CH2BP_2P8P Organic Chemistry 1

Faculty of Education
Spring 2010
Extent and Intensity
1/0/0. 2 credit(s). Type of Completion: k (colloquium).
Teacher(s)
Mgr. Jiří Šibor, Ph.D. (lecturer)
Guaranteed by
Mgr. Jiří Šibor, Ph.D.
Department of Physics, Chemistry and Vocational Education – Faculty of Education
Contact Person: Helena Pelcová
Timetable
Wed 7:00–7:45 učebna 7
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
At the end of this course, student should be able to: understand and be able to explains structure and reactivity basic relationships of hydrocarbons; use data to organic chemistry problem solutions independently; make reasoned decisions about HC reactivity; formulate a reasoned differential diagnosis for products deduction of similar reactions; interpret HC characteristics.
Syllabus
  • The subject of organic chemistry. Nomenclature of organic chemistry. Name of compounds for-mation. Chemical bonds and bonding in organic molecules. Hybridization of the carbon atom, bon-ding energy, bond length, polarity of the chemical bond. Inductive and mesomeric effects, conjugation. Steric effects. General criteria of chemical reaction - reaction kinetics, reaction profiles and mecha-nism. Activation energy and enthalpy of the reaction. Chemical. Acidity and basicity. Arrhenius, Brøn-sted and Lewis explanation, acids and bases, pKa and pH. Spectral properties of organic com-pounds. Electronic spectra. Infrared spectroscopy, Nuclear magmetic resonance, mass spectroscopy. Alkanes and cycloalkanes. Chain isomerie, conformation analysis of alkanes and cycloalkanes. Fu-sed cyclic systems. Newmann projection. cis-trans- Isomerism of cycloalkanes. Radical reactions as typical reactions of this system. Summary of radical reactions. Optical activity and symmetry of molecules. Chiral molecules, conditions of chirality. Methods of space objects presentation. Enantio-mers, optical activity, specific rotation and its measurement, optical purity, racemic mixture. Molecules with more than one stereocenter. Cahn, Ingold, Prelog rules. Alkenes, stereochemistry of double bond, cis-trans and E-Z nomenclature. Addition reactions, their summary with attention to the stereo-chemistry and mechanism. Polymerizations. Dienes and polyenes (cumulated, isolated, conjugated). Reactions of conjugated dienes, conditions and mechanism of 1,2- and 1,4-addition. Isoprenoides (monoterpenes, sesquiterpenes, di-, tri- and tetraterpenes, carotenes). Steroids. Pericyclic reacti-ons - electrocyclic reactions, cycloaddition reactions, the rules of their realization, sigmatropic rear-rangements. Alkynes and their structure. Properties of the triple bond, addition reactions (electrophilic and nucleophilic additions), acidity of the hydrogen atoms bound on sp- carbon. Aromatic com-pounds.The phenomenon of aromaticity and its properties. Nonbenzoid aromates (polycyclic aroma-tes, annulenes, aromatic ions.} Mechanism of aromatic electrophilic substitution. Summary of electro-philic reactions, formation of electrophilic reagents. Effect of substituents on the reactivity and orien-tation. Hammet equation, sigma and rho constants. Ipso substitution. Nucleophilic substitution on the aromatic ring (SN1, SN2, elimination-addition mechanism). Conditions for addition reactions and reacti-ons of oxidation. Substitution a other reactions on fused aromatic compounds.
Literature
  • POTÁČEK, Milan. Organická chemie : pro biology. 3., opr. vyd. Brno: Masarykova univerzita, 2002, 208 s. ISBN 8021028505. info
  • MCMURRY, John. Fundamentals of organic chemistry. 4th ed. Pacific Grove: Brooks/Cole publishing company, 1998, xxii, 566,. ISBN 0-534-35245-4. info
  • KOVÁČ, Jaroslav, Štefan KOVÁČ and Ľubor FIŠERA. Organická chémia. 2. vyd. Bratislava: Vydavateľstvo STU, 1995, s. 276-629. ISBN 80-227-0791-0. info
  • POTÁČEK, Milan. Organická chemie : pro biology. 1. vyd. Brno: Vydavatelství Masarykovy univerzity, 1995, 208 s. ISBN 8021011254. info
  • SOLOMONS, T. W. Graham. Organic chemistry. 5th ed. New York: John Wiley & Sons, 1992, 1198 s. ISBN 0471552232. info
  • MACHÁČEK, Vladimír, Josef PANCHARTEK and Oldřich PYTELA. Organická chemie. Vyd. 1. Pardubice: Vysoká škola chemicko-technologická, 1991, s. 277-571. ISBN 80-85113-26-0. info
  • HRNČIAR, Pavol. Organická chémia. 3., preprac. vyd. Bratislava: Slovenské pedagogické nakladateľstvo, 1990, 708 s. ISBN 8008000287. info
  • MACHÁČEK, Vladimír and Josef PANCHARTEK. Organická chemie. 1. vyd. Pardubice: Vysoká škola chemicko-technologická, 1989, 276 s. ISBN 80-85113-08-2. info
  • ORCHIN, Milton. Organická chemie : příruční naučný slovník. Translated by Zdeněk Kafka - František Zemánek. 1. vyd. Praha: Státní nakladatelství technické literatury, 1986, 550 s. URL info
  • ČERVINKA, Otakar, Václav DĚDEK and Miloslav FERLES. Organická chemie. 3., nezměn. vyd. Praha: Státní nakladatelství technické literatury, 1982, 791 s. info
  • BUCHAR, Eugen, Jaroslav DOUBRAVA and Tibor LIPTHAY. Organická chemie : pro pedagogické fakulty. 1. vyd. Praha: Státní pedagogické nakladatelství, 1966, 355 s. info
Teaching methods
lectures
theoretical preparation
Assessment methods
Completion: written test - performance 70 %
colloquium
Language of instruction
Czech
Further Comments
The course can also be completed outside the examination period.
The course is taught annually.
The course is also listed under the following terms Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2011, Spring 2012, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, Spring 2018.
  • Enrolment Statistics (Spring 2010, recent)
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