Bi5614en Genetics in animal model organisms

Faculty of Science
Autumn 2024
Extent and Intensity
1/0/0. 1 credit(s) (plus extra credits for completion). Type of Completion: k (colloquium).
In-person direct teaching
Teacher(s)
Liam Keegan, PhD. (lecturer)
Guaranteed by
Liam Keegan, PhD.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: Liam Keegan, PhD.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science
Timetable
Fri 13:00–13:50 B11/333
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Learn genetics with model organisms
Learning outcomes
Learn genetics with model organisms
Syllabus
  • 1. History: After Mendel rediscovery; beginnings of Drosophila and rodent genetics. Life cycles, breeding and genetic methods for Drosophila and mice. 2. Drosophila Balancer chromosomes; Bar eye, Curly wings and Stubble bristle dominant balancer markers and other markers. Genetic screens in flies, mice and zebrafish 3. Drosophila embryonic development and metamorphosis; The Wieschaus, Nusslein-Vollhard genetic screen for larval segmentation and patterning mutants 4. Other important genetic screens for Drosophila developmental mutants; screens in Daniel St Johnston review. 5. Selected topics in fly and mouse genetics; Homeotic genes, planar cell polarity and organ specification in flies, mice and zebrafish 6. Growth control, cancer and cell death in flies, mice and fish 7. Innate immunity in flies, mice and fish. Ageing. 8. Genetic control of nervous system development in Drosophila, specification of neuronal cell types, motorneuron specification and coordination in flies, mice and fish 9. Genetic control of development in sensory systems, vision, olfaction in flies, mice and fish 10. Genetic investigations of learning, memory, forgetting in flies, mice and fish 11. Genetic investigations of specific behaviours; circadian rhythms, sleep, mating etc. in flies, mice and fish 12. Other model systems, with invited lecturers; C. elegans, Killifish, other rodents maybe 13. Other model systems, with invited lecturers; C. elegans maybe, Killifish, other rodents 14. Other model systems, with invited lecturers; C. elegans maybe, Killifish, other rodents
Teaching methods
Lectures with some assigned reading
Assessment methods
Continuous assessment/student engagement
Language of instruction
English
Further Comments
Study Materials
The course is taught annually.
  • Enrolment Statistics (recent)
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