aVLBI0121c Lékařská Biologie I - cvičení

Lékařská fakulta
podzim 2023
Rozsah
0/3/0. 45. 3 kr. Ukončení: z.
Vyučující
prof. RNDr. Ondřej Slabý, Ph.D. (přednášející)
Ing. Lívia Eiselleová, Ph.D. (cvičící)
Mgr. Kateřina Cetkovská, Ph.D. (cvičící)
Mgr. Andrej Bešše, Dr. sc. nat. (cvičící)
Mgr. Lenka Bešše, Ph.D. (cvičící)
Pooja Dudeja (cvičící)
Mgr. Kateřina Francová, Ph.D. (cvičící)
Monica Medappa, Ph.D. (cvičící)
Mgr. Petra Pospíšilová, Ph.D. (cvičící)
Ing. Mgr. Michaela Ručková (cvičící)
prof. MUDr. Iva Slaninová, Ph.D. (cvičící)
Mgr. Bc. Karolína Smolková (cvičící)
Mgr. Kateřina Straková, Ph.D. (cvičící)
Vlad-Constantin Ursachi (cvičící)
Ing. Natália Vadovičová (cvičící)
Jana Růžičková (pomocník)
Garance
prof. RNDr. Ondřej Slabý, Ph.D.
Biologický ústav – Teoretická pracoviště – Lékařská fakulta
Kontaktní osoba: Ing. Lívia Eiselleová, Ph.D.
Dodavatelské pracoviště: Biologický ústav – Teoretická pracoviště – Lékařská fakulta
Rozvrh seminárních/paralelních skupin
aVLBI0121c/30: Út 19. 9. 13:00–14:00 B07/214, 14:00–15:00 B07/214, 14:00–15:00 B07/217, 15:00–15:30 B07/214, Út 26. 9. 13:00–14:00 B07/214, 14:00–15:00 B07/217, 14:00–15:00 B07/214, 15:00–15:30 B07/214, Út 3. 10. 13:00–14:00 B07/214, 14:00–15:00 B07/217, 14:00–15:00 B07/214, 15:00–15:30 B07/214, Út 10. 10. 13:00–14:00 B07/214, 14:00–15:00 B07/217, 14:00–15:00 B07/214, 15:00–15:30 B07/214, Út 17. 10. 13:00–14:00 B07/214, 14:00–15:00 B07/214, 14:00–15:00 B07/217, 15:00–15:30 B07/214, Út 24. 10. 13:00–14:00 B07/214, 14:00–15:00 B07/214, 14:00–15:00 B07/217, 15:00–15:30 B07/214, Út 31. 10. 13:00–14:00 B07/214, 14:00–15:00 B07/214, 14:00–15:00 B07/217, ...
aVLBI0121c/31: Út 19. 9. 16:00–17:00 B07/214, 17:00–18:00 B07/217, 17:00–18:00 B07/214, 18:00–18:30 B07/214, Út 26. 9. 16:00–17:00 B07/214, 17:00–18:00 B07/217, 17:00–18:00 B07/214, 18:00–18:30 B07/214, Út 3. 10. 16:00–17:00 B07/214, 17:00–18:00 B07/217, 17:00–18:00 B07/214, 18:00–18:30 B07/214, Út 10. 10. 16:00–17:00 B07/214, 17:00–18:00 B07/217, 17:00–18:00 B07/214, 18:00–18:30 B07/214, Út 17. 10. 16:00–17:00 B07/214, 17:00–18:00 B07/214, 17:00–18:00 B07/217, 18:00–18:30 B07/214, Út 24. 10. 16:00–17:00 B07/214, 17:00–18:00 B07/214, 17:00–18:00 B07/217, 18:00–18:30 B07/214, Út 31. 10. 16:00–17:00 B07/214, 17:00–18:00 B07/217, 17:00–18:00 B07/214, ...
aVLBI0121c/32: Pá 22. 9. 13:00–14:00 B07/214, 14:00–15:00 B07/217, 14:00–15:00 B07/214, 15:00–15:30 B07/214, Pá 29. 9. 13:00–14:00 B07/214, 14:00–15:00 B07/214, 14:00–15:00 B07/217, 15:00–15:30 B07/214, Pá 6. 10. 13:00–14:00 B07/214, 14:00–15:00 B07/217, 14:00–15:00 B07/214, 15:00–15:30 B07/214, Pá 13. 10. 13:00–14:00 B07/214, 14:00–15:00 B07/217, 14:00–15:00 B07/214, 15:00–15:30 B07/214, Pá 20. 10. 13:00–14:00 B07/214, 14:00–15:00 B07/214, 14:00–15:00 B07/217, 15:00–15:30 B07/214, Pá 27. 10. 13:00–14:00 B07/214, 14:00–15:00 B07/217, 14:00–15:00 B07/214, 15:00–15:30 B07/214, Pá 3. 11. 13:00–14:00 B07/214, 14:00–15:00 B07/217, 14:00–15:00 B07/214, ...
