aVLBI0222p Biologie II - přednáška

Lékařská fakulta
jaro 2016
Rozsah
1/0. 4 kr. Ukončení: zk.
Vyučující
Mgr. Kateřina Cetkovská, Ph.D. (přednášející)
prof. Ing. Petr Dvořák, CSc. (přednášející)
doc. Mgr. Lumír Krejčí, Ph.D. (přednášející)
RNDr. Pavel Krejčí, Ph.D. (přednášející)
Mgr. Vladimír Rotrekl, Ph.D. (přednášející)
prof. MUDr. Iva Slaninová, Ph.D. (přednášející)
prof. MUDr. David Šmajs, Ph.D. (přednášející)
RNDr. Mário Špírek, PhD. (přednášející)
Mgr. Stjepan Uldrijan, CSc. (přednášející)
Mgr. Kateřina Vopěnková, Ph.D. (přednášející)
doc. Yuh-Man Wadeley, Doctor of Philosophy (přednášející)
Jana Růžičková (pomocník)
Mgr. Martina Vráblíková (pomocník)
Garance
prof. Ing. Petr Dvořák, CSc.
Biologický ústav – Teoretická pracoviště – Lékařská fakulta
Kontaktní osoba: Mgr. Kateřina Cetkovská, Ph.D.
Dodavatelské pracoviště: Biologický ústav – Teoretická pracoviště – Lékařská fakulta
Rozvrh
St 13:00–13:50 B11/234
Předpoklady
aVLBI0121c Biologie I - cvičení && aVLBI0121s Biologie I - seminář
Knowledge of high-school biology and all previous lectures and practical classes of the subject are prerequisities for studying the course. Expected knowledge for each lecture is specified in the course syllabus. Literature recomended to study before each lecture is detailed in the interactive syllabus of the course.
Omezení zápisu do předmětu
Předmět je určen pouze studentům mateřských oborů.
Mateřské obory/plány
Cíle předmětu
After completion of the course student: understands elementary cellular processes and processes taking place during development of a human body; comprehends the complexity of intercellular communication and mutual regulation of individual cells in a multicellular organism; is able to deduce and explain the difference between healthy and pathologically-working cell; is able to express basic coherence between malfunction in cellular processes and development of diseases, especially hereditary diseases, cancers or developmental defects; can explain and justify action of some therapeutics with emphasis on modern medicine. Student is also able to apply this knowledge and skills in other subject, especially physiology, pathophysiology and human genetics.
Osnova
  • Week 1: 22.2. – 26.2. 2014
  • Growth factors and signal transduction in development and disease (Mgr. Pavel Krejčí, Ph.D.)
  • Week 2: 29.2. – 4.3.
  • Biology and use of stem cells in disease modelling and cell therapy (prof. Ing. Petr Dvořák, CSc.)
  • Week 3: 7.3. – 11.3.
  • Cell differentiation and tissue engineering (prof. Ing. Petr Dvořák, CSc.)
  • Week 4: 14.3. – 18.3.
  • Genome instability - from molecular mechanisms of damage and DNA repair to clinical implications (doc. Mgr. Lumír Krejčí, Ph.D)
  • Week 5: 21.3. – 25.3.
  • Introduction to cancer biology (Mgr. Stjepan Uldrijan, CSc.)
  • Week 6: 28.3. – 1.4.
  • Oncogenes and oncoviruses in cancer transformation (Mgr. Stjepan Uldrijan, CSc.)
  • Week 7: 4.4. – 8.4.
  • Tumour suppressor genes - implications for diagnostics and therapy (Mgr. Stjepan Uldrijan, CSc.)
  • Week 8: 11.4. – 15.4.
  • Paradigm of cancer stem cells (doc. MUDr. Iva Slaninová, Ph.D.)
  • Week 9: 18.4. – 22.4.
  • Molecular principle of genetically determined diseases (doc. MUDr. Iva Slaninová, Ph.D.)
