Bi6888 Modelování a konstrukce proteinů

Přírodovědecká fakulta
jaro 2010
Rozsah
0/2. 2 kr. (příf plus uk plus > 4). Ukončení: z.
Vyučující
prof. Mgr. Jiří Damborský, Dr. (cvičící)
Mgr. Andrea Fořtová, Ph.D. (cvičící)
doc. Mgr. Radka Chaloupková, Ph.D. (cvičící)
Mgr. Martina Pavlová, Ph.D. (cvičící)
prof. RNDr. Zbyněk Prokop, Ph.D. (cvičící)
Garance
prof. Mgr. Jiří Damborský, Dr.
Ústav experimentální biologie – Biologická sekce – Přírodovědecká fakulta
Kontaktní osoba: prof. Mgr. Jiří Damborský, Dr.
Rozvrh
Po 8:00–9:50 C04/211
Předpoklady
Completion of basic courses of biochemistry and/or molecular biology is a prerequisite for subscription to the course. ability to communicate in English
Omezení zápisu do předmětu
Předmět je nabízen i studentům mimo mateřské obory.
Předmět si smí zapsat nejvýše 20 stud.
Momentální stav registrace a zápisu: zapsáno: 0/20, pouze zareg.: 0/20, pouze zareg. s předností (mateřské obory): 0/20
Jiné omezení: Registration to this course must be approved by teachers. !The prerequisite of the possibility to sign in the course is participation on the scientific work in Loschmidt Laboratories.
Mateřské obory/plány
Cíle předmětu
The students will learn various aspects of research and development focused on construction of proteins by rational design and directed evolution in this seminar. Theoretical and experimental problems of protein engineering are being discussed, including transfer of the results from research to practice. The students refer once a week about the results of their own research projects as well as the results published in scientific literature within so called "Journal Clubs". They are supervised to critically access content and formal aspects of presentations. The students are being informed about hot news in the field presented at scientific conferences and refer about the meetings they have attended during the year. The students get first experience with chairing scientific discussions and learn how to prepare minutes from the meeting.
Osnova
  • Screening of New Proteins by Bioinformatic Analysis
  • Rational Design of Proteins by Computer Modelling
  • Construction of Modified Proteins by Site-Directed Mutagenesis and Directed Evolution
  • Characterization of Modified Proteins by Biochemical and Biophysical Techniques
Literatura
  • Protein Structure and Function, Gregory A. Petsko, Dagmar Ringe, New Science Press, 2004 ISBN 1405119225, 9781405119221, str. 195
Metody hodnocení
zápočet
Informace učitele
The course is also offered to the students of the fields other than those the course is directly associated with. Capacity limit for the course is 25 student(s). The course can also be completed outside the examination period. The course is taught annually. Information on course enrollment limitations: registration to this course must be approved by teachers
Další komentáře
Předmět je dovoleno ukončit i mimo zkouškové období.
Předmět je vyučován každý semestr.
Předmět je zařazen také v obdobích jaro 2011 - akreditace, podzim 2010 - akreditace, podzim 2008, jaro 2009, podzim 2009, podzim 2010, jaro 2011, podzim 2011, podzim 2011 - akreditace, jaro 2012 - akreditace, jaro 2013, jaro 2014, podzim 2014.