BVBV0321s Nutritional Biochemistry I - seminary

Faculty of Medicine
autumn 2021
Extent and Intensity
0/3/0. 3 credit(s). Type of Completion: zk (examination).
Teacher(s)
Mgr. Marie Tomandlová, Ph.D. (seminar tutor)
doc. RNDr. Jiří Dostál, CSc. (seminar tutor)
RNDr. Hana Paulová, CSc. (assistant)
Mgr. Jiří Slanina, Ph.D. (assistant)
prof. RNDr. Eva Táborská, CSc. (assistant)
doc. RNDr. Josef Tomandl, Ph.D. (assistant)
Bc. Ivana Ševčíková (assistant)
Guaranteed by
Mgr. Marie Tomandlová, Ph.D.
Department of Biochemistry – Theoretical Departments – Faculty of Medicine
Supplier department: Department of Biochemistry – Theoretical Departments – Faculty of Medicine
Timetable
Thu 16. 9. 13:00–15:30 A16/213, Thu 23. 9. 13:00–15:30 A16/213, Thu 30. 9. 13:00–15:30 A16/213, Thu 7. 10. 13:00–15:30 A16/213, Thu 14. 10. 13:00–15:30 A16/213, Thu 21. 10. 13:00–15:30 A16/213, Thu 4. 11. 13:00–15:30 A16/213, Thu 11. 11. 13:00–15:30 A16/213, Thu 18. 11. 13:00–15:30 A16/213, Thu 25. 11. 13:00–15:30 A16/213, Thu 2. 12. 13:00–15:30 A16/213, Thu 9. 12. 13:00–15:30 A16/213, Thu 16. 12. 13:00–15:30 A16/213
Prerequisites (in Czech)
BVLC011p Med.Chem.- lecture && BVBC0221p Biochemistry - lect.
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The aim of the course is to introduce dietitian to the solution of nutrition problems from biochemical point of view, with the influence of composition and amount of diet on a healthy person, changes in metabolism of some diseases / disorders and main nutritional needs in disease prevention and care of the patient.
Learning outcomes
Student is able to explain the interrelationship between the metabolism of nutrients under different states of the organism. Describes the metabolic characteristics of major organs and tissues and major disorders, discusses their association with diseases. Understands and discusses principles of maintaining homeostasis and acid-base balance in the organism, including modeling situations It discusses the composition of body fluids and their disorders in connection with the principles of homeostasis. It explains the principles of metabolism regulation at all levels.
Syllabus
  • • Laboratory tests in clinical biochemistry. Sources of error, assessing the significance of a test result. Enzyme assays in clinical diagnostics.
  • • Conversions and absorption of food components in gastrointestinal tract. Biochemical processes in the mouth, stomach, small and large intestine. Essential enzymes and hormones acting in GIT. Metabolism of enterocyte. Biochemistry of pankreas.
  • • Glucose in blood (origin, consumption, regulation). Diabetes mellitus. Disturbances of fructose and galactose metabolism. Investigations of glucose metabolism.
  • • Proteins in nutrition. Assessment of quality. Absorption of amino acids, utilization of amino acids in tissues, blood transport of ammonia, glutamine and its role in metabolism. Excretion of nitrogen compounds by urine. Nitrogen balance.
  • • Plasma lipoproteins, interconversion of lipoproteins. Cholesterol transport, balance of cholesterol intake and excretion. Ways affecting the plasmatic level of cholesterol.
  • • Integration of metabolism of nutrients: relationships among the major metabolic pathways in the fed state, postabsorptive state, prolonged starvation. Metabolism in stress conditions, muscle work. Obesity. Malnutrition.
  • • Principles of xenobiotics biotransformation. Metabolism of ethanol.
  • • The liver functions – the role in metabolism of nutrients, hormones, and vitamins. Catabolism of hemoglobin, urobilinoids, the types of hyperbilirubinemia. Biochemical investigations of liver function.
  • • Principles of neurotransmitter and hormone effects. Types and structures of receptors.
  • • Regulation of metabolism. Metabolism of nervous tissue. Processes on synapses.
  • • The major proteins of blood plasma, function.
  • • Metabolism of iron and copper.
  • • Biochemistry of blood cells. The blood-coagulation cascade, inhibition of clotting. Significance of folate and B12, vitamins K.
Literature
    recommended literature
  • LEDVINA, Miroslav, Alena STOKLASOVÁ and Jaroslav CERMAN. Biochemie pro studující medicíny, I. a II. díl. Druhé vydání. Praha: Karolinum, 2009, 546 pp. ISBN 978-80-246-1414-4. info
  • KOOLMAN, Jan and Klaus-Heinrich RÖHM. Barevný atlas biochemie. 1st ed. Praha: Grada, 2012, 498 pp. ISBN 978-80-247-2977-0. info
  • Podklady pro semináře v IS.
Teaching methods
Course has a form seminars and discussions on given issues and topics in seminars.
Assessment methods
Oral examination.
Language of instruction
Czech
Further comments (probably available only in Czech)
Information on the extent and intensity of the course: 45.
Listed among pre-requisites of other courses
The course is also listed under the following terms Autumn 2014, Autumn 2015, Autumn 2016, Autumn 2017, autumn 2018, autumn 2019, autumn 2020, autumn 2022, autumn 2023, autumn 2024.
  • Enrolment Statistics (autumn 2021, recent)
  • Permalink: https://is.muni.cz/course/med/autumn2021/BVBV0321s