C8545 Developmental biology

Faculty of Science
Spring 2025
Extent and Intensity
2/0/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
In-person direct teaching
Teacher(s)
doc. RNDr. Jan Hejátko, Ph.D. (lecturer)
Guaranteed by
doc. RNDr. Jan Hejátko, Ph.D.
National Centre for Biomolecular Research – Faculty of Science
Contact Person: doc. RNDr. Jan Hejátko, Ph.D.
Supplier department: National Centre for Biomolecular Research – Faculty of Science
Prerequisites
( Bi4010 Essential molecular biology || Bi4020 Molecular biology )
Advantage is the knowledge of the topics of the basic lectures from molecular biology and genetics.
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
there are 17 fields of study the course is directly associated with, display
Course objectives
The goal of the course is making the student familiar with basic principles of ontogenesis in animals (Xenopus, Drosophila, mouse, chicken, human), as well as in plants (mostly Arabidopsis). IN the closing lectures are being discussed fundamental developmental principles involved e.g. in the regulation of gene expression, morphogenesis and organogenesis in animals and plants.
Learning outcomes
At the end of the course, the student should understand the basic principles of development of selected model organisms, animals and plants. Student will be able to identify basic differences and common developmental principles of organisms and (s)he will be able to demonstrate them on the basic developmental processes of insects, amphibians, mammals and plants. Student will get an overview about the developmental mechanisms at the organism, cell and particularly molecular levels.
Syllabus
  • 1. Lesson: Overview of development, repetitorium of basic terms, gametogenesis, fertilization and lineage tracing.
  • 2. Lesson: Oogenesis and early development of Drosophila.
  • 3. Lesson: Early development of amphibians and amniotes.
  • 4. Lesson: Vertebrate organogenesis, development of ectodermal structures.
  • 5. Lesson: Vertebrate organogenesis, development of mesodermal and endodermal structures.
  • 6. Lesson: Plant reproduction, changing of generations, initiation of flowering, flower development, gametogenesis, fertilization.
  • 7. Lesson: Embryogenesis of seed plants
  • 8. Lesson: Postembryonic de novo organogenesis in plants, concept of meristems. Shoot development, SAM, phyllotaxis. Root development, RAM, lateral root formation. Shoot and root vascular tissue development. Hormonal interactions in the de novo organogenesis in plants.
  • 9. Lesson: Morphogenesis in animals, cellular associations, environment and behaviors, tissue interactions and morphogenesis. Morphogenesis in plants, leaf development, role of auxin distribution and its interaction with CK in the morphogenesis in plants
  • 10. Lesson: Regulation of gene expression. The levels of regulation of gene expression in development of animals and plants, RNA interference.
Literature
  • WILT, Fred H. and Sarah HAKE. Principles of developmental biology. New York, N.Y.: W.W. Norton & Company, 2004, xxiii, 430. ISBN 0393974308. info
Teaching methods
Lectures and presenations of image materials including video clips and supplemented by internet learning resources.
Assessment methods
Type of lectures: The lectures are facultative, however, the presence of students is highly desirable for complete understanding of developmental principles; the teaching materials are available on-line. Type of exam: Written exam. The test consists from 30 questions, each valued up to 4 points, thus the total maximum is 120 points. Evaluation criteria of the examination test are as follows: 120-111 points (100-93%) A, 110-102 points (92-85%) B, 101-90 points (84-75%) C, 89-78 points (74-65%) D, 77-66 points (64-55%) E, <66 points (<55%) F.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course is taught annually.
The course is taught: every week.
The course is also listed under the following terms Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024.
  • Enrolment Statistics (recent)
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