FAFK1_14 Pharmacokinetics

Farmaceutická fakulta
jaro 2025
Rozsah
1/1/0. 3 kr. Ukončení: zk.
Vyučováno kontaktně
Vyučující
PharmDr. Tereza Kauerová, Ph.D. (přednášející)
doc. PharmDr. Peter Kollár, Ph.D. (přednášející)
Mgr. Martina Čudová (přednášející)
Mgr. Jana Melicharová (přednášející)
PharmDr. Tereza Kauerová, Ph.D. (cvičící)
doc. PharmDr. Peter Kollár, Ph.D. (cvičící)
Mgr. Martina Čudová (cvičící)
Mgr. Jana Melicharová (cvičící)
Garance
PharmDr. Tereza Kauerová, Ph.D.
Ústav farmakologie a toxikologie – Ústavy – Farmaceutická fakulta
Omezení zápisu do předmětu
Předmět je určen pouze studentům mateřských oborů.

Předmět si smí zapsat nejvýše 15 stud.
Momentální stav registrace a zápisu: zapsáno: 0/15, pouze zareg.: 0/15
Mateřské obory/plány
Cíle předmětu
Pharmacokinetics course deals with the fundamental principles of absorption, distribution, metabolism, and the elimination of drugs by the human body in time as well as clinical application, including case studies of commonly dosed drugs. Basic aim of education in Pharmacokinetics for students of pharmacy is getting deep knowledge in processes, which take place in relation to time course of drug after administration.
Understanding of pharmacokinetics patterns is important for insight into rational drug dosage in clinical practise. Application of the pharmacokinetic theory to clinical problems involved in optimizing and monitoring drug use in patients is important part of pharmacists work.
Výstupy z učení
After completing the course the student is able to explain the general rules regarding the pharmacokinetic processess and clinical significance and application od pharmacokinetic parameters. Student can also define and characterize different factors affecting the drug kinetics and thus pharmacotherapy. The student will be able to apply the acquired knowledge in a safe and effective pharmacotherapy.
Osnova
  • Introduction to pharmacokinetics (pharmacokinetic processes,basic pharmacokinetic principles)
    Description of the pharmacokinetic processes (absorption, distribution, metabolism, and the excretion of drugs)

    Pharmacokinetic parameters
    (description of pharmacokinetic parameters and their clinical importance)

    Factors of non-genetic origin affecting the drug kinetics
    Factors of genetic origin affecting the drug kinetics

    Pharmacokinetic interactions - description
    Pharmacokinetic interactions - casuistics solution

    Bioequivalence. Pharmacokinetics in the clinical trials.

    TDM - Therapeutic Drug Monitoring (Description and general principles, methodic and procedures of TDM in clinical practice)

    Special kinetics: Cytostatics
    Special kinetics: Antibiotics
Literatura
    povinná literatura
  • Whalen K. Lippincott Illustrated Reviews: Pharmacology, 7th edition. Lippincott Williams & Wilkins, USA, 2018. ISBN 978-1496384133. info
  • Humphrey P. Rang, Maureen M. Dale, James M. Ritter and Rod J. Fl. Rang & Dale's Pharmacology, 8th Edition. 2016. ISBN 978-0702053627. info
    doporučená literatura
  • Trevor A, Katzung B, Masters S., Knuidering-Hall M. Katzung & Trevor's Pharmacology Examination and Board Review. McGraw-Hill Medical, 2012. ISBN 0071789235. info
  • Katzung BG. Basic and Clinical Pharmacology. McGraw-Hill Medical, 2011. ISBN 978-0071764018. info
Výukové metody
lectures, seminars
Metody hodnocení
The criterion for passing the course is to fulfill the attendance requirement and then to pass the exam test. The condition for passing the exam test is to achieve at least 55% of the maximum possible number of points.
Vyučovací jazyk
Angličtina
Informace učitele
Conditions for successful completion of the course and obtaining credits are as follows: 1. Fulfill the course attendance. The absence will be excused by letter of absence or the compensation for the absence would be in the form of a seminar paper on a topic identical to the topic, which a student could not attend. In the case of a long-term serious absence, it will be dealt with individually. 2. To score at least 55% to pass the exam test.
Další komentáře
Předmět je dovoleno ukončit i mimo zkouškové období.
Předmět je zařazen také v obdobích jaro 2020, jaro 2022, jaro 2023, jaro 2024.