C5321 Theoretical Concepts of Nuclear Magnetic Resonance

Faculty of Science
Spring 2025
Extent and Intensity
0/2/0. 2 credit(s). Type of Completion: z (credit).
In-person direct teaching
Teacher(s)
prof. Mgr. Lukáš Žídek, Ph.D. (lecturer)
Mgr. Pavel Kadeřávek, Ph.D. (assistant)
Guaranteed by
prof. Mgr. Lukáš Žídek, Ph.D.
National Centre for Biomolecular Research – Faculty of Science
Supplier department: National Centre for Biomolecular Research – Faculty of Science
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
there are 9 fields of study the course is directly associated with, display
Course objectives
The course objective is to acquire technical skills allowing the student to derive relations important for understanding NMR spectroscopy and to analyse NMR experiments.
Learning outcomes
At the end of the course, the students will be able to
1. derive fundamental relations of the physical description of NMR spectroscopy
2. apply mathematical procedures to actual physical problems.
3. analyze basic NMR experiments at the level of the vector model and of the product operator formalism.
4. identify parameters determining results of the experiments.
Syllabus
  • 1. Magnetic moment of a current loop
  • 2. Precession
  • 3. Polarization
  • 4. Loss of coherence
  • 5. Fourier transform of ideal and finite signal
  • 6. Relativistic quantum mechanics
  • 7. Liouville-von Neumann equation
  • 8. One-pulse experiment, dipolar coupling
  • 9. Relaxation due to dipolar coupling
  • 10. NOESY
  • 11. Evolution with scalar coupling, spin echoes
  • 12. HSQC
Literature
  • BROWN, Keith C. Essential mathematics for NMR and MRI spectroscopists. Cambridge, UK: Royal Society of Chemistry, 2017, xvi, 867. ISBN 9781782627975. info
  • KEELER, James. Understanding NMR spectroscopy. 2nd ed. Chichester: John Wiley and Sons, 2010, xiii, 511. ISBN 9780470746080. info
  • LEVITT, Malcolm H. Spin dynamics : basics of nuclear magnetic resonance. 2nd ed. Chichester, England: John Wiley & Sons, 2008, xxv, 714. ISBN 9780470511176. info
  • Protein NMR spectroscopyprinciples and practice. Edited by John Cavanagh. 2nd ed. Boston: Academic Press, 2007, xxv, 885 p. ISBN 012164491X. info
Teaching methods
problem solving, class discussion, homework
Assessment methods
homeworks
Language of instruction
English
Further Comments
The course can also be completed outside the examination period.
The course is taught annually.
The course is taught: every week.
The course is also listed under the following terms Autumn 1999, Autumn 2016, autumn 2017, Autumn 2018, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024.
  • Enrolment Statistics (recent)
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