Bi8970 Early Molecular Evolution

Faculty of Science
Spring 2008
Extent and Intensity
2/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: k (colloquium).
Teacher(s)
Edward N. Trifonov (lecturer), prof. RNDr. Jiří Fajkus, CSc. (deputy)
Guaranteed by
prof. RNDr. Jiří Fajkus, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Jiří Fajkus, CSc.
Prerequisites
Basic knowledge of molecular biology
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
The capacity limit for the course is 30 student(s).
Current registration and enrolment status: enrolled: 0/30, only registered: 0/30, only registered with preference (fields directly associated with the programme): 0/30
fields of study / plans the course is directly associated with
Course objectives
In addition to protein-coding message the nucleotide sequences carry instructions for DNA folding, transcription, translation framing, gene splicing, fast adaptation code, and many more (1, 2). Every sequence element belongs simultaneously to several different messages superimposed on one another. The codes of protein sequences are of this nature as well. Most prominent examples of the code overlapping and interaction will be considered. The course is based largely on the most recent publications. This includes the latest developments on the chromatin code and its interactions with other codes (3, 4). Ref. (2) is an extended summary of the course. References: 1. Trifonov, E. N., Sequence codes. In: "Encyclopedia of Molecular Biology", T. E. Creighton, Ed., John Wiley & Sons, Inc., New York, 1999, p. 2324-2326. 2. Trifonov, E. N., Codes of biosequences. In: The Codes of Life. The Rules of Macroevolution. Barbieri, M. (ed.). Springer. New York, in press. 3. Trifonov, E. N., Kogan, S., Cohanim, A. B. Latest on the nucleosome positioning sequence patterns. In "DNA Structure, Chromatin and Gene Expression" (Eds. R. Kiyama, M. Shimizu), Transworld Research Network, Trivandrum (India), pp 43-54 (2006). 4. F. Salih, B. Salih, E. N. Trifonov, Sequence-directed mapping of nucleosome positions, JBSD in press.
Assessment methods (in Czech)
Lectures will be given in English within a period of 14 working days (2-4 lessons per day) within a period since 2 to 25 April, 2008. The course will be concluded by colloquium after the last lesson.
Language of instruction
English
Follow-Up Courses
Further comments (probably available only in Czech)
The course is taught annually.
The course is taught: in blocks.
The course is also listed under the following terms Spring 2011 - only for the accreditation, Spring 2009, Spring 2010, Spring 2011, spring 2012 - acreditation.
  • Enrolment Statistics (Spring 2008, recent)
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