aBFBI011 Biology - lecture

Faculty of Medicine
autumn 2019
Extent and Intensity
2/0/0. 3 credit(s). Type of Completion: zk (examination).
Teacher(s)
Ing. Lívia Eiselleová, Ph.D. (lecturer)
Mgr. Kateřina Vopěnková, Ph.D. (lecturer)
prof. MUDr. Iva Slaninová, Ph.D. (lecturer)
Mgr. Kateřina Straková, Ph.D. (lecturer)
Mgr. Michaela Bosáková, Ph.D. (lecturer)
prof. RNDr. Ondřej Slabý, Ph.D. (lecturer)
Jana Růžičková (assistant)
Mgr. Kateřina Cetkovská, Ph.D. (alternate examiner)
Guaranteed by
prof. MUDr. Iva Slaninová, Ph.D.
Department of Biology – Theoretical Departments – Faculty of Medicine
Contact Person: Ing. Lívia Eiselleová, Ph.D.
Supplier department: Department of Biology – Theoretical Departments – Faculty of Medicine
Timetable
Fri 12:00–13:50 B11/334
Prerequisites
Knowledge high-school biology at the level of Overview of High School Biology (https://is.muni.cz/auth/do/med/el/overview/overview_CZ.qwarp) or similar.
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The main objectives of the course are:
- understanding the chemical composition, structure and properties of the main cellular components
- understanding the basic processes in the cell; and understanding the principles of pathology of these processes in cancer and genetic diseases
- understanding the basic principles of heredity
Learning outcomes
After completing the course, the student will be able to:
- describe the composition, structure and functions of prokaryotic and eukaryotic cells
- Explain the principles of intercellular communication and cell differentiation
- Explain the principles of regulation and purpose of cell division (mitosis and meiosis)
- explain basic principles of heredity and nature of human genetic diseases, describe basic methods of gene diagnostics
- Explain the principles of tumour transformation
Syllabus
  • Week 1: Introduction. Biopolymers I – proteins
  • Week 2: Biopolymers II – nucleic acids and DNA replication
  • Week 3: From a gene to protein – the expression of genetic information
  • Week 4: Cell architecture and functions of eukaryotic cells
  • Week 5: Cytoskeletal system in cells
  • Week 6: Cell communication, cell differentiation. Stem cells
  • Week 7: Mitosis and meiosis
  • Week 8: Cell division and cell cycle control, apoptosis
  • Week 9: Principles of heredity I – genes and gene mutations
  • Week 10: Principles of heredity II – the karyotype and chromosomal aberrations
  • Week 11: Methods of genome studying. Gene diagnostics
  • Week 12: Bacteria and viruses
  • Week 13: Malignant transformation of cells, cancer
  • Week 14: substitution lecture
Literature
    recommended literature
  • ALBERTS, Bruce. Essential cell biology. 4th edition. New York, N.Y.: Garland Science, 2014, xxiii, 726. ISBN 9780815344551. info
  • Medical genetics at a glance. Edited by D. J. Pritchard - Bruce R. Korf. 3rd ed. Chichester, England: Wiley-Blackwell, 2013, 1 online r. ISBN 9781118689028. info
Teaching methods
two-hour lecture with discussion per week
Assessment methods
The course is completed with a written examination test with 60 questions (30 multiple choice questions, where negative marking applies for incorrect answers + 30 questions where the student chooses from true/false). At least 30 points out of 60 are needed to pass. More information on the exam to be found on https://is.muni.cz/auth/el/1411/podzim2019/aBFBI011/op/Exam_information_and_instructions.pdf
The exam tests the understanding of the discussed knowledge.
Language of instruction
English
Follow-Up Courses
Further comments (probably available only in Czech)
The course is taught annually.
Information on the extent and intensity of the course: 30.
Teacher's information
https://is.muni.cz/auth/el/1411/podzim2019/aBFBI011/index.qwarp
You can find all important information about the course organisation, study materials, etc., in the Interactive syllabus of the course: https://is.muni.cz/auth/el/1411/podzim2019/aBFBI011/index.qwarp.

When you lack understanding of some topic from the lectures, study the respective topic in the recommended textbooks at the extent of the syllabus, or come to discuss the problem in the consulting hours.

The course is also listed under the following terms Autumn 2015, Autumn 2016, Autumn 2017, autumn 2018, autumn 2020, autumn 2021.
  • Enrolment Statistics (autumn 2019, recent)
  • Permalink: https://is.muni.cz/course/med/autumn2019/aBFBI011