aVLBI0121c/33: St 20. 9. 15:00–16:00 B07/214, 16:00–17:00 B07/214, 16:00–17:00 B07/217, 17:00–17:30 B07/214, St 27. 9. 15:00–16:00 B07/214, 16:00–17:00 B07/217, 16:00–17:00 B07/214, 17:00–17:30 B07/214, St 4. 10. 15:00–16:00 B07/214, 16:00–17:00 B07/217, 16:00–17:00 B07/214, 17:00–17:30 B07/214, St 11. 10. 15:00–16:00 B07/214, 16:00–17:00 B07/214, 16:00–17:00 B07/217, 17:00–17:30 B07/214, St 18. 10. 15:00–16:00 B07/214, 16:00–17:00 B07/217, 16:00–17:00 B07/214, 17:00–17:30 B07/214, St 25. 10. 15:00–16:00 B07/214, 16:00–17:00 B07/214, 16:00–17:00 B07/217, 17:00–17:30 B07/214, St 1. 11. 15:00–16:00 B07/214, 16:00–17:00 B07/214, 16:00–17:00 B07/217, ...
aVLBI0121c/34: Čt 21. 9. 15:00–16:00 B07/214, 16:00–17:00 B07/214, 16:00–17:00 B07/217, 17:00–17:30 B07/214, Čt 5. 10. 15:00–16:00 B07/214, 16:00–17:00 B07/217, 16:00–17:00 B07/214, 17:00–17:30 B07/214, Čt 12. 10. 15:00–16:00 B07/214, 16:00–17:00 B07/214, 16:00–17:00 B07/217, 17:00–17:30 B07/214, Čt 19. 10. 15:00–16:00 B07/214, 16:00–17:00 B07/217, 16:00–17:00 B07/214, 17:00–17:30 B07/214, Čt 26. 10. 15:00–16:00 B07/214, 16:00–17:00 B07/214, 16:00–17:00 B07/217, 17:00–17:30 B07/214, Čt 2. 11. 15:00–16:00 B07/214, 16:00–17:00 B07/217, 16:00–17:00 B07/214, 17:00–17:30 B07/214, Čt 9. 11. 15:00–16:00 B07/214, 16:00–17:00 B07/214, 16:00–17:00 B07/217, ...
aVLBI0121c/35: Po 18. 9. 16:00–17:00 B07/214, 17:00–18:00 B07/214, 17:00–18:00 B07/217, 18:00–18:30 B07/214, Po 25. 9. 16:00–17:00 B07/214, 17:00–18:00 B07/214, 17:00–18:00 B07/217, 18:00–18:30 B07/214, Po 2. 10. 16:00–17:00 B07/214, 17:00–18:00 B07/214, 17:00–18:00 B07/217, 18:00–18:30 B07/214, Po 9. 10. 16:00–17:00 B07/214, 17:00–18:00 B07/217, 17:00–18:00 B07/214, 18:00–18:30 B07/214, Po 16. 10. 16:00–17:00 B07/214, 17:00–18:00 B07/214, 17:00–18:00 B07/217, 18:00–18:30 B07/214, Po 23. 10. 16:00–17:00 B07/214, 17:00–18:00 B07/217, 17:00–18:00 B07/214, 18:00–18:30 B07/214, Po 30. 10. 16:00–17:00 B07/214, 17:00–18:00 B07/214, 17:00–18:00 B07/217, ...
