aVLBC0422t Biochemistry II Laboratory Medicine - seminar

Faculty of Medicine
spring 2025
Extent and Intensity
0/1.3/0. 2 credit(s). Type of Completion: z (credit).
In-person direct teaching
Teacher(s)
doc. RNDr. Josef Tomandl, Ph.D. (seminar tutor)
doc. RNDr. Jiří Dostál, CSc. (seminar tutor)
MUDr. Michaela Králíková, Ph.D. (seminar tutor)
RNDr. Hana Paulová, CSc. (seminar tutor)
Mgr. Jiří Slanina, Ph.D. (seminar tutor)
prof. RNDr. Eva Táborská, CSc. (seminar tutor)
Mgr. Jana Gregorová, Ph.D. (assistant)
doc. PharmDr. Jiří Kos, Ph.D. (assistant)
doc. Mgr. Ondřej Peš, Ph.D. (assistant)
Mgr. Marie Tomandlová, Ph.D. (assistant)
Guaranteed by
doc. RNDr. Josef Tomandl, Ph.D.
Department of Biochemistry – Theoretical Departments – Faculty of Medicine
Contact Person: MUDr. Michaela Králíková, Ph.D.
Supplier department: Department of Biochemistry – Theoretical Departments – Faculty of Medicine
Prerequisites (in Czech)
aVLBC0321s Biochemistry I - seminar && aVLFY0321c Physiology I - practice && aVLFY0321s Physiology I - seminar
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The course combines theoretical biochemistry knowledge with clinical applications.
The aim of the course is to provide information about the importance of clinical biochemistry and its implementation, factors affecting laboratory results, the importance of biological variability and its application in the evaluation of results, diagnostic effectiveness of laboratory tests. The aim of the course is also to acquaint students in more detail with some specific biochemical tests, such as disorders of carbohydrate metabolism, liver and heart disease, assessment of renal function, and examination of urine and cerebrospinal fluid.
Learning outcomes
After completing the course, the student will be familiar:
- have an idea of the importance of clinical-biochemical examinations, their implementation, factors influencing the results and their control.
- have an idea of biological variability, evaluation of results and diagnostic effectiveness of laboratory tests.
- familiar with biochemical examinations in liver diseases, carbohydrate metabolism disorders and cardiovascular diseases.
- familiar with examinations of renal function, acid-base balance and its disorders, examination of urine and cerebrospinal fluid.
Syllabus
  • Factors influencing results of laboratory examinations, preanalytical factors. Collection and processing of blood. Communicating results of biochemical examination
  • Analytical factors influencing results of laboratory examinations. Validation and interpretation of results, critical difference. Diagnostic accuracy.
  • Biochemical examinations in diabetes mellitus. Laboratory control of the disease.
  • Biochemical investigations of lipid metabolism. Atherosclerosis risk factors.
  • Laboratory tests in myocardial infarction.
  • Biochemical examinations of liver diseases, laboratory diagnostics of hyperbilirubinemia. Laboratory examination of specific liver diseases.
  • Laboratory examination of the gastrointestinal tract.
  • Urine sampling and collection. Physical and chemical examination of urine.
  • Examination of glomerular filtration. Examination of renal tubular function. Examination for urolithiasis.
  • Cerebrospinal fluid analysis.
Literature
    required literature
  • Study materials for the course in IS MU.
    recommended literature
  • Rajdl. D. a kol. Clinical biochemistry (e-book, formats: .pdf, .epub, .mobi) 1st ed. Prague, Karolinum Press, 2016, 426 s. ISBN: 978-80-246-3497-5. Download: https://karolinum.cz/en/books/rajdl-clinical-biochemistry-17096
Teaching methods
Seminars, active discussions of problems, biochemical case reports.
Assessment methods
Credit. Conditions for giving the course-unit credit:
1) completion of all seminars and 2) completion of in-term tests.
Failure to meet the requirements of in-term tests requires a resit test, which may be repeated only once.
Detailed conditions are published in Study materials posted under the course/Interactive Syllabus.
Language of instruction
English
Further comments (probably available only in Czech)
The course is taught annually.
The course is taught: every week.
General note: Successful completion of the course is a condition for access to the exam in the course aVLBC0422p.
Information on the extent and intensity of the course: 19.5.
Teacher's information
Information about seminars, the conditions for giving the course-unit credit, and the syllabus are available in the IS MU in the course-related instructions.
Consultations are possible after a personal arrangement with the teacher.
The course is also listed under the following terms spring 2023, spring 2024.
  • Enrolment Statistics (spring 2025, recent)
  • Permalink: https://is.muni.cz/course/med/spring2025/aVLBC0422t