PřF:C8635 Genetic Ecotoxicology

C8635 Genetic Ecotoxicology

Faculty of Science
Spring 2000

Extent and Intensity

2/0/0. 4 credit(s). Type of Completion: zk (examination).

Teacher(s)

RNDr. Ing. Karel Chroust, Ph.D. (lecturer)

Guaranteed by

Prerequisites (in Czech)

B3060 Basic genetics && ( B4020 Molecular biology || B6130 Molecular biology || B5740 Molecular biology )

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

Syllabus

Genetic ecotoxicology as a science. Ecotoxicology and genetic toxicology. Genetic toxicology, mutagenesis in organisms and populations. Spontaneous and induced mutations. Gene mutations, chromosomal abberations, aneuploidy and polyploidy. Risk factors identification, models, acute and chronical exposition. Gametic and somatic mutations. DNA repairs, recombinations. In vivo and in vitro assays, procaryotic and eucaryotic organisms. Gametic and somatic assays, metabolic activation, transgenic systems. Choice of laboratory and in situ genotoxicity tests. Batery of tests, predictive value. Molecular analysis of mutations. Monitoring of human population, epidemiological and clinical study. Legislative and recommendations in the Czech Republic and EC.

Language of instruction

Czech

Further Comments

The course is taught annually.
The course is taught: every week.

The course is also listed under the following terms Spring 2001, Spring 2002.