Bi6384 Advanced and Applied Immunology

Faculty of Science
Spring 2017
Extent and Intensity
2/0/0. 2 credit(s) (plus extra credits for completion). Type of Completion: graded credit.
Teacher(s)
prof. RNDr. Jaroslav Turánek, DSc. (lecturer), doc. RNDr. Martin Vácha, Ph.D. (deputy)
MVDr. Mgr. Monika Dušková, Ph.D. (assistant)
Guaranteed by
doc. RNDr. Antonín Lojek, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: doc. RNDr. Antonín Lojek, CSc.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science
Prerequisites (in Czech)
Bi5220 Immunology
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
The concept of this course is introduction into the very complex science like vaccinology and related disciplines. The aim of this course is to obtain basic information and general knowledge about application fields of immunology for prevention and treatment of infectious diseases and cancer. The stress is put on showing the main connection between various scientific disciplines like e.g. immunology, biochemistry, genetics, molecular biology, chemistry and physical-chemistry, material sciences, pharmacology, human and veterinary medicine, etc. Some sociological, historical and political aspects of vaccination are introduced to complete the view of this field. At the end of the course students should be able to understand and explain principles of various types of vaccines and immunotherapeutical approaches, apply information on pathogen and its interaction with the host for suggestion of efficient strategy for development of particular vaccine or immunotherapy.
Syllabus
  • Historical, social, legislative and ethic aspects of immunotherapy and vaccination, vaccination strategies, anti-vaccination movement. Literature – books and journals. Veterinary and human vaccination campaign, vaccination programs. Epizootology and transfer of pathogens, examples of human and veterinary diseases. Mucosal immunity and its relation to vaccination Antimicrobial peptides of natural and synthetic origin, antiviral drugs. Mechanisms of immune response towards antigens. Vaccines – live and attenuated, recombinant, subunit and genetic vaccines, adjuvans, nano- and microcarriers (polymers, liposomes, dendrimers, microbubles). Cell therapy and cell-based vaccines. Immunogenetics, immunopharmacology, neuroimmunology. Clinical immunology.
Literature
  • KREJSEK, Jan and Otakar KOPECKÝ. Klinická imunologie. 1. vyd. Hradec Králové: NUCLEUS HK, 2004, 941 s. ISBN 808622550X. info
  • TOMAN, Miroslav. Veterinární imunologie. 1. vyd. Praha: Grada, 2000, 413 s. ISBN 8071697273. info
  • HOŘEJŠÍ, Václav and Jiřina BARTŮŇKOVÁ. Základy imunologie. 3. vyd. Praha: Triton, 2005, 279 s. ISBN 8072546864. info
  • Immunobiology : the immune system in health and disease. Edited by Charles Janeway. 6th ed. New York, N.Y.: Garland Science, Taylor & Francis Group, 2005, xxiii, 823. ISBN 0815341016. info
Teaching methods
Lectures and presentations by Czech specialists.
Assessment methods
Graded credit. The stress is put on preparation of short lecture (10-15 min, Power-Point) on complex immunological/pharmaceutical/medicinal topics, clear and well focused presentation (Czech, English and Slovak languages are acceptable) and short discussion.
Language of instruction
Czech
Further Comments
The course is taught annually.
Listed among pre-requisites of other courses
The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2011 - only for the accreditation, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, spring 2012 - acreditation, Spring 2013, Spring 2014, Spring 2015, Spring 2016, spring 2018, Spring 2020, Spring 2023, Spring 2024.
  • Enrolment Statistics (Spring 2017, recent)
  • Permalink: https://is.muni.cz/course/sci/spring2017/Bi6384