Bi7575 Stem Cell Physiology

Faculty of Science
Autumn 2014
Extent and Intensity
2/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
Teacher(s)
Mgr. Jiří Pacherník, Ph.D. (lecturer)
Guaranteed by
Mgr. Jiří Pacherník, Ph.D.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: Mgr. Jiří Pacherník, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science
Timetable
Mon 9:00–10:50 B11/235
Prerequisites (in Czech)
Bi3030 Animal physiology && Bi4020 Molecular biology
Předmět je vhodný pro studenty třetích a vyších ročníků biologických a lékařských oborů.
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
At the end of the course the students are able to: Understand and explain developmental processes leading to stem cells population; Characterize basic features of stem cells; Explain the role of various cell signaling pathways in maintenance of stem cells; Interpret and explain recent knowledge and problems in stem cell biology and its applicability in medicine; Formulate and discuss hypothesis about role of stem cell in tissue regeneration.
Syllabus
  • 1. Stem cells, totipotency, pluripotency, multipotency; 2.Self-renewal, proliferation, differentiation, redifferentiation, selection and apoptosis; 3. Embryonic stem cells; 4. Germ cells; 5. Somatic stem cells; 6. Carcinoma stem cells; 7. Neural stem cells; 8. Hematopoietic stem cells; 9. Epidermis and colon stem cells; 10. Mesenchymal and bone marrow stem cells; 11. Stem cells and cell therapy; 12. Stem cells differentiation in vitro; 13. Application of stem cells in toxicology; 14. Therapeutic cloning; 15. Embryonic stem cells and genetically modified organism. Recommended literature Essentials of Stem Cell Biology, First Edition (Hardcover) by Robert Lanza, E. Donnall Thomas, James Thomson, Roger Pedersen, John Gearhart (Editor), Brigid Hogan (Editor), Douglas Melton (Editor), Michael West (Editor) ISBN: 0120884429 Handbook of Stem Cells, Two-Volume Set with CD-ROM, Volume 1-2, First Edition : Volume 1-Embryonic Stem Cells; Volume 2-Adult & Fetal Stem Cells (Hardcover) by Robert Lanza, Irving Weissman, James Thomson, Roger Pedersen, Brigid Hogan (Editor), John Gearhart (Editor), Helen Blau (Editor), Douglas Melton (Editor), Malcolm Moore (Editor), Catherine Verfaillie (Editor), E. Donnall Thomas (Editor), Michael West (Editor) ISBN: 0124366430 Stem Cells Handbook (Hardcover) by Stewart Sell (Editor) ISBN: 1588291138
Literature
  • Essentials of stem cell biology. Edited by R. P. Lanza. Amsterdam: Elsevier Academic Press, 2006, xxxi, 548. ISBN 0120884429. info
  • Stem cells handbook. Edited by Stewart Sell. Totowa, N.J.: Humana Press, 2004, xiii, 509. ISBN 1588291138. info
Teaching methods
lectures
Assessment methods
The course is finished by the oral exam. Students must explain the chosen topic from past lectures and be able to explain its connection with other subjects. Evaluation by the teacher
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
The course is taught once in two years.
Information on the per-term frequency of the course: Vypisován pouze v sudých letech.
Information on course enrolment limitations: Na předmět se vztahuje povinnost registrace, bez registrace může být znemožněn zápis předmětu!
The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 2010 - only for the accreditation, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2011 - acreditation, Autumn 2012, Autumn 2013, Autumn 2016, Autumn 2018, Autumn 2020, Autumn 2022, Autumn 2023, Autumn 2024.
  • Enrolment Statistics (Autumn 2014, recent)
  • Permalink: https://is.muni.cz/course/sci/autumn2014/Bi7575