aVLBI0121c/36: Po 18. 9. 8:00–9:00 B07/214, 9:00–10:00 B07/214, 9:00–10:00 B07/217, 10:00–10:30 B07/214, Po 25. 9. 8:00–9:00 B07/214, 9:00–10:00 B07/214, 9:00–10:00 B07/217, 10:00–10:30 B07/214, Po 2. 10. 8:00–9:00 B07/214, 9:00–10:00 B07/214, 9:00–10:00 B07/217, 10:00–10:30 B07/214, Po 9. 10. 8:00–9:00 B07/214, 9:00–10:00 B07/214, 9:00–10:00 B07/217, 10:00–10:30 B07/214, Po 16. 10. 8:00–9:00 B07/214, 9:00–10:00 B07/217, 9:00–10:00 B07/214, 10:00–10:30 B07/214, Po 23. 10. 8:00–9:00 B07/214, 9:00–10:00 B07/214, 9:00–10:00 B07/217, 10:00–10:30 B07/214, Po 30. 10. 8:00–9:00 B07/214, 9:00–10:00 B07/217, 9:00–10:00 B07/214, ...
aVLBI0121c/37: Út 19. 9. 9:00–10:00 B07/214, 10:00–11:00 B07/214, 10:00–11:00 B07/217, 11:00–11:30 B07/214, Út 26. 9. 9:00–10:00 B07/214, 10:00–11:00 B07/217, 10:00–11:00 B07/214, 11:00–11:30 B07/214, Út 3. 10. 9:00–10:00 B07/214, 10:00–11:00 B07/217, 10:00–11:00 B07/214, 11:00–11:30 B07/214, Út 10. 10. 9:00–10:00 B07/214, 10:00–11:00 B07/214, 10:00–11:00 B07/217, 11:00–11:30 B07/214, Út 17. 10. 9:00–10:00 B07/214, 10:00–11:00 B07/214, 10:00–11:00 B07/217, 11:00–11:30 B07/214, Út 24. 10. 9:00–10:00 B07/214, 10:00–11:00 B07/217, 10:00–11:00 B07/214, 11:00–11:30 B07/214, Út 31. 10. 9:00–10:00 B07/214, 10:00–11:00 B07/217, 10:00–11:00 B07/214, ...
aVLBI0121c/38: Pá 22. 9. 10:00–11:00 B07/214, 11:00–12:00 B07/214, 11:00–12:00 B07/217, 12:00–12:30 B07/214, Pá 29. 9. 10:00–11:00 B07/214, 11:00–12:00 B07/214, 11:00–12:00 B07/217, 12:00–12:30 B07/214, Pá 6. 10. 10:00–11:00 B07/214, 11:00–12:00 B07/214, 11:00–12:00 B07/217, 12:00–12:30 B07/214, Pá 13. 10. 10:00–11:00 B07/214, 11:00–12:00 B07/217, 11:00–12:00 B07/214, 12:00–12:30 B07/214, Pá 20. 10. 10:00–11:00 B07/214, 11:00–12:00 B07/217, 11:00–12:00 B07/214, 12:00–12:30 B07/214, Pá 27. 10. 10:00–11:00 B07/214, 11:00–12:00 B07/214, 11:00–12:00 B07/217, 12:00–12:30 B07/214, Pá 3. 11. 10:00–11:00 B07/214, 11:00–12:00 B07/217, 11:00–12:00 B07/214, ...
aVLBI0121c/39: St 20. 9. 11:30–12:30 B07/214, 12:30–13:30 B07/217, 12:30–13:30 B07/214, 13:30–14:00 B07/214, St 27. 9. 11:30–12:30 B07/214, 12:30–13:30 B07/217, 12:30–13:30 B07/214, 13:30–14:00 B07/214, St 4. 10. 11:30–12:30 B07/214, 12:30–13:30 B07/217, 12:30–13:30 B07/214, 13:30–14:00 B07/214, St 11. 10. 11:30–12:30 B07/214, 12:30–13:30 B07/217, 12:30–13:30 B07/214, 13:30–14:00 B07/214, St 18. 10. 11:30–12:30 B07/214, 12:30–13:30 B07/214, 12:30–13:30 B07/217, 13:30–14:00 B07/214, St 25. 10. 11:30–12:30 B07/214, 12:30–13:30 B07/217, 12:30–13:30 B07/214, 13:30–14:00 B07/214, St 1. 11. 11:30–12:30 B07/214, 12:30–13:30 B07/217, 12:30–13:30 B07/214, ...
Předpoklady
Knowledge of high-school biology on the level of Overview of High School Biology (https://is.muni.cz/auth/do/med/el/overview/overview_ENG.qwarp) or similar is required.
Omezení zápisu do předmětu
Předmět je určen pouze studentům mateřských oborů.
