PřF:IC060 Organofluorine compounds - Course Information
IC060 Organofluorine compounds and strategy of their synthesis
Faculty of ScienceSpring 2011
- Extent and Intensity
- 2/0/0. 2 credit(s) (plus extra credits for completion). Recommended Type of Completion: z (credit). Other types of completion: zk (examination).
- Teacher(s)
- Prof. Jean-Philippe Bouillon (lecturer), prof. RNDr. Milan Potáček, CSc. (deputy)
- Guaranteed by
- prof. RNDr. Milan Potáček, CSc.
Department of Chemistry – Chemistry Section – Faculty of Science - Prerequisites
- Basic knowledge of organic chemistry
- Course Enrolment Limitations
- The course is offered to students of any study field.
- Course objectives
- Orientation in methods leading to fluorine derivatives of organic molecules and their reactivity
- Syllabus
- Organofluorine compounds and strategy of their synthesis : The lecture deals with the interests and applications of organofluorine compounds in our life. After a general introduction concerning the main properties of C-F bond and trifluoromethyl group (steric, energetic and electronic characteristics), the influence of introduction of a fluorine atom or CF3 group will be discussed, especially for the reactivity of fluorinated carbonyl derivatives. Then, the main aspect will be devoted to the two general strategies (trifluoromethylation or building blocks) for the synthesis of fluorinated aliphatic and aromatic compounds. Finally, few interesting biologically active compounds containing fluorine atom or CF3 group will be presented (anti-osteoporosis and anti-cancer properties).
- Teaching methods
- Lecture with practical demonstrations
- Language of instruction
- English
- Further comments (probably available only in Czech)
- The course is taught only once.
The course is taught: in blocks.
Note related to how often the course is taught: středa 27.4.2011 v 8.00 A8 / 309.
- Enrolment Statistics (recent)
- Permalink: https://is.muni.cz/course/sci/spring2011/IC060