Bi5180 Quantitative genetics

Faculty of Science
Autumn 2007 - for the purpose of the accreditation
Extent and Intensity
2/2/0. 4 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
Teacher(s)
RNDr. Ing. Karel Chroust, Ph.D. (lecturer)
Guaranteed by
RNDr. Ing. Karel Chroust, Ph.D.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Ing. Karel Chroust, Ph.D.
Prerequisites (in Czech)
( Ex_3162 Obecná genetika || Imp_9126 Obecná genetika || B1900 Basic genetics || BMB32 Basic genetics || B6730 Genetics || B8470 Genetics || B3060 Basic genetics || Bi3060 Basic genetics ) && ( Bi5040 Biostatistics - basic course || NOW( Bi5040 Biostatistics - basic course ))
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Genetic constitution of a population, small population. Continuous variability. Values and means, Variance. Breeding value. Resemblance between relatives. Heritability. Inbreeding. Selection. Threshold, Correlated, and Metric characters under population. Segregating analysis. Quantitative genetics in man, animals and plants. Molecular methods in quantitative genetics.
Syllabus
  • History of Quantitative Traits. Continuous variation, values and means, population means, average effect, metric characters, Pascal triangle. Components of variance, genetic and environmental variance, repeatability. Resemblance between relatives, genetic covariance. Inbreeding, pedigreed population. Estimation of heritability, human data, twins, assortative mating, precision of estimates and design of experiments. Selection between population, within population, measurement of response, index selection. Segregation analysis. Human quantitative traits. Quantitative traits in animals and plants.
Literature
  • Falconer, D. S. - Mackay, Trudy F. C. Introduction to quantitative genetics [Falconer, 1997]. 4th ed. Essex : Longman, 1997. xv, 464 s. r99. ISBN 0-582-24302-5.
Language of instruction
Czech
Further Comments
Study Materials
The course is taught annually.
The course is taught: every week.
The course is also listed under the following terms Spring 2011 - only for the accreditation, Autumn 2002, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Spring 2010, Spring 2011, Spring 2012, spring 2012 - acreditation, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.