Mateřské obory/plány
Cíle předmětu
The main objectives of the course are:
- learning how to use the light microscope to observe prokaryotic and eukaryotic cells and various cellular structures and processes
- ability to assess the risk of numerical and structural aberrations due to meiotic non-disjunctions and chromosomal translocations
- understanding of methods for assessing the cell cycle, mitosis, meiosis and cell death
Výstupy z učení
After completing the course, the student will be able to:
- operate the light microscope
- perform some of the basic cytochemical staining techniques in the observation of bacterial and human cells
- explain the basic principles and use of electron microscopy
- describe the basic techniques and applications of tissue and cell cultures
- deduce the impact of selected DNA mutations on the primary structure of proteins
- explain the methodology of assembling and examining the karyotype and its use, and evaluate basic numerical and structural aberrations in assigned human karyotypes
- evaluate the risk of numerical and structural aberrations resulting from meiotic non-disjunction and chromosomal translocations
- use some of the basic techniques of molecular biology to monitor the cell cycle and cell death
- describe the stages of cell division
Osnova
  • Week 1: Instructions. Non-cellular organisms and infectious agents
  • Week 2: Prokaryotic cells, basics of light microscopy
  • Week 3: Microscopic observation of eukaryotic cells
  • Week 4: Principles of electron microscopy and cellular ultrastructure
  • Week 5: Study of DNA damage
  • Week 6: Control test 1 (knowledge of the weeks 1 to 5 from practices and lectures) + pipetting workshop
  • Week 7: Human karyotype and chromosomal aberrations
  • Week 8: DNA structure, gene expression and DNA replication
  • Week 9: In vitro culture of human cells
  • Week 10: Methods for studying cell cycle
  • Week 11: Mitosis and meiosis observation under a light microscope
  • Week 12: Methods for studying cell death
  • Week 13: Control test 2 (knowledge of the weeks 7 to 12 - from practices and lectures) + microscopic exam
  • Week 14: no practice - dissection week, re-sit of control tests
Literatura
    povinná literatura
  • Actual protocols for practices are provided in electronic form in the Information System of the Masaryk University (IS): Study Materials of the course aVLBI0121c
Výukové metody
laboratory practice, class discussion
Metody hodnocení
Requirements for course completion: full attendance in the practices (1 absence, excused or unexcused, is allowed); all protocols completed (also for missed lessons) and checked and signed by appropriate teachers; successfully passed two written control tests during the semester. If you do not pass the control tests and their re-sit, you have to pass the final test (so-called Credit test) based on knowledge of the entire semester's lectures and practices.
In case of a student’s late arrival to the practice or poor activity at the practice, the student is required to write an essay the length of 2 pages on a given topic. Same for the case of 2nd and any additional absence in practices (excused or unexcused). Find the instructions for essay writing in the Course-related instructions in the IS.
In case of 3 absences (or more than 3 absences all excused by the Office for Studies within five days from the beginning of the absence and introduced to the Information System), it is addressed individually, and course-unit credit is awarded only after the proof of the student's knowledge of the entire semester topics (Credit test, see above).
Course-unit credit is not awarded in the case of 4 or more unexcused absences.
Vyučovací jazyk
Angličtina
Navazující předměty
Informace učitele
https://is.muni.cz/auth/el/med/podzim2023/aVLBI0121c/index.qwarp
Class attendance is mandatory. Classes have a form of practical exercises and take place every week. What to bring to each practice: printed protocol for the respective practice, your own writing materials. Download the protocol for each practice from the Study materials in the IS, and study it in advance. Lab coats and disposable gloves are not required. Please, bring your lab shoes/slippers.
Substitution of practices: In exceptional cases (illness, appointment at the doctor’s or foreign policy, 1 or 2 times per semester as maximum) students can arrange a substitution with another group. To arrange a substitution, write an e-mail to the course contact person at least 24 hours before your planned substitution and specify the group (date and time) you would like to attend instead. Substitution is only possible on the same teaching week. When the capacity of the group you intended to substitute with is fully used, the substitution does not need to be approved. Repeated substitution with other groups is not allowed.


Complete Biology instructions to be found at the following link: https://is.muni.cz/auth/el/med/podzim2023/aVLBI0121c/op/Biology_practices_instructions_aVL_autumn_2023.pdf?predmet=1514310

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Předmět je vyučován každoročně.
Nachází se v prerekvizitách jiných předmětů
Předmět je zařazen také v obdobích podzim 2015, podzim 2016, podzim 2017, podzim 2018, podzim 2019, podzim 2020, podzim 2021, podzim 2022, podzim 2024.