PřF:C2200 Chemical synthesis - lab. - Course Information

C2200 Chemical synthesis - laboratory

Extent and Intensity

0/0/8. 8 credit(s). Type of Completion: graded credit.

Teacher(s)

RNDr. Slávka Janků, Ph.D. (seminar tutor)
Mgr. Jaromír Literák, Ph.D. (seminar tutor)
Ing. Alena Pálková (seminar tutor)
Mgr. Marie Petlachová, Ph.D. (seminar tutor)
Světlana Filípková (assistant)
Mgr. Zdeněk Moravec, Ph.D. (assistant)

Guaranteed by

prof. RNDr. Jiří Pinkas, Ph.D.
Department of Chemistry – Chemistry Section – Faculty of Science
Supplier department: Department of Chemistry – Chemistry Section – Faculty of Science

Timetable of Seminar Groups

C2200/01: Tue 8:00–15:50 C10/109, S. Janků, M. Petlachová
C2200/02: Wed 9:00–16:50 C10/109, J. Literák, A. Pálková

Prerequisites

( C1100 Introductory Chemistry Lab && C1020 General Chemistry && C1040 General Chemistry-sem. )||(PROGRAM(B-AB)&& C1020 General Chemistry && C4221 Laboratory techniques in biochemistry && C4222 Basic laboratory calculations )
Basic knowledge of general, inorganic and organic chemistry. Writing chemical equations, stoichiometric calculations, and calculations of solution concentration and mixing will be used extensively.

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.
The capacity limit for the course is 120 student(s).
Current registration and enrolment status: enrolled: 0/120, only registered: 0/120, only registered with preference (fields directly associated with the programme): 0/120

fields of study / plans the course is directly associated with

there are 13 fields of study the course is directly associated with, display

Course objectives

Basic laboratory course in preparative chemistry. Covers syntheses, properties and structures of simple inorganic and organic compounds, such as oxides, halides and other salts, acids and their functional derivatives, and complexes. At the end of the course students should be able to explain the principles that underpin selected synthetic processes, and why specialist techniques are required for their preparation.

Syllabus

• 1. Introduction, safety rules, laboratory notebook, worked example of experiment calculations. Requirements for passing the course. Preparation of orthoboric acid and potasium hydrosulfate.
  2. Preparation of bromoethane. Preparation of bezophenone oxime.
  3. Preparation of ethylmagnesium bromide and its diastereoselective addition to benzoin.
  4. Preparation of 3-nitroacetophenone.
  5. Preparation of 3-aminoacetophenone and 1-(3-nitrophenyl)ethanol.
  6. Preparation of ethyl 3-oxobutanoate ethylenacetal.
  7. Preparation of azo dyes, column chromatography.
  8. Preparation of metal acetylacetonate complexes. Thin-layer chromatography.
  9. Preparation of potassium chlorate. Preparation of hexaaquacobalt(II) chloride.
  10. Preparation of cobalt(III) coordination compounds.
  11. Preparation of boric oxide and trimethyl borate.
  12. Preparation of bismuth(III) oxide and bismuth.
  13. Synthesis of ferrocene.

Literature

• Masarykova univerzita. Přírodovědecká fakulta. Návody ke cvičení z anorganické chemie. Brno, Masarykova univerzita, 2006, 80 s.
• NOVÁČEK, Eduard and Milan POTÁČEK. Laboratorní technika ke cvičení z metod organické chemie. Edited by Slávka Janků. 1. vyd. Brno: Masarykova univerzita, 1997, 91 s. ISBN 8021015004. info
• KLIKORKA, Jiří. Úvod do preparativní anorganické chemie. 3. vyd. Praha: SNTL - Nakladatelství technické literatury, 1974, 373 s. info
• TANAKA, John and Steven L. SUIB. Experimental Methods in Inorganic Chemistry. New Jersey: Prentice Hall, 1999, 393 pp. ISBN 0-13-841909-4. info

Teaching methods

The education is realized as a laboratory course, which takes place once a week and the laboratory course covers basic laboratory operations, which are practised on the real anorganic and organic syntheses. In the end the students have to work out the laboratory reports.

Assessment methods

The course can also be completed outside the examination period. The course is taught annually. The course is taught: every week.

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Listed among pre-requisites of other courses

• C2720 Organic Chemistry - laboratory course
  (C4221||C1100||C1600)&&!C2200  
• C6190 Advanced laboratory course of inorganic chemistry.
  C2200  

• Enrolment Statistics (Spring 2012, recent)
  
• Permalink: https://is.muni.cz/course/sci/spring2012/C2200