EMEM0731p Embryology

Faculty of Medicine
autumn 2024
Extent and Intensity
2/0/0. 4 credit(s). Type of Completion: zk (examination).
Teacher(s)
doc. MVDr. Aleš Hampl, CSc. (lecturer)
PharmDr. Zuzana Holubcová, Ph.D. (lecturer)
Drahomíra Kyjovská (assistant)
MUDr. Eva Mecová (assistant)
Guaranteed by
doc. MVDr. Aleš Hampl, CSc.
Department of Histology and Embryology – Theoretical Departments – Faculty of Medicine
Supplier department: Department of Histology and Embryology – Theoretical Departments – Faculty of Medicine
Timetable
Wed 11:00–12:40 F01B1/126
Prerequisites
EMAR0511p EMAD0611p
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The goal of the course is for students to have a thorough understanding of female germ cell biology and to be able to implement this knowledge into clinical practice.
Learning outcomes
Graduates of the course will have a comprehensive and thorough overview of the biology of female germ cells.
Syllabus
  • - Origin, characterization, migration and proliferation of primordial germ cells - - Mitosis and meiosis, homologous recombination, oocyte maturation, chromosomal segregation, disorders of gametogenesis (azoospermia, aneuploidy of eggs) - - Oogenesis and folliculogenesis (oocyte-follicular cell interaction, control of dormancy and activation of primordial follicles, follicle growth and selection, importance of atresia), experimental approaches in the management of folliculogenesis disorders - - Molecular mechanism of meiotic arrest (prophase I), oocyte maturation and MII arrest, - - Molecular mechanisms and disorders of ovulation, physiology and pathophysiology of the corpus luteum - - Morphology and ultrastructure of the oocyte, morphological abnormalities and their clinical significance, in vitro aging) - - Role of the cytoskeleton during oocyte development - - Oocyte polarity and role of maternal factors in somatic cell nuclear reprogramming - - Regulation of transcription and translation during oogenesis, oocyte metabolism - - Inheritance and prevention of mitochondrial diseases - - Influence of environmental factors on oocyte quality
Literature
    recommended literature
  • Coward K., Wells D.: Textbook of Clinical Embryology, 1st ed., Cambridge 2013.
  • Trounson A, Gosden R, Eichenlaub-Ritter: Biology and Pathology of the Oocyte. 2nd ed., Cambridge 2013. Gardner DK, Sakkas D, Seli E, Wells D: Human gametes and preimplantation Embryos. 1st ed. New York 2013.
  • In vitro fertilization. Edited by Kay Elder - Brian Dale. 2nd ed. New York: Cambridge University Press, 2000, xii, 310 p. ISBN 0521778638. info
Teaching methods
lecture
Assessment methods
oral exam the condition for admission to the exam is participation in lectures by external lecturers
Language of instruction
Czech
Follow-Up Courses
Further comments (probably available only in Czech)
Study Materials
Information on the extent and intensity of the course: 30.
The course is also listed under the following terms autumn 2023.
  • Enrolment Statistics (recent)
  • Permalink: https://is.muni.cz/course/med/autumn2024/EMEM0731p