Bi0195 Master state exam from Anthropogenetics

Faculty of Science
Spring 2015
Extent and Intensity
0/0/0. 0 credit(s). Type of Completion: SZK (final examination).
Teacher(s)
doc. RNDr. Eva Drozdová, Ph.D. (lecturer)
Guaranteed by
prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: doc. RNDr. Eva Drozdová, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Master degree examen. After passing the students will receive master degree.
Syllabus
  • Human evolution – from paleocene primates to H. sapiens sapiens. Basics of systematice and taxonomy. Application of modern methods in antropology: genetic methods, aDNA and its specifyty, paleoserology, paleodemografy, paleopathology, diet reconstruction, migrations, research of mummies.
  • Biological variability of human populations - individual and evolution adaptations. Study of polymorphic traits. Principles of population genetics. Race systems and rasism.
  • Functional and clinical anthropologie - determination of motorical abilities, evalutation of locomotor system. Inheritance of body composition. Somatic indieces, relationships between individual somatic parameters. Basic anthropological methods used in clinical praxis. Diagnostics of patological growth and develoment. Importance of anthropological standards in clinical praxis. Antropological screening. Genetic diagnostics of inherited deffects. Basic nutriensts, mineral and vitamines. Diet arrangement, consumer baskets and nutritional stereotypes.
  • Nucleic acids, their structure, biological function and interactions with proteins. Gen, genetic information, genetic code. Prokaryotic and eukaryotic genom. Replication, transcription, translation. Posttranscriptional and posttranslational changes in eukaryota. Regulation of genomic expresion. Basic levels of regulation and its principles.
  • Molecular mechanisms of signalistion. General principles of cell signalisation. Types of receptors for receiving signals.
  • Molekular ground of changes of genetic information and structure of genomes. Molekular ground of mutations. Reparation of mutation changed DNA. Molecular ground of recombination. Transpostion.
  • Basic methods of study of genom. Enzymatic changes of nucleic acids vitro. Methods of separation of nucleic acids and proteins. Sequencing DNA. Construction of physical and genetical map of genom. Polymerase chain reaction. Hybridistion of nucleic acids. Method for determining of gemomic polymorhpism: method without amplifiction, methods using hybridisation, methods PCR. Cloning DNA basic types of vectors. Genomic and gene libraries. Principles of bioinformatics.
  • Mendel's principles. Fundamentals of genetic variability. Chromozom fundamentals of basic principles of genetics - meiosis. Interaction of aleles in the same gene a interaction of more genes. Influence of environment on gene expresion.
  • Chromozomal determination of sex. Genotypic determination of sex. Inheritance of genes fixed at sex chromosomes.
  • Charakteristics of human cariotype. Euploidy, aneuploidy, chromosomal aberactions, gen mutations. Mutagenes.
  • Genetic foundation of quantitative traits. Analysis of quantitative traits, heritability.
  • Genetic structure of populations and its charackteristics. Hardy - Weinberg princip, testing its validity.
  • Genetic conditioned patological status in human.
Literature
  • ŠMARDA, Jan. D.P. Snustad a M.J. Simmons: Genetika. Brno: Masarykova univerzita, 2010, 3 pp. Universitas 43. ISSN 1211-3387. info
  • RIEGEROVÁ, Jarmila, Miroslava PŘIDALOVÁ and Marie ULBRICHOVÁ. Aplikace fyzické antropologie v tělesné výchově a sportu : (příručka funkční antropologie). 3. vyd. Olomouc: Hanex, 2006, 262 s. ISBN 8085783525. info
  • MIELKE, James H., Lyle W. KONIGSBERG and John RELETHFORD. Human biological variation. New York, N.Y.: Oxford University Press, 2006, xiv, 418. ISBN 0195188713. info
  • Antropologie :příručka pro studium kostry. Edited by Milan Stloukal. 1. vyd. Praha: Národní muzeum, 1999, 510 s. ISBN 80-7036-101-8. info
Teaching methods
final examination
Assessment methods
oral examen
Language of instruction
Czech
Further Comments
Study Materials
The course is taught each semester.
The course is also listed under the following terms Spring 2013, Spring 2014, Autumn 2014, Autumn 2015, Spring 2016, Autumn 2016, Spring 2017, autumn 2017, spring 2018, Autumn 2018, Spring 2019, Spring 2020, Autumn 2020, Spring 2021, autumn 2021, Spring 2022, Autumn 2022, Spring 2023, Autumn 2023, Spring 2024, Autumn 2024, Spring 2025.
  • Enrolment Statistics (Spring 2015, recent)
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