PřF:E3230 Human Pathophysiology - Course Information

E3230 Human Pathophysiology

Extent and Intensity

2/0/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).

Teacher(s)

prof. MUDr. Julie Dobrovolná, Ph.D. (lecturer), Mgr. Jan Kučera, Ph.D. (deputy)
Mgr. Simona Holotová (seminar tutor), Mgr. Jan Kučera, Ph.D. (deputy)

Guaranteed by

prof. MUDr. Julie Dobrovolná, Ph.D.
RECETOX – Faculty of Science
Contact Person: prof. MUDr. Julie Dobrovolná, Ph.D.
Supplier department: RECETOX – Faculty of Science

Timetable

Fri 8:00–9:50 D29/252-RCX1

Prerequisites

BKFY0121c+p a BKFY0122c+p

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

• Environment and Health (programme PřF, N-ZPZ)

Course objectives

The aim of the course is to provide a structured overview of the basic processes and concepts of human pathophysiology and related health outcomes, especially in the diseases with strong environmental influences.

Learning outcomes

After the completion of the course, the student will be able to: 1. Describe the general physiological processes used by the body to maintain homeostasis 2. Describe the basic ethiopathogenesis of diseases, including the bodily response to adverse environmental factors 3. Explain the ethiopathogenesis of selected diseases and give the basic definition of the disease 4. Discuss the most important civilization diseases including their mechanisms and possible therapeutic actions.

Syllabus

• 1. Basic categories of diseases and terminology (characteristics and classification of diseases) 2. Inflammation (definition, mediators, acute and chronic inflammation, disease examples) 3. Basic immunology (basic pathways, mediators, hypersensitivity, autoimmunity, immunodeficiencies) 4. Congenital, genetic and chromosomal disorders (causes, definition of damage in utero, multifactorial inheritance, diagnosis) 5. Disease transmission (epidemiology, disease control, pathogenicity factors, antibiotic therapy, viral, bacterial, fungal and parasitic diseases) 6. Carcinogenesis (etiology, diagnosis, a very short introduction to the histopathological classification of tumors) 7. Pathogenesis of disorders of the heart and circulatory system A (vascular disorders, heart disorders, coagulation disorders) 8. Pathogenesis of disorders of the heart and circulatory system B (congestive heart failure, ischemic heart disease, stroke, disorders of the venous system, disorders of the lymphatic system) 9. Disorders of the gastrointestinal tract (liver disorders, stomach diseases, intestinal diseases, idiopathic intestinal inflammations) 10. Pathogenesis of reproductive disorders (female and male disorders, disorders associated with pregnancy and childbirth) 11. Pathogenesis of lung diseases (infectious disorders, obstructive vs. restrictive disorders, asthma, COPD, lung cancer)

Literature

required literature
• NEČAS, Emanuel. Obecná patologická fyziologie. 2. vyd. Praha: Karolinum, 2006, 377 s. ISBN 9788024612911. info
• FÖLSCH, Ulrich R., Kurt KOCHSIEK and Robert F. SCHMIDT. Patologická fyziologie. Translated by Richard Rokyta - Jiří Mareš. Vyd. 1. české. Praha: Grada, 2003, 586 s. ISBN 802470319X. info

Teaching methods

Education is performed as lectures with Powerpoint presentation. Understanding of mechanisms and consequences is emphasized. Students are frequently asked questions to think about actual topic. They are encouraged to ask questions and be in interaction with the lecturer.

Assessment methods

Attending lectures is not mandatory, but strongly recommended for understanding the topics discussed. The final assessment (at the end of the semester) will be conducted in the form of an oral exam.

Language of instruction

Czech

Further Comments

Study Materials
The course is taught annually.

• Enrolment Statistics (Autumn 2023, recent)
  
• Permalink: https://is.muni.cz/course/sci/autumn2023/E3230