BDBC011 Biochemistry and hematology

Faculty of Medicine
autumn 2019
Extent and Intensity
1/0/0. 3 credit(s). Type of Completion: zk (examination).
Teacher(s)
doc. RNDr. Jiří Dostál, CSc. (lecturer)
RNDr. Hana Paulová, CSc. (lecturer)
Mgr. Jiří Slanina, Ph.D. (lecturer)
prof. RNDr. Eva Táborská, CSc. (lecturer)
doc. RNDr. Josef Tomandl, Ph.D. (lecturer)
Mgr. Jana Gregorová, Ph.D. (assistant)
MUDr. Miroslava Hlaváčová, Ph.D. (assistant)
MUDr. Michaela Králíková, Ph.D. (assistant)
Lenka Nerudová (assistant)
doc. Mgr. Ondřej Peš, Ph.D. (assistant)
Mgr. Marie Tomandlová, Ph.D. (assistant)
Guaranteed by
prof. RNDr. Eva Táborská, CSc.
Department of Biochemistry – Theoretical Departments – Faculty of Medicine
Supplier department: Department of Biochemistry – Theoretical Departments – Faculty of Medicine
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The course aim is to get the basic knowledge of biochemical processes in the human body.
Learning outcomes
After the completition of the subject student will understand physico-chemical processes important for biological systems, He is able to explain basic principles of nutrient metabolism, discusses the principles of regulation. Understands how energy is generated, used, and stored by the various organs of the body.Describes the biochemical proceses typical for main organs and tissues in the body (heart, liver, kidney muscle, nerve tissue). He is able to explain basic principles of homeostasis. He is familiar with the effects of major hormones and the principle of their action through receptors. Characterizes the composition and function of the main body fluids. Understands the processes of hemocoagulation.
Syllabus
  • Biochemistry for bacherols follows secondary school chemistry and broadens the subject considerably to the level required for the study of successive subjects. There are covered the basic principles of chemistry as well as the survey of biochemically important inorganic and organic compounds. A special attention is paid to the structures and chemistry of saccharides, lipids, steroids, amino acids, proteins, nucleotides, and nucleic acids. Biochemical part deals with the metabolism of nutrients including biochemistry of muscles and vision.
  • Atomic structure. Chemical bonds.
  • Latin nomenclature.
  • Chemical reactions. Basic chemical calculations.
  • Solutions. Acids and bases. Osmotic pressure.
  • Redox reactions. Adsorbents, detergents.
  • Biochemically important elements and their compounds.
  • Organic compounds. Hydrocarbons. Alcohols, phenols, ethers.
  • Carbonyl compounds. Carboxylic acids and their deivatives.
  • Nitrocompounds, amines, heterocycles and their biochemically important derivatives.
  • The chemistry of saccharides.
  • Aminoacids, peptides, proteins. Biocatalysis. Types of enzymes, enzyme nomenclature.
  • Lipids, phospholipids, glycolipids. Eicosanoids, steroids.
  • Nucleosides and nucleotides, types of nucleic acids.
  • Hemoproteins. Heme. Bile pigments.
  • General principles of metabolism. High-energy compounds. Citric acid cycle. Respiration chain, aerobic phosphorylation.
  • Saccharide metabolism, glycolysis, gluconeogenesis, synthesis of glycogen.
  • Metabolism of proteins and amino acids. Proteins in food and their digestion. Synthesis of urea.
  • Digestion and resorption of lipids. Fatty acid metabolism, ketogenesis. Cholesterol.
  • Hormones, mechanism of their action. Neurone, neurotransmitters.
  • Muscle proteins, molecular principles of contraction and relaxation.
  • Metabolism of xenobiotics.
  • Biochemistry of vision, rhodopsine cycle. Metabolism of the cornea and the lens.
Literature
Teaching methods
Teaching form is lecture.
Assessment methods
Oral examination has three questions.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course is taught annually.
The course is taught: every week.
Information on the extent and intensity of the course: 15.
The course is also listed under the following terms Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, Autumn 2017, autumn 2018.
  • Enrolment Statistics (recent)
  • Permalink: https://is.muni.cz/course/med/autumn2019/BDBC011