PřF:Bi7420 Genome analysis methods - Course Information

Bi7420 Modern methods for genome analysis

Extent and Intensity

1/0. 1 credit(s) (plus extra credits for completion). Type of Completion: k (colloquium).

Teacher(s)

MVDr. Boris Tichý, Ph.D. (lecturer)
RNDr. Jitka Malčíková, Ph.D. (lecturer)
prof. MUDr. Mgr. Marek Mráz, Ph.D. (lecturer)
Mgr. Nikola Tom, Ph.D. (lecturer)
Mgr. Karol Pál, Ph.D. (lecturer)
doc. Mgr. Martin Trbušek, Dr. (lecturer)

Guaranteed by

prof. RNDr. Jan Šmarda, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Jitka Malčíková, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science

Timetable

Mon 19. 9. to Sun 18. 12. Fri 10:00–11:50 B11/235

Prerequisites (in Czech)

Bi1700 Cell Biology && ( Bi4010 Essential molecular biology || Bi4020 Molecular biology ) && ( Bi4020c Essential methods in mol. biol || Bi6400 Methods of molecular biology )

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.
The capacity limit for the course is 40 student(s).
Current registration and enrolment status: enrolled: 0/40, only registered: 0/40, only registered with preference (fields directly associated with the programme): 0/40

fields of study / plans the course is directly associated with

• Medical Genetics and Molecular Diagnostics (programme PřF, N-BI)
• Molecular Biology and Genetics (programme PřF, N-EXB)
• Special Biology (programme PřF, N-EXB)
• Special Biology (programme PřF, N-EXB, specialization Experimentální biologie živočichů a imunologie)
• Special Biology (programme PřF, N-EXB, specialization Mikrobiologie a molekulární biotechnologie)

Course objectives

At the end of the course students should get familiar with the modern molecular-biology techniques and explain the principles of microarray and next generation sequencing technologies

Syllabus

• 1. Microarrays - technological aspects: expression, CGH, SNP arrays, resequencing and protein arrays; 2. Next generation sequencing (NGS) – technological aspects of different NGS platforms 3. Library preparation for NGS 4. Methods for non-coding RNA analysis – miRNA, lncRNA, examples of applications in oncology 5. Data analysis – bioinformatics and statistics 6. Aplications and experiment design

Literature

• Koubková L, Vojtěšek B, Vyzula R. Next generation sequencing -  application in clinical practice. Klin Onkol. 2014;27 Suppl 1:S61-8.

Teaching methods

Lectures.

Assessment methods

written test

Language of instruction

Czech

Further Comments

Study Materials
The course is taught annually.

• Enrolment Statistics (Autumn 2016, recent)
  
• Permalink: https://is.muni.cz/course/sci/autumn2016/Bi7420