C5150 Trends in Analytical Chemistry

Faculty of Science
Autumn 2019
Extent and Intensity
2/0/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
Teacher(s)
prof. Mgr. Jan Preisler, Ph.D. (lecturer)
Guaranteed by
prof. Mgr. Jan Preisler, Ph.D.
Department of Chemistry – Chemistry Section – Faculty of Science
Supplier department: Department of Chemistry – Chemistry Section – Faculty of Science
Timetable
Mon 9:00–10:50 C14/207
Prerequisites
Passing courses Analytical chemistry I (C3100) and Analytical chemistry II (C4050).
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
there are 9 fields of study the course is directly associated with, display
Course objectives
During the course consisting of lectures given by experts of the Institute of Analytical Chemistry of Academy of Sciences of the Czech Republic students will learn advanced analytical techniques. The course also involves a visit of the Institute of Analytical Chemistry of ASCR.
Learning outcomes
The course will widen students' knowledge of modern analytical chemistry. Students will visit a top scientific institution in the country.
Syllabus
  • Outline of the Trends in Analytical Chemistry course
  • 21. 9. 2017 doc. RNDr. Michal Roth, CSc. Compressed fluids in analytical separations. Supercritical fluids and compressed liquids – similarities and differences, applications in chromatography and sample preparation, supercritical fluid chromatography, supercritical fluid extraction, pressurized hot water extraction. Ionic liquids – motivation, properties, applications. Supercritical water as an agent to treat fused silica capillaries.
  • 5. 10. 2017 Mgr. Markéta Vaculovičová, Ph.D. Nanoparticles in bioanalytical applications. List of nanoparticles used for in vitro and in vivo detection applications and imaging. Highlight of basic properties of various nanoparticle types, which are employed in bioanalysis and diagnostics.
  • 12. 10. 2017 doc. RNDr. Karel Šlais, DrSc. Preparative and analytical isoelectric focusing. Principles and variants of instrumental arrangement (capillary, gel, preparative channel), detection, staining, standards and pI-markers, applications in analysis of proteins and microorganisms, continuous methods, coupling to liquid chromatography and mass spectrometry. Current results – new electrolyte systems and focusing devices.
  • 19. 10. 2017 RNDr. Pavel Kubáň, Ph.D. DSc. Application of membrane-based pre-separation techniques in analysis of environmental, biological and clinical samples. New trends in treatment and pre-concentration of complex samples, examples of off-line and on-line couplings with current analytical instruments, examples of practical solutions of real-world problems.
  • 26. 10. 2017 Ing. František Foret, CSc. Principles of microfabrications for analytical instrumentation. Coupling of microseparation techniques to mass spectrometry.
  • 2. 11. 2017 doc. RNDr. Bohumil Dočekal, CSc. New approaches in atomic spectroscopy. Laboratories for trace analysis – “clean environment”.
  • 9. 11. 2017 Ing. Karel Klepárník, CSc. Current instruments for genetic research, medical diagnostics and molecular identification of organisms (principles of capillary electrophoresis and mass spectrometry for DNA analysis, separation media, laser-induced fluorescence, mutations and polydispersity of DNA, sample preparation for DNA analysis (cloning, restriction fission, DNA amplification by polymerase chain reaction, Sanger sequenation reaction), DNA sequenation, analysis of polymorphism of restriction fragments, ssDNA conformation polymorphism analysis, denaturation analysis, applications of capillary electrophoresis and mass spectrometry for medical diagnostics and molecular identification of organisms. Nanotechnology for genomic DNA sequenation.
  • 16. 11. 2017 doc. RNDr. Petr Kubáň, Ph.D. Analytical chemistry in point-of-care (POC) diagnostics. Definition of concepts, history, types of POC devices, examples. Indicator papers, lateral flow assays, paper-based microfluidics, portable analysers. Types of reactions, principles, detection. Example applications from our laboratory. New trends.
  • 23. 11. 2017 Mgr. Jana Křenková, Ph.D., Ing. Dana Moravcová, Ph.D. Monoliths in separation techniques. A short overview of monoliths employed in separation techniques with emphasis on synthesis, characterization and applications of monoliths in analysis of biological samples.
  • 30. 11. 2017 RNDr. Pavel Mikuška, CSc. Atmospheric aerosols. Basic definitions and terms, effects of aerosols on environment and human health, physical properties, aerosol sources, size distribution and concentration measurements, chemical composition, specific types of aerosols (bioaerosols, nanoaerosols, indoor aerosols), aerosol concentrations in the Czech Republic.
  • The course will terminate on December 7, 2017 with an excursion to the labs of The Institute of Analytical Chemistry of the Czech Academy of Sciences.
Literature
  • Supplementary materials will be provided by the external lecturers
Teaching methods
Lectures and a visit of external workplace. The lectures are given in English.
Assessment methods
Final written examination
Language of instruction
English
Further Comments
Study Materials
The course is also listed under the following terms Autumn 2010 - only for the accreditation, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2011 - acreditation, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, autumn 2017, Autumn 2018, autumn 2021, Autumn 2023.
  • Enrolment Statistics (Autumn 2019, recent)
  • Permalink: https://is.muni.cz/course/sci/autumn2019/C5150