PřF:B6130 Molecular biology - Course Information

B6130 Molecular biology

Faculty of Science
Spring 2000

Extent and Intensity

4/3/0. 4 credit(s). Type of Completion: zk (examination).

Teacher(s)

Guaranteed by

Prerequisites (in Czech)

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

Syllabus

Proteins (primary, secondary and higher structures of proteins and their biological functions). Nucleic acids (primary, secondary and tertiary structure of DNA and RNA, different conformations of DNA and their significance in biological systems). Interactions of proteins with DNA. Genetic information and the genetic code. Molecular structure of procaryotic and eucaryotic genome. Replication of procaryotic and eucaryotic genome. Transcription of procaryotic and eucaryotic genome. Postranscriptional modification and processing of RNA, especially in eucaryotes. Mechanisms of splicing and selfsplicing. Translation of procaryotic and eucaryotic mRNA. Posttranslational processing. Regulation of gene expression in procaryotes and eucaryotes. Signal pathways in mammal cells and their relation to the activation of transcription factors. Molecular basis of acquired immunity. Molecular basis of cancerogenesis (oncogenes, antioncogenes). Mechanisms of replication of viral DNA and RNA, transcription of viral DNA and translation of viral RNA. Molecular mechanisms of mutagenesis and recombination. Transposons. Repair mechanisms of damaged DNA. Elements of molecular evolution. Origin of life from the aspects of molecular biology. On the whole, the general molecular processes occuring in living systems are emphasized in this lecture with respect to the specificities characteristic of the main groups of living systems (bacteria, archea, plants, animals and viruses).

Language of instruction

Czech

Further Comments

The course can also be completed outside the examination period.
The course is taught annually.
The course is taught: every week.

Listed among pre-requisites of other courses

Bi6400 Methods of molecular biology
souhlas || Ex_3065 || Imp_9115 || B3120 || B4030 || B5740 || B6130 || B7940 || B4020 || Bi4010 || Bi4020
Bi6400c Methods of Molecular Biology - practice
(Ex_3065 || Imp_9115 || B3120 || B4030 || B5740 || B6130 || B7940 || B4020 || Bi4020 || Bi4035) && NOW(Bi6400) && !B6405
Bi7250 Medical genetics and genetic counseling
(Ex_3162 || Imp_9126 || B1900 || BMB32 || B6730 || B8470 || B3060 || Bi3060) && (Ex_3065 || Imp_9115 || B3120 || B4030 || B5740 || B6130 || B7940 || B4020 || Bi4020) && (Ex_2315 || BMB41 || B6270 || Bi6270 || NOW(Bi6270)) && !B7250
Bi8240 Plant genetics
(Ex_3162 || Imp_9126 || B1900 || BMB32 || B6730 || B3060 || Bi3060) && (Ex_3065 || Imp_9115 || B3120 || B4030 || B5740 || B6130 || B7940 || B4020 || Bi4020 || NOW(Bi4020))
Bi8280 Animal genetics
(Ex_3162 || Imp_9126 || B1900 || BMB32 || B6730 || B3060 || Bi3060) && (Ex_3065 || Imp_9115 || B3120 || B4030 || B5740 || B6130 || B7940 || B4020 || Bi4020)