BZFA0321p Pharmacology - lecture

Faculty of Medicine
Autumn 2010
Extent and Intensity
2/0. 1 credit(s). Recommended Type of Completion: zk (examination). Other types of completion: -.
Teacher(s)
prof. MUDr. Alexandra Šulcová, CSc. (lecturer)
doc. PharmDr. Jan Juřica, Ph.D. (lecturer)
MUDr. Jana Pistovčáková, Ph.D. (lecturer)
MUDr. Jana Nováková, Ph.D. (lecturer)
doc. PharmDr. Ondřej Zendulka, Ph.D. (lecturer)
MVDr. Dagmar Vršková, Ph.D. (lecturer)
MUDr. Alena Máchalová, Ph.D. (seminar tutor)
Mgr. Barbora Říhová, Ph.D. (seminar tutor)
MUDr. Mgr. Karel Šlais, Ph.D. (lecturer)
Guaranteed by
prof. MUDr. Alexandra Šulcová, CSc.
Department of Pharmacology – Theoretical Departments – Faculty of Medicine
Contact Person: Renata Bláblová
Timetable
Mon 20. 9. to Fri 26. 11. Mon 8:00–10:30 B11/327
Prerequisites (in Czech)
BKBC011p Biochemistry-lec || BSBC011p Biochemistry and Hematology
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
At the end of the course student should be able to understand mechanisms of xenobiotic (including drugs) effects and under which conditions they and their combinations may elicit therapeutic, adverse, and toxic effects, and what is the relation to the dose given, administration route, status of the organism (differences in pediatrics and geriatrics). They will be familiar with the requirements of "Good Clinical Practice" for development of new drugs, and duties of physicians in cooperation with the pharmaceutical industry and principles of pharmacovigilance. They will be able to recognize selected drug classes and pharmacological profiles of representative drugs from groups of drugs selected in the curriculum.
Syllabus
  • LECTURES:
  • 1. Drug classification. Mechanisms of drug effects. Basic pharmacokinetics. Drug interactions.
  • 2. Analgesic drugs. Non-steroidal antiinflammatory drugs.
  • 3. Adverse drug effects. General management of poisoning. Rationale pharmacotherapy. Preclinical and clinical drug evaluation.
  • 4. Local and general anaestetics.
  • 5. Neurotropic drugs, psychotropic drugs. Drugs of abuse.
  • 6. Pharmacotherapy of hypertension, angina pectoris, hyperlipidemia, heart failure and heart arrhythmias. Diuretics.
  • 7. Pharmacology of allergy. Histamine and antihistamine drugs. Drugs used in asthma
  • 8. Pathophysiology and therapy of diabetes mellitus. Insulines. Peroral antidiabetic drugs. Glucocorticoids, mechanism of effect.
  • 9. Pharmacotherapy of neoplastic diseases. Immunomostimulation, immunosupression.
  • 10. Antibiotics and chemoterapeutics, antiviral agents, antimycotic agents, antiprotozoic agents.
Literature
  • Martínková, Jiřina. Farmakologie. Pro studenty zdravotnických oborů, Grada Publishing, 2007. 380 s. ISBN 978-80-247-1356-4
  • František, Perlík. Základy farmakologie.Klinická a speciální farmakologie. 1. vyd. Praha: Galén a Univerzita Karlova v Praze (Karolinum), 2005. 190 s. ISBN 80-7262-374-5 (Galén), ISBN 80-246-1139-2 (Karolinum).
  • MACH, Ivan. Doplňky stravy na našem trhu. Vyd. 1. Praha: Svoboda Servis, 2006, 118 s. ISBN 8086320464. info
  • LÜLLMANN, Heinz. Barevný atlas farmakologie. 2., přeprac. a dopl. vyd. Praha: Grada, 2001, 382 s. ISBN 807169973X. info
  • HYNIE, Sixtus. Farmakologie v kostce. 2., přeprac. vyd. V Praze: Triton, 2001, 520 s. ISBN 8072541811. info
  • HYNIE, Sixtus. Farmakologie pro bakalářské studium. 2. přeprac. vyd. Praha: Karolinum, 1996, 272 s. ISBN 8071841846. info
  • HYNIE, Sixtus. Farmakologie pro bakalářské studium. 2. přeprac. vyd. Praha: Karolinum, 1996, s. i-x. ISBN 8071841854. info
  • Výběr z učebnice pro střední zdravotnické školy, Neuwirth, Jiří. Klinická propedeutika. Praha : Avicenum, 1989 - k zapůjčení na Farmakologickém ústavu.
  • Vybrané kapitoly z učebnice: http://books.google.cz/books?id=7lNQpLuETq4C&printsec=frontcover&dq=farmakologie&lr=&as_brr=3#PPA4,M1
  • Vybrané kapitoly z učebnice: http://books.google.cz/books?ct=result&q=farmakologie&lr=&as_brr=3&sa=N&start=0
Teaching methods
The curriculum enables attendance at lectures read by teachers of pharmacology.
Assessment methods
During the studying the students have to prove active knowledge of pharmacology acquired. Students have to pass the exam: final written multiple-choice test. In the Final Exam students are asked to answer to multiple-choice questions. Only 1 correct answer is possible to each question. The test contains 30 questions generated randomly for each single student. One point is granted for each correctly answered question. 0.5 point will be distracted for an incorrect answer to the multiple-choice question. The summary of the score obtained is evaluated as follows: mark A = 91-100% out of the maximum score; B = 81-90%; C = 71-80%; D = 61-70%; E = 51-60%; F = failed with the score below 50% of the maximum score.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course is taught annually.
The course is also listed under the following terms Autumn 2000, Autumn 2001, Autumn 2002, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009.
  • Enrolment Statistics (recent)
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