BHBB011s Cell biology and genetics - seminar

Faculty of Medicine
autumn 2023
Extent and Intensity
0/2/0. 2 credit(s). Type of Completion: k (colloquium).
Teacher(s)
Mgr. Kateřina Cetkovská, Ph.D. (lecturer)
Ing. Lívia Eiselleová, Ph.D. (lecturer)
Mgr. Kateřina Francová, Ph.D. (lecturer)
prof. RNDr. Ondřej Slabý, Ph.D. (lecturer)
prof. MUDr. Iva Slaninová, Ph.D. (lecturer)
Mgr. Kateřina Straková, Ph.D. (lecturer)
Jana Růžičková (assistant)
Guaranteed by
prof. MUDr. Iva Slaninová, Ph.D.
Department of Biology – Theoretical Departments – Faculty of Medicine
Contact Person: Ing. Lívia Eiselleová, Ph.D.
Supplier department: Department of Biology – Theoretical Departments – Faculty of Medicine
Timetable
Tue 10:00–11:40 C15/333
Prerequisites
Knowledge high-school biology on the level of Overview of High School Biology (https://is.muni.cz/auth/do/med/el/overview/overview_CZ.qwarp) or similar.
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.

The capacity limit for the course is 30 student(s).
Current registration and enrolment status: enrolled: 23/30, only registered: 1/30
fields of study / plans the course is directly associated with
Course objectives
The main objectives of the course are:
- understanding the chemical composition, structure and properties of the main cellular components
- understanding the basic processes in the cell; and understanding the principles of pathology of these processes in cancer and genetic diseases
- understanding the basic principles of heredity
Learning outcomes
After completing the course the student will be able to:
- describe the composition, structure and functions of prokaryotic and eukaryotic cells
- Explain the principles of regulation and purpose of cell division (mitosis and meiosis)
- explain basic principles of heredity and nature of human genetic diseases
- describe basci strategies of tissue engineering in current medicine
- Explain the principles of tumour transformation
Syllabus
  • Week 1: Introduction. Basic properties of living organisms. Proteins and their functions
  • Week 2: Bacteria and viruses. Human microbiome
  • Week 3: Architecture and function of eukaryotic cell
  • Week 4: Nucleic acids. Structure of chromosomes. DNA replication
  • Week 5: DNA damage and repair, cell death
  • Week 6: From genes to proteins – expression of genetic information
  • Week 7: Cell signalling. Cell differentiation. Stem cells
  • Week 8: Cytoskeletal system of cells and principles of cell organization in tissues
  • Week 9: Cell cycle and mitosis, regulation of cell division
  • Week 10: Meiosis and gametogenesis. Karyotype, chromosomal aberrations
  • Week 11: Genes and gene mutations - Mendelian and non-Mendelian inheritance
  • Week 12: Malignant transformation of cells. Cancer
  • Week 13: Methods of gene studying. Gene diagnostics, gene therapy
  • Week 14: colloquium
Literature
    required literature
  • Aktuální prezentace k seminářům jsou dostupné pouze v elektronické podobě na stránkách informačního systému MU (ISu): Studijní materiály předmětu BHBB011s
    recommended literature
  • SLABÝ, Ondřej. Lékařská biologie. 1. vydání. Brno: Masarykova univerzita, 2022, 268 stran. ISBN 9788028000608. info
  • SLABÝ, Ondřej. Lékařská biologie II. Genetika a molekulární medicína (Medical Biology II. Genetics and molecular medicine). 1st ed. Brno: Masarykova univerzita, 2023, 227 pp. ISBN 978-80-280-0338-8. info
  • ALBERTS, Bruce. Základy buněčné biologie : úvod do molekulární biologie buňky. Translated by Arnošt Kotyk. 2. vyd. Ústí nad Labem: Espero Publishing, 2004, xxvi, 630. ISBN 8090290620. info
  • PRITCHARD, D. J. and Bruce R. KORF. Základy lékařské genetiky. první české vydání. Praha: Galén, 2007, 182 stran. ISBN 9788072624492. info
Teaching methods
2-hour seminar per week
Assessment methods
Attendance at all seminars is mandatory. An absence must be excused at the Office for Studies within five days from the beginning of the absence. In case of unexcused absence, credit is not awarded.
The course is finished by a colloquium - discussion with the teacher, who decides whether the student's knowledge is sufficient. See the topics for the colloquium in Interactive syllabus of the course.
Language of instruction
Czech
Follow-Up Courses
Further comments (probably available only in Czech)
Study Materials
Information on completion of the course: Základní podmínkou je absolvování všech seminářů, absence musí být omluveny cestou studijního oddělení do 5 dnů od začátku absence. Bude ukončen kolokviem – rozhovorem s vyučujícím, který ověří znalosti studentů.
The course is taught annually.
Information on the extent and intensity of the course: 30.
Listed among pre-requisites of other courses
Teacher's information
https://is.muni.cz/auth/el/med/podzim2023/BHBB011s/index.qwarp
Follow the Interactive syllabus of the course: https://is.muni.cz/auth/el/med/podzim2023/BHBB011s/index.qwarp
The course is also listed under the following terms Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2017, autumn 2018, autumn 2019, autumn 2020, autumn 2021, autumn 2022, autumn 2024.
  • Enrolment Statistics (autumn 2023, recent)
  • Permalink: https://is.muni.cz/course/med/autumn2023/BHBB011s