Bi6170 Genetics II

Faculty of Science
Autumn 2024
Extent and Intensity
2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
In-person direct teaching
Teacher(s)
prof. RNDr. Jana Řepková, CSc. (lecturer)
doc. RNDr. Petr Kuglík, CSc. (lecturer)
RNDr. Vladimíra Vallová, Ph.D. (lecturer)
Guaranteed by
prof. RNDr. Jana Řepková, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Jana Řepková, CSc.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science
Timetable
Thu 10:00–11:50 B11/305
Prerequisites
Bi3060 Basic genetics
Bi3060 course
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
there are 11 fields of study the course is directly associated with, display
Course objectives
The aim of the course is to explain the genetic principles: non-mendelian inheritance of extranuclear DNA of different organisms, molecular organization of mitochondrial and chloroplast DNA, human behavioral genetics and other model animals, mutagenesis, genetic variability of mutagenic responses, special cases of linkage mapping such as analysis of tetrades, mitochondrial disorders and chloroplast engineering.
Learning outcomes
At the end of the course the students will be able to understand the special topics such as principles of non-mendelian inheritance of extranuclear DNA of different organisms; molecular organization of mitochondrial and chloroplast DNA; genetic principles of human behavioral genetics and other model animals; genetic principles of mutagenesis; genetic variability of mutagenic responses; students will be able to explain special cases of linkage mapping such as analysis of tetrades, to describe causes of human mitochondrial disorders and results of chloroplast engineering.
Syllabus
  • 1. Extranuclear inheritance - chloroplast DNA , mitochondrial DNA and their description. 2. Comparison and inheritance principles in different eukaryotic organisms. Mitochondrial genome, mitochondrial inheritance and rare human diseases. 3. Plastidial genome and plastidial inheritance. Chloroplast engineering. Infectious particles. 4. Special cases of linkage mapping. 5. Mutations and their importance in genetics. Terms, meaning, history of study. Classification of mutations. Genetic consequences of genic and chromosomal mutations. Examples of hereditary human diseases. 6. Principles of radiobiology. UV and ionising radiations - mutagenic effects. 7. Chemical mutagenesis. Molecular mechanisms, promutagens. Genotoxic substances in environment. 8. Genetic variability of mutagenic responses. 9. Behavioral genetics - methodology. 10. Behavioral genetics and man.
Literature
    recommended literature
  • SNUSTAD, D. Peter and Michael J. SIMMONS. Genetika. Translated by Jiřina Relichová. 1. vyd. Brno: Masarykova univerzita, 2009, 871 pp. ISBN 978-80-210-4852-2. Online knihkupectví Munipress info
  • HATINA, Jiří and Brian D. SYKES. Lékařská genetika : problémy a přístupy. Vyd. 1. Praha: Academia, 1999, 296 s. ISBN 8020007008. info
  • RELICHOVÁ, Jiřina and Jaroslav MALINA. Panoráma biologické a sociokulturní antropologie 2: Genetika (Panorama of biological and sociocultural anthropology 2: Genetics). Editor: Jaroslav Malina. Brno (CZ): Nadace Universitas Masarykiana v Brně, nakladatelství a vydavatelství Nauma v Brně, 2000, 89 pp. Modulové učební texty pro studenty antropologie. ISBN 80-210-2473-9. info
Teaching methods
Lectures weekly. Powerpoint presentations are available to students.
Assessment methods
Written exam consisting of 20 questions evaluated by 20 points. Combination of open questions with brief answers and multiple choice questions. At least 60% success rate is needed to pass exam.
Language of instruction
Czech
Further Comments
The course is taught annually.
The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Autumn 2010 - only for the accreditation, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2011 - acreditation, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, autumn 2017, Autumn 2018, Autumn 2019, Autumn 2020, autumn 2021, Autumn 2022, Autumn 2023.
  • Enrolment Statistics (recent)
  • Permalink: https://is.muni.cz/course/sci/autumn2024/Bi6170