aBFBI011 Biology - lecture

Faculty of Medicine
autumn 2020
Extent and Intensity
2/0/0. 3 credit(s). Type of Completion: zk (examination).
Teacher(s)
Mgr. Kateřina Straková, Ph.D. (lecturer)
Ing. Lívia Eiselleová, Ph.D. (lecturer)
prof. MUDr. Iva Slaninová, Ph.D. (lecturer)
Mgr. Kateřina Cetkovská, Ph.D. (lecturer)
Mgr. Kateřina Francová, Ph.D. (lecturer)
prof. RNDr. Ondřej Slabý, Ph.D. (lecturer)
Jana Růžičková (assistant)
Guaranteed by
prof. MUDr. Iva Slaninová, Ph.D.
Department of Biology – Theoretical Departments – Faculty of Medicine
Contact Person: Mgr. Kateřina Straková, Ph.D.
Supplier department: Department of Biology – Theoretical Departments – Faculty of Medicine
Timetable
Fri 13:00–14:50 B11/211
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The main objectives of the course are:
- understanding the chemical composition, structure and properties of the main cellular components
- understanding the basic processes in the cell; and understanding the principles of pathology of these processes in cancer and genetic diseases
- understanding the basic principles of heredity
Learning outcomes
After completing the course the student will be able to:
- describe the composition, structure and functions of prokaryotic and eukaryotic cells
- Explain the principles of intercellular communication and cell differentiation
- Explain the principles of regulation and purpose of cell division (mitosis and meiosis)
- explain basic principles of heredity and nature of human genetic diseases, describe basic methods of gene diagnostics
- Explain the principles of tumour transformation
Syllabus
  • Week 1: Introduction. Basic properties of living organisms. Proteins and their functions
  • Week 2: Bacteria and viruses. Human microbiome
  • Week 3: Architecture and functions of eukaryotic cells, biomembranes
  • Week 4: Nucleic acids. Structure of chromosomes. DNA replication
  • Week 5: From genes to proteins – expression of genetic information. Transcription and translation
  • Week 6: Cell signalling. Cell differentiation. Stem cells
  • Week 7: Cytoskeletal system of cells and principles of cell organization in tissues
  • Week 8: Cell cycle and mitosis, regulation of cell division
  • Week 9: DNA damage and repair, cell death
  • Week 10: Meiosis and gametogenesis. Genetics I - karyotype, chromosomal aberrations
  • Week 11: Genetics II - principle of dominance and recessivity, Mendelian and non-Mendelian inheritance
  • Week 12: Methods of gene studying. Gene diagnostics, gene therapy
  • Week 13: Malignant transformation of cells. Cancer
  • Week 14: substitution lecture
Literature
    recommended literature
  • ALBERTS, Bruce. Essential cell biology. 4th edition. New York, N.Y.: Garland Science, 2014, xxiii, 726. ISBN 9780815344551. info
  • Medical genetics at a glance. Edited by D. J. Pritchard - Bruce R. Korf. 3rd ed. Chichester, England: Wiley-Blackwell, 2013, 1 online r. ISBN 9781118689028. info
Teaching methods
lecture and class discussion
Assessment methods
The course is completed with a written examination test. The test comprises of 30 questions: 15 test questions (multiple answers can be correct, negative marking is obtained for incorrect answers) + 15 given terms for a written explanation. At least 15 points out of 30 are needed to pass. The exam tests the understanding of the discussed knowledge.
The exam requires knowledge of high-school biology at the level of Overview of High School Biology (https://is.muni.cz/auth/do/med/el/overview/overview_ENG.qwarp) or similar, and the knowledge discussed at the lectures.
Language of instruction
English
Follow-Up Courses
Further comments (probably available only in Czech)
The course is taught annually.
Information on the extent and intensity of the course: 30.
Teacher's information
https://is.muni.cz/auth/el/1411/podzim2017/aBFBI011/index.qwarp
The course is also listed under the following terms Autumn 2015, Autumn 2016, Autumn 2017, autumn 2018, autumn 2019, autumn 2021.
  • Enrolment Statistics (autumn 2020, recent)
  • Permalink: https://is.muni.cz/course/med/autumn2020/aBFBI011