C2022 Organic Chemistry I - Seminar

Faculty of Science
Spring 2025
Extent and Intensity
0/2/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: z (credit).
In-person direct teaching
Teacher(s)
doc. Mgr. Kamil Paruch, Ph.D. (lecturer)
doc. Mgr. Jakub Švenda, PhD. (lecturer)
RNDr. Slávka Janků, Ph.D. (seminar tutor)
Mgr. Jaromír Literák, Ph.D. (seminar tutor)
Guaranteed by
RNDr. Slávka Janků, Ph.D.
Department of Chemistry – Chemistry Section – Faculty of Science
Supplier department: Department of Chemistry – Chemistry Section – Faculty of Science
Prerequisites
NOW( C2021 Organic Chemistry I )|| C2021 Organic Chemistry I
Knowledge of general and inorganic chemistry.
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
there are 15 fields of study the course is directly associated with, display
Course objectives
The aim of this special seminar course is to exercise the topics introduced in lecture Organic Chemistry I on practical examples. The topics involve basic drafts such as principles of chemical nomenclature, principles of stereochemistry, major study methods of the structure of organic compounds, theories of acidity and basicity. Students will be introduced to the major types of organic chemistry reactions such as ionic, radical, redox and some orbital steering reactions.
Learning outcomes
The Organic Chemistry I course graduates will be able to understand basic drafts of organic chemistry such as acidity and basicity, equilibrium of chemical reactions etc.;
They will be able to understand and describe mechanism of basic types of organic chemistry reactions;
On the bases of the gained knowledge they will be able to explain differences in reactivity between individual groups of organic compounds;
They will have created necessary foundation for graduating the followed course Organic Chemistry II, where they use obtained knowledge for planning complicated organic compounds syntheses.
Syllabus
  • 1. The scope of Organic Chemistry. Drawing organic molecules. Basic principles of nomenclature. Aliphatic and cyclic skeletons, hierarchy of functional groups. 2. Carbon atom bonding. Hybridization of atomic orbitals, bond angles. Electron structure of molecules, sigma and pi-bond. Molecular orbitals, conjugation and delocalization. Mesomeric effect and resonance structures. Polarity and polarizability, charge distribution in molecules. 3. Basics of organic stereochemistry. Drawing organic molecules. Isomers and stereoisomers. Conformation and configuration. Geometric isomerism of alkenes and cycloalkanes. Conformation of ethane, butane and cyclohexane. Symmetry and chirality. Cahn-Ingold-Prelog nomenclature. Fischer projection. 4. Organic structures determination methods (MS,NMR, IR, UV-Vis). 5. Chemical reactions. Homolysis and heterolysis. Classification of organic reactions according to structural change (S-A-E-R). Reaction mechanism - "Arrow pushing". Depiction of organic reaction. Kinetics and thermodynamics. 6. Acids and Bases. Broensted theory. Chemical equilibrium. pH, pKa. Strength of (organic) acids and bases. Electrophiles and nucleophiles. Lewis theory. Hard and Soft Acids and Bases (HSAB). 7. Oxidation reduction reactions.SN1 and SN2 mechanisms 8. Nucleophilic subtitution and elimination reactions (halogen derivatives, alcohols, amines). Reaction kinetics, rate determining reaction step, carbocations stability, reaction stereospecifity. 9. Nucleophilic addition on cabonyl group. Michael addition, keto-enol tautomerism, Adition-elimination mechanism. 10. Electrophilic addition reactions. Alkenes, alkynes. Radical addition and polymerization. Radical substitution. 1,2- and 1,4-addition reactions pf conjugated dienes. 11. Aromaticity. Electrophilic aromatic substitution. Nucleophilic substituon. 12. Reaction with conservation of orbytal symmetry. Pericyclic reactions. Diels-Alder rection.
Literature
  • Potáček, Milan - Mazal, Ctibor - Janků, Slávka. Řešené příklady z organické chemie. 1. vyd. Brno : Masarykova univerzita v Brně, 2005. 243 s. ISBN 80-210-2274-4. info
  • POTÁČEK, Milan and Eduard NOVÁČEK. Organická chemie : příručka řešených příkladů. Edited by Slávka Janků. 1. vyd. Brno: Masarykova univerzita, 1997, 201 s. ISBN 8021016728. info
  • MCMURRY, John. Organická chemie. Translated by Jaroslav Jonas. Vyd. 1. Praha: Vysoká škola chemicko-technologická v Praze, 2007, 1 sv. ISBN 9788070806371. info
  • LITERÁK, Jaromír. Sbírka řešených příkladů k semináři z organické chemie (Collection of Excercises in Organic Chemistry). 1. vydání. Brno: Masarykova univerzita, 2012, 308 pp. ISBN 978-80-210-5810-1. info
Teaching methods
class discussions upon the corresponding lecture topics
Assessment methods
During the course several tests are written and their good results are the conditions for credits obtaining.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course is taught annually.
The course is taught: every week.
The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2011 - only for the accreditation, Spring 2000, Spring 2001, Spring 2002, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, spring 2012 - acreditation, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024.
  • Enrolment Statistics (recent)
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