APFYc Pathological physiology - practicals

Faculty of Medicine
spring 2019
Extent and Intensity
0/2/0. 2 credit(s). Recommended Type of Completion: z (credit). Other types of completion: zk (examination).
Teacher(s)
MUDr. Vendula Bartáková, Ph.D. (seminar tutor)
MUDr. Michal Jurajda, Ph.D. (seminar tutor)
MUDr. Jan Máchal, Ph.D. (seminar tutor)
prof. RNDr. Michal Masařík, Ph.D. (seminar tutor)
Mgr. Lukáš Pácal, Ph.D. (seminar tutor)
prof. MUDr. Anna Vašků, CSc. (seminar tutor)
Mgr. Katarína Chalásová, Ph.D. (assistant)
Věra Ježková (assistant)
Guaranteed by
prof. MUDr. Anna Vašků, CSc.
Department of Pathophysiology – Theoretical Departments – Faculty of Medicine
Contact Person: MUDr. Michal Jurajda, Ph.D.
Supplier department: Department of Pathophysiology – Theoretical Departments – Faculty of Medicine
Timetable of Seminar Groups
APFYc/01: each even Monday 16:00–20:00 B11/334
APFYc/02: each odd Monday 16:00–20:00 B11/334
APFYc/03: each even Monday 16:00–20:00 B11/334
APFYc/04: each odd Monday 16:00–20:00 B11/334
APFYc/05: each even Monday 16:00–20:00 B11/334
APFYc/06: each odd Monday 16:00–20:00 B11/334
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
After completing this subject the students will be able to explain possibilities of modern methodologies in medicine (ECG, ambulatory blood pressure monitoring, dopplerometry, molecular biology methodology, animal experiments and statistical evaluation of experimental data), specifically focused on experimental profile of Department of Pathophysiology-genetic background of complex diseases.
Learning outcomes
The student will explain the importance and principles of DNA Diagnostics to detect I/D polymorphism using PCR methodology, ACE
The student will explain the principle of ultrasound and dopplerometric examination of the blood vessels, the underlying pathology of peripheral vasculature (venous valvular insufficiency, ischemia, short circuits, steal syndromes)
The student interprets the continuous ECG record in experimental animal for some pathological conditions, will describe the findings on the record EKG
The student distinguishes ECG records in most commonly occurring arrhythmias
Student demonstrates knowledge of indications and principle 24 h-monitoring of blood pressure, physiological and pathological curves in   record
The student distinguishes between methods of testing blood pressure and heart rate, indications for ambulatory blood pressure monitoring (AMTK), the development of blood pressure and heart rate during load tests (isometric burden, exercise)
The student demonstrates the basic static and dynamic parameters surveyed during the spirometric examination and their relationship to pulmonary obstructive and restrictive diseases
The student demonstrates understanding of diagnosis of diabetes load test (oGTT) in an animal model experimentally induced diabetes (alloxan)
The student shall identify clinically relevant parameters for description of the status of nutrition (calorimetry, BMI, WHR index, the weight, the skin-fold thickness, bioimpedance, DEXA)
Syllabus
  • Pathophysiology as a branch of science. Principles and ethical principles of conducting experiments on animals. Processing of experimental data, the foundations of statistics.
  • Arythmology (seminar). Experimentally-induced renal failure- ECG picture of hyperkalemia.
  • Atherosclerosis (seminar). Experimentally induced atherosclerosis-reviews of remodeling of blood vessels. Doppler
  • An overview of the methods used in molecular biology   pathophysiology (demonstration of selected lab methods), the importance of DNA diagnostics-I/D polymorphism detection in   gene for ACE.
  • Eating disorders, body fat measurement device demonstration BODYSTAT
  • Spirometry. Essential hypertension, blood pressure and heart rate, and 24-hour ambulatory blood pressure monitoring. ECG-technical aspects
  • Diabetes mellitus-pathophysiology and diagnosis. Exp.-induced diabetes mellitus-glucose tolerance test card.
Literature
    recommended literature
  • KAŇKOVÁ, Kateřina, Dobroslav HÁJEK, Marcel HORKÝ, Lydie IZAKOVIČOVÁ HOLLÁ, Michal JURAJDA, Vladimír KOTALA, Jiří VÁCHA, Anna VAŠKŮ and Vladimír ZNOJIL. Patologická fyziologie pro bakalářské studijní programy (Pathophysiology for paramedical study programms). 1st ed. Brno: Masarykova univerzita v Brně, 2003, 161 pp. 1. vydání. ISBN 80-210-3112-3. info
Teaching methods
practicals in labs, discussion with the tutor, video with comments
Assessment methods
The credit is given according to attendance of practicals and pass of written test.
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
The course is taught annually.
General note: Skupiny 1, 2 budou absolvovat výuku v 1., 3., 5., 7., 9., 11. a 13. Skupiny 3, 4 v týdnech 2., 4., 6., 8., 10., 12. a 14.
Information on the extent and intensity of the course: 30.
The course is also listed under the following terms Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, Spring 2018, spring 2020, spring 2021, spring 2022, spring 2023, spring 2024, spring 2025.
  • Enrolment Statistics (spring 2019, recent)
  • Permalink: https://is.muni.cz/course/med/spring2019/APFYc