Bi9906 Outbound Development Biology Seminar

Faculty of Science
Spring 2022
Extent and Intensity
2/0/0. 2 credit(s) (plus extra credits for completion). Type of Completion: k (colloquium).
Teacher(s)
prof. Mgr. Vítězslav Bryja, Ph.D. (lecturer)
doc. RNDr. Marcela Buchtová, Ph.D. (lecturer)
RNDr. Vendula Hlaváčková Pospíchalová, Ph.D. (lecturer)
RNDr. Pavel Krejčí, Ph.D. (lecturer)
Guaranteed by
prof. Mgr. Vítězslav Bryja, Ph.D.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Alois Kozubík, CSc.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
there are 8 fields of study the course is directly associated with, display
Course objectives
Main objectives of the course are: - to apply the basic knowledge about molecular mechanism of development onto specific developmental process - to learn and discuss how developmental biology contributes to disease treatment and regenerative medicine Student passing this course will be able to apply the knowledge of molecular mechanisms controlling animal development into associated fields such as regenerative, reproductive and oncology-related medicine.
Learning outcomes
Student passing this course will be able to apply the knowledge of molecular mechanisms controlling animal development into associated fields such as regenerative, reproductive and oncology-related medicine.
Syllabus
  • 1. Summary of basic findings and information from „Animal developmental physiology I“ 2. Morphogenesis – cell adhesion, gastrulation, neural crest formation, cell migration. Cell differentiation: universal and tissue-specific regulators, external signals, chemical and structural modification of DNA. 3. Development of nervous system – general features, main cell types, anterior-posterior patterning of neural tube, dorsal-ventral patterning of neural tube, development of neurons and glia 4. Development of selected mesodermal organs (muscle, bone, cartilage): somite and muscle development, cartilage and bone development, development of limb. Developmental defects. 5. Development of endodermal organs: endoderm determination, pancreas. 6. Development of blood and immune system. Molecular mechanisms and defects -various types of leukemia. 7. Stem cells. Importance for development and tissue homeostasis. Relation to tumor-formation and metastasis. Embryonal and cancer stem cells. 8. Activation of developmental mechanisms in the adult. Activation in regeneration and tumor process. Molecular mechanisms regulating development activated in tumors. 9. Developmental processes in regenerative medicine. Targeted differentiation and stem cell transplantation. The current status – possibilities, limitations and hopes. 10. , 11. External speakers.
Literature
  • GILBERT, Scott F. Developmental biology. Edited by Susan R. Singer. 8th ed. Sunderland, Mass.: Sinauer Associates, 2006, xviii, 817. ISBN 087893250X. info
  • SLACK, J. M. W. Essential developmental biology. 2nd ed. Oxford: Blackwell, 2006, ix, 365. ISBN 1405122161. info
  • WILT, Fred H. and Sarah HAKE. Principles of developmental biology. New York, N.Y.: W.W. Norton & Company, 2004, xxiii, 430. ISBN 0393974308. info
  • BROWDER, Leon W., Carol A. ERICKSON and William R. JEFFERY. Developmental biology. 3rd ed. Philadelphia: Saunders College Publishing, 1991, 754 s. ISBN 0-03-013514-1. info
Teaching methods
lectures, class discussions and group projects
Assessment methods
Teaching methods: lectures, class discussion, group projects, presentations by professionals in the sector Colloquium requirements: active participation on the course, presentation of the student project
Language of instruction
Czech
Further comments (probably available only in Czech)
The course is taught annually.
The course is taught: in blocks.
Information on course enrolment limitations: Předmět je primárně určen pro studenty magisterských as doktorských studijních programů. Na předmět se vztahuje povinnost registrace, bez registrace může být znemožněn zápis předmětu!
The course is also listed under the following terms Spring 2011 - only for the accreditation, Spring 2009, Spring 2010, Spring 2011, Spring 2012, spring 2012 - acreditation, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021.
  • Enrolment Statistics (recent)
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