PřF, B-CH)
- Environmental Chemistry (programme PřF, B-CH)
- Environmental Chemistry (programme PřF, M-CH)
- Environmental Chemistry (programme PřF, N-CH)
- Macromolecular Chemistry (programme PřF, B-CH)
- Macromolecular Chemistry (programme PřF, M-CH)
- Macromolecular Chemistry (programme PřF, N-CH)
- Organic Chemistry (programme PřF, B-CH)
- Organic Chemistry (programme PřF, M-CH)
- Organic Chemistry (programme PřF, N-CH)
- Upper Secondary School Teacher Training in Chemistry (programme PřF, M-CH)
- Course objectives
- Fundamental laboratory methods of organic chemistry for synthesis (heating, stirring, cooling, introduction of gases, working with decrease of pressure, drying) and separation of organic compounds (filtering, crzstallization, distillation, extraction). The methods are trained an the compounds synthesis of important types of organic reactions. The products are characterized bz melting point, thin-layer chromathography, refractive index, and infra-red spectroscopy.
- Syllabus
- 1. a) Ethyl bromide (SN2 mechanism, distillation) b) tert-Butyl chloride (SN1 mechanism, distillation) 2. 3-Phenylpropanoic acid (Catalytic hydrogenation, work with hydrogen, recrystallization, work with rotary evaporator) 3. Phenole nitration(SEAr mechanism , steam distillation , recrystallization) 4. Azobenzene (electrochemical reduction, recrystallization, TLC) 5. Ethyl 3-oxobutanoate ethylenacetale(AN mechanism to C=O, azeotropic and vacuum distillation, work with rotary evaporator) 6. a) 4,4-diphenyl-4-hydroxy-2-butanone ethylenacetale (AN mechanism to C=O, extraction, work with rotary evaporator, recrystallization) b) 4,4-Diphenyl-4-hydroxy-2-butanone (acid catalyzed hydrolysis of acetale, extraction, work with rotary evaporator, recrystallization) 7. 3-Nitroacetophenone (SEAr mechanism , recrystallization, IR spectroscopy) 8. a) 1-(3-Nitrophenyl)ethanol (selective reduction, extraction, recrystallization, IR spectroscopy) b) 3-Aminoacetophenone (selective reduction, recrystallization, IR spectroscopy) 9. Pinacol (metal reduction in anhydrous non-polar solvents, work with rotary evaporator) 10. Benzoic acid(AN to C=O, work with anhydrous solvents, extraction, sublimation) 11. Anthranilic acid (Hofmannovo odbourávání amide, recrystallization) 12. Ethyl-acetate (esterifikace, distillation) 13. 2-Hydroxy-5-methyl-2'-nitroazobenzene (diazotization and diazonium coupling, recrystallization, TLC) 14. 2-(2-Hydroxy-5-methylfenyl)benzotriazol (biochemical reductive cyclization, extraction, work with rotary evaporator, recrystallization) 15. 2-chlorbenzoic acide (diazotisation a Sandmayer reakction, recrystallization) Every student have to pass at least 14 practices. Practice 3, 5, 6, 7, 10 a 15 are required.
- Literature
- NOVÁČEK, Eduard and Milan POTÁČEK. Laboratorní technika ke cvičení z metod organické chemie. Edited by Slávka Janků. 1. vyd. Brno: Masarykova univerzita, 1997, 91 s. ISBN 8021015004. info
- Assessment methods (in Czech)
- Laboratorní cvičení ukončené klasifikovaným zápočtem.
- Language of instruction
- Czech
- Further comments (probably available only in Czech)
- The course can also be completed outside the examination period.
The course is taught annually.
General note: Vyučují učitelé katedry organické chemie.
- Enrolment Statistics (Autumn 2004, recent)
- Permalink: https://is.muni.cz/course/sci/autumn2004/C3060