BVZF0521 Basis of Pharmacology I

Faculty of Medicine
Autumn 2010
Extent and Intensity
0/1/0. 1 credit(s). Type of Completion: z (credit).
Teacher(s)
prof. MUDr. Alexandra Šulcová, CSc. (lecturer)
doc. PharmDr. Jan Juřica, Ph.D. (lecturer)
MVDr. Dagmar Vršková, Ph.D. (lecturer)
MUDr. Mgr. Karel Šlais, Ph.D. (lecturer)
doc. PharmDr. Jana Rudá, Ph.D. (seminar tutor)
doc. PharmDr. Ondřej Zendulka, Ph.D. (seminar tutor)
Mgr. Barbora Říhová, Ph.D. (seminar tutor)
MUDr. Jana Nováková, Ph.D. (lecturer)
MUDr. Jana Pistovčáková, Ph.D. (lecturer)
Guaranteed by
prof. MUDr. Alexandra Šulcová, CSc.
Department of Pharmacology – Theoretical Departments – Faculty of Medicine
Contact Person: Renata Bláblová
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
From the course on pharmacology students are expected to obtain: a) from lectures and seminars: a clarification of integration in the field of biomedical subjects such as chemistry, physiology, molecular biology, pathology and pathological physiology enabling them to understand why, what mechanism by, and what conditions on, drugs and their combinations may elicit therapeutic, adverse, and toxic effects. They will acquire an orientation in drug classes according to their main therapeutic indications with an attention paid to common drug-drug interactions. Information on drug development process, rules of preclinical and clinical drug testing will also be given. b) from practicals: a training in practical skills in "pharmacological thinking" in cases of need to make a choice of drug, dosing regimen, route and techniques of administration, and an elimination of adverse interactions with drugs simultaneously given.
Syllabus
  • AUTUMN SEMESTER
  • 1.LECTURE: Introduction into pharmacology. Terminology. Drug classification. Drug dosage forms and application routes.
  • 3.LECTURE: Mechanisms of drug effects. Basic pharmacokinetics.
  • 4.LECTURE: Adverse drug effects. General management of poisoning. Drug dependence. Rational Pharmacotherapy.
  • 5.LECTURE: Pharmacology of parasympathetic autonomic nervous system.
  • 6.LECTURE: Allergy and therapy. Histamine and antihistamine drugs.
  • 7.LECTURE: Pharmacotherapy of neoplastic diseases. Imunomodulation, imunosupression.
  • SEMINARS:
  • 1.SEMINAR: Drug prescription. Survey of drug dosage forms. Pharmacopoea.
  • 2. Practical preparation of selected drug dosage forms.
  • 3. Pharmacokinetic processes and parameters. Therapeutic drug monitoring. The use of computer techniques in pharmacokinetics. Practical computations of basic pharmacokinetic parameters.
  • 4.SEMINAR: Pharmacology of autonomic nervous system. Receptors and their pharmacological influence.
  • 5.SEMINAR: Pharmacology of parasympathetic autonomic nervous system.
  • 6.SEMINAR: Antiasthmatic drugs. TEST on autonomic nervous system.
  • 7.SEMINAR: Vitamins B, C, A, D, E, K. Supplements.
  • Revision, credits. multiplechoice test
  • SPRING SEMESTER:
  • 1. Antibiotics and chemotherapeutic drugs. Toxicants in nutritional chains - antibiotics, pesticides, etc.
  • 2. Nutritional pharmacology. Natural fiber, aminoacids, fish oils, fatty acids. Toxicants and additives in food. Tanins, glutamate, food preservatives and dyes. Dietary factors affecting drug efficacy. Drug effects on nutrient status..
  • 3. Drugs of abuse. Influence of smoking, therapy and prevention.
  • 4. Basic of phytopharmacology. What is homeopathy.
  • 5. Medical plants and their use. Excursion to the Center of medical plants.
  • 6. Pathophysiology and therapy of peptic ulcers. Antiemetics.
  • 7. Pathophysiology and therapy of diabetes mellitus. Insulines. Peroral antidiabetic drugs.
  • 8. Glucocorticoids, mechanism of effect. Anabolic drugs.
Literature
  • MARTÍNKOVÁ, Jiřina. Farmakologie pro studenty zdravotnických oborů. 1. vyd. Praha: Grada, 2007, 379 s. ISBN 9788024713564. info
  • MACH, Ivan. Doplňky stravy na našem trhu. Vyd. 1. Praha: Svoboda Servis, 2006, 118 s. ISBN 8086320464. info
  • PERLÍK, František. Základy farmakologie : klinická a speciální farmakologie. 1. vyd. Praha: Karolinum, 2005, 190 s. ISBN 8024611392. URL info
  • LÜLLMANN, Heinz. Barevný atlas farmakologie. 2., přeprac. a dopl. vyd. Praha: Grada, 2001, 382 s. ISBN 807169973X. info
  • HYNIE, Sixtus. Farmakologie v kostce. 2., přeprac. vyd. V Praze: Triton, 2001, 520 s. ISBN 8072541811. info
  • HYNIE, Sixtus. Farmakologie pro bakalářské studium. 2. přeprac. vyd. Praha: Karolinum, 1996, 272 s. ISBN 8071841846. info
  • HYNIE, Sixtus. Farmakologie pro bakalářské studium. 2. přeprac. vyd. Praha: Karolinum, 1996, s. i-x. ISBN 8071841854. info
Assessment methods
During the studying the student has to prove active knowledge of pharmacology acquired to get the credit. The student has to pass the final written multiple-choice test.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course is taught annually.
The course is taught: every week.
The course is also listed under the following terms Autumn 2000, Autumn 2001, Autumn 2002, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009.
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