  • Week 10: 25.4. – 29.4.
  • Objectives and strategies of molecular therapy (doc. MUDr. Iva Slaninová, Ph.D.)
  • Week 11: 2.5. – 6.5.
  • Genomics and other omics in current biomedicine (prof. MUDr. David Šmajs, Ph.D.)
  • Week 12: 9.5. – 13.5.
  • Human microbiome (prof. MUDr. David Šmajs, Ph.D.)
  • Week 13: 16.5. – 20.5.
  • Bioinformatics in medicine - from molecules to populations (Mgr. Vladimír Rotrekl, Ph.D.) - groups not having dissections clashing with the lecture
  • Week 14: 23.5. – 72.5.
  • Bioinformatics in medicine - from molecules to populations (Mgr. Vladimír Rotrekl, Ph.D.) - groups not having dissections clashing with the lecture
Literatura
    povinná literatura
  • Essential cell biology. Edited by Bruce Alberts. 3rd ed. New York: Garland Science, 2009, 1 sv. ISBN 9780815341307. info
  • Medical genetics at a glance. Edited by D. J. Pritchard - Bruce R. Korf. 3rd ed. Chichester, England: Wiley-Blackwell, 2013, 1 online r. ISBN 9781118689028. info
    doporučená literatura
  • HARDIN, Jeff, Gregory BERTONI a Lewis J. KLEINSMITH. Becker's world of the cell. 8th ed. Boston: Benjamin Cummings, 2012, xxviii, 79. ISBN 9780321709783. info
  • LODISH, Harvey F. Molecular cell biology. 6th ed. New York, N.Y.: W.H. Freeman and Company, 2008, xxxvii, 11. ISBN 9780716776017. info
  • SNUSTAD, D. Peter a Michael J. SIMMONS. Principles of genetics. 5th ed. Hoboken: John Wiley & Sons, Inc, 2009, xix, 823. ISBN 9780470388259. info
  • WEINBERG, Robert A. The biology of cancer. Second edition. London: Garland Science, 2013, xx, 876. ISBN 9780815345282. info
  • WOLPERT, L. Principles of development. 2nd ed. Oxford: Oxford University Press, 2002, xxv, 542. ISBN 0198792913. info
    neurčeno
  • CAMPBELL, Neil A. Biology. Edited by Jane B. Reece. 7th ed. San Francisco: Pearson/Benjamin Cummings, 2005, xl, 1231. ISBN 080537146X. info
Výukové metody
lecture
Metody hodnocení
Subject is completed with a written examination test, based on knowledge of all topics from both semesters (lectures, seminars, practices). The exam test contains 100 questions with 1 correct answer. Negative marking is obtained for incorrect answers. For successful passing the exam, minimum 68 points out of 200 are needed.
Requirements for attendance at the exam: successful passing of the autumn semester’s lecture and seminar, and successfull completion of Biology-practices of both autumn and spring semester.
Students have to bring their valid ICIS card to prove their identity at the exam. For more information on the test see: https://is.muni.cz/auth/el/1411/jaro2016/aVLBI0222p/op/Exam_information_and_instructions_ENG.pdf
Lecture attendance is optional.
Vyučovací jazyk
Angličtina
Informace učitele
https://is.muni.cz/auth/el/1411/jaro2016/aVLBI0222p/index.qwarp
Knowledge of high-school biology and all previous lectures and practical classes of the subject are prerequisities for studying the course. Expected knowledge for each lecture is specified in the course syllabus. Literature recomended to study before each lecture is detailed in the interactive syllabus of the course:
https://is.muni.cz/auth/el/1411/jaro2016/aVLBI0222p/index.qwarp
The two required text books can be also read on computers in the university library:
Essential cell biology by Alberts to be found through e-prezencka https://kuk.muni.cz/?page=9&lang=english
Medical genetics at a glance by Pritchard to be found through http://discovery.muni.cz
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