C9090 Secondary Metabolites

Faculty of Science
Autumn 2014
Extent and Intensity
2/0/0. 2 credit(s) (fasci plus compl plus > 4). Recommended Type of Completion: zk (examination). Other types of completion: k (colloquium).
Teacher(s)
RNDr. Ivo Pluháček (lecturer)
Guaranteed by
RNDr. Ivo Pluháček
Department of Biochemistry – Chemistry Section – Faculty of Science
Supplier department: Department of Biochemistry – Chemistry Section – Faculty of Science
Timetable
Wed 13:00–14:50 B11/235
Prerequisites
Basic overview of biochemistry and organic chemistry.
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
there are 11 fields of study the course is directly associated with, display
Course objectives
Upon successful completion of the course lectures secondary metabolites student; defines the basic relationships between primary and secondary metabolism; is able to explain the synthesis of the major groups of secondary metabolites; demonstrate their effects on living organisms, in relation to the structure of these substances; analyze the possibility of further discoveries of new natural products and their use; summarize lessons learned about secondary metabolites and their use in human medicine; evaluate the use of the acquired knowledge for future orientation in a large area of natural substances.
Syllabus
  • Secondary metabolism, methods of study
  • non-protein aminoacids
  • biologically active peptides
  • toxins
  • antibiotics
  • amines
  • alkaloids
  • glycosides
  • shikimic acid pathway and polyketides
  • terpenoids
  • odorous substances
  • carcinogens
  • hallucinogens
  • insect chemical communication.
Literature
    recommended literature
  • MACHOLÁN, Lumír. Sekundární metabolity. 2., dopl. vyd. Brno: Masarykova univerzita, 2003, 150 s. ISBN 8021030682. info
    not specified
  • HRDINA, Vratislav. Přírodní toxiny a jedy. 1. vyd. Praha: Galén, 2004, xvi, 302. ISBN 8024608235. info
  • KOREŇOVÁ, Anna and Michal UHER. Bioorganická chémia v otázkách a odpovediach. 1. vyd. Bratislava: Slovenská technická univerzita, 2002, 306 s. ISBN 8024603829. info
  • MACHOLÁN, Lumír. Sekundární metabolity. 1. vyd. Brno: Masarykova univerzita, 1998, 147 s. ISBN 80-210-1735-X. info
  • TORSSELL, Kurt B. G. Natural product chemistry :a mechanistic, biosynthetic and ecological approach. Stockholm: Apotekarsocieteten, 1997, 480 s. ISBN 91-86274-63-5. info
  • ČERVINKA, Otakar. Chemie organických sloučenin. Vyd. 1. Praha: Státní nakladatelství technické literatury, 1987, 1052 s. info
Teaching methods
Lectures with experiments.
Assessment methods
The student is examined from one area of secondary metabolites, which selects.During examination is continuously asked about fundamental representatives from other parts of the subject. The overview and the identification of chemical formula of the main representatives is classify by mark A-F. During the colloquium is a group of students reiterated the entire subject matter, during which students are actively involved in discussions and, together with checking attendance at lectures are judged by the letters p or n
Language of instruction
Czech
Further comments (probably available only in Czech)
The course can also be completed outside the examination period.
The course is taught annually.
The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 1999, Autumn 2010 - only for the accreditation, Autumn 2000, Autumn 2001, Autumn 2002, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2011 - acreditation, Autumn 2012, Autumn 2013, Autumn 2015.
  • Enrolment Statistics (Autumn 2014, recent)
  • Permalink: https://is.muni.cz/course/sci/autumn2014/C9090