aZLBI0222c Biologie II - cvičení

Lékařská fakulta
jaro 2019
Rozsah
0/2/0. 30. 2 kr. Ukončení: z.
Vyučující
Ing. Lívia Eiselleová, Ph.D. (přednášející)
Mgr. Bohumil Fafílek, Ph.D. (cvičící)
Mgr. Hana Hříbková, Ph.D. (cvičící)
Master Alexandru Nită (cvičící)
Mgr. Markéta Nováková, Ph.D. (cvičící)
Mgr. Veronika Palušová, Ph.D. (cvičící)
MUDr. Martin Pešl, Ph.D. (cvičící)
Mgr. Petra Pospíšilová, Ph.D. (cvičící)
Mgr. Vladimír Rotrekl, Ph.D. (cvičící)
prof. MUDr. Iva Slaninová, Ph.D. (cvičící)
Mgr. Barbora Valčíková (cvičící)
Gretsen Velezmoro Jauregui, M.Sc., Ph.D. (cvičící)
Mgr. Kateřina Vopěnková, Ph.D. (cvičící)
Jana Růžičková (pomocník)
Garance
prof. Ing. Petr Dvořák, CSc.
Biologický ústav – Teoretická pracoviště – Lékařská fakulta
Kontaktní osoba: Mgr. Kateřina Vopěnková, Ph.D.
Dodavatelské pracoviště: Biologický ústav – Teoretická pracoviště – Lékařská fakulta
Rozvrh
St 14:00–14:30 B07/214, St 14:30–15:30 B07/214, St 14:30–15:30 B07/217, St 15:30–15:40 B07/214
Předpoklady
( aZLBI0121c Biologie I - cvičení || ZLBI0121c Biologie I - cvičení ) && ( aZC011 Zacházení s chemickými látkami || ZC011 Zacházení s chemickými látkami )
Omezení zápisu do předmětu
Předmět je určen pouze studentům mateřských oborů.
Mateřské obory/plány
Cíle předmětu
The main objectives of the course are:
- learning the methods of risk evaluation for hereditary diseases of various molecular background in patients based on family anamneses
- understanding the basic principles of gene engineering
- understanding and practicing the selected molecular methods used for examination of some cancers or hereditary and infectious diseases with regard to selection of appropriate therapy
Výstupy z učení
After completing the course the student will be able to:
- evaluate the risk of hereditary diseases of various molecular background in patients based on assigned family anamneses of the diseases
- describes the basic principles of genetic prognosis and genetic counselling
- suggest and perform basic molecular-genetic diagnostic examinations of some hereditary, tumour and infectious diseases (PCR, restriction digest, gel electrophoresis), and to interpret the obtained results
- explain selected basic techniques of gene engineering and their application in medicine, and, with knowledge of the used method, to select the clones of cells with an inserted gene
- explain the basic laboratory tests used in genetic toxicology and the overall use of genetic toxicology, and to interpret the results obtained by selected methods
Osnova
  • Week 1: Genetic disorders - gonosomal inheritance
  • Week 2: Extensions to basic genetics
  • Week 3: Genetic prognosis and genetic counselling
  • Week 4: Human population genetics
  • Week 5: Control test 3 (knowledge from week 13 of the autumn semester to week 4 of the spring semester - lectures, practices)
  • Week 6: Molecular diagnostics of cancer with respect to treatment options
  • Week 7: Gene engineering – production of human proteins in bacterial cells
  • Week 8: Molecular analysis of disease predispositions in humans
  • Week 9: Molecular diagnostics of human pathogenic bacteria
  • Week 10: Restriction mapping of DNA
  • Week 11: Genetic toxicology
  • Week 12: substitution practices – substitutions for public holidays
  • Week 13: Control test 4 (knowledge from week 5 to week 12 of the spring semester - lectures, practices)
  • Week 14: Re-sit tests 3 and 4
  • Week 15: credit awarding
Literatura
    povinná literatura
  • Protocols for practices are provided in electronic form in the Information System of the Masaryk University in the Study Materials of the course aZLBI0222c
Výukové metody
laboratory practice, class discussion
Metody hodnocení
Practical classes are mandatory.
Requirements for course completion: full attendance in the practices (1 absence, excused or unexcused, is allowed); all protocols completed (also for missed lessons) and checked and signed by appropriate teachers; successfully passed 2 written control tests during the semester (20 questions each, 4 possibilities, 1 answer correct, student need to reach at least 12 points out of 20 in each test). In case you do not pass one of the control tests and its re-sit, you have to pass the final test (so-called Credit test) based on knowledge of the entire semester lectures and practices. The test comprises of 20 questions: 10 test questions (multiple answers can be correct, negative marking is obtained for incorrect answers) + 10 given terms for written explanation. At least 10 points out of 20 are needed to pass.
In case of student’s late arrival to the practice or poor activity at the practice, the student is required to write an essay in the length of 2 pages on a given topic. Same for the case of 2nd and any additional absence in practices (excused or unexcused). Find the instructions for essay writing in the Course-related instructions in the IS, bring the essay printed to the teacher who specified the topic and be ready to answer the teacher's questions regarding the topic.
In case of 3 absences, (or more than 3 absences all excused by the Office for Studies within 5 days from the beginning of the absence and introduced to the Information System), it is addressed individually and course-unit credit is awarded only after the proof of the student's knowledge of the entire semester topics (Credit test, see above).
In case of 4 or more unexcused absences, course-unit credit is not awarded.
Vyučovací jazyk
Angličtina
Navazující předměty
Informace učitele
https://is.muni.cz/auth/el/1411/jaro2018/aZLBI0222c/index.qwarp
What to bring to each practice: printed protocol for the respective practice, your own writing materials. Download the protocol for each practice from the Study materials in the IS, and study it in advance. Lab shoes, lab coats and disposable gloves are not required, but for the tasks with staning lab coats are recommended.
Substitution of practices: In exceptional cases (illness, appointment at the doctor’s or foreign policy, 1 or 2 times per semester as maximum) student can arrange a substitution with another group. To arrange a substitution, write an e-mail to the contact person of the course at least 24 hours before your planned substitution and specify the group (date and time) you would like to attend instead. Substitution is only possible on the same teaching week. When the capacity of th group you intended to substitute with is fully used, the substitution does not need to be aproved. Repeated substitution with other groups is not allowed.
Complete Biology instructions to be found at the following link: https://is.muni.cz/auth/el/1411/jaro2018/aZLBI0222c/op/Biology_practices_instructions.pdf
Další komentáře
Předmět je vyučován každoročně.
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Předmět je zařazen také v obdobích jaro 2016, jaro 2017, jaro 2018, jaro 2020, jaro 2021, jaro 2022, jaro 2023, jaro 2024, jaro 2025.