F1FO1_13 Dosage Forms and Biopharmacy I

Faculty of Pharmacy
Autumn 2021
Extent and Intensity
3/6/0. 5 credit(s). Type of Completion: z (credit).
Teacher(s)
doc. PharmDr. Aleš Franc, Ph.D. (lecturer)
doc. PharmDr. Kateřina Kubová, Ph.D. (lecturer)
doc. PharmDr. Ruta Masteiková, CSc. (lecturer)
PharmDr. Kateřina Brückner, Ph.D. (seminar tutor)
PharmDr. Nicole Fülöpová (seminar tutor)
PharmDr. Martina Holická, Ph.D. (seminar tutor)
doc. PharmDr. Jan Gajdziok, Ph.D. (lecturer)
PharmDr. Miroslava Pavelková, Ph.D. (lecturer)
PharmDr. Jakub Vysloužil, Ph.D. (lecturer)
PharmDr. Dagmar Blaháčková (seminar tutor)
PharmDr. Hana Hořavová (seminar tutor)
Mgr. Natália Janigová (seminar tutor)
PharmDr. Andrea Peštálová (seminar tutor)
PharmDr. Jiří Zeman, Ph.D. (seminar tutor)
Guaranteed by
doc. PharmDr. Kateřina Kubová, Ph.D.
Department of Pharmaceutical Technology – Departments – Faculty of Pharmacy
Contact Person: doc. PharmDr. Kateřina Kubová, Ph.D.
Supplier department: Department of Pharmaceutical Technology – Departments – Faculty of Pharmacy
Timetable
Thu 12:45–15:15 44-056
  • Timetable of Seminar Groups:
F1FO1_13/01: Mon 7:30–9:10 18-122, Mon 9:10–12:30 18-138, M. Pavelková
F1FO1_13/02: Mon 7:30–12:30 18-107, M. Holická
F1FO1_13/03: Mon 13:00–14:40 18-122, Mon 14:40–18:00 18-107, K. Kubová
F1FO1_13/04: Tue 7:30–9:10 18-122, Tue 9:10–12:30 18-138, K. Brückner
F1FO1_13/05: Tue 7:30–12:30 18-107, N. Fülöpová
F1FO1_13/06: Tue 13:00–14:40 18-122, Tue 14:40–18:00 18-138, J. Gajdziok
F1FO1_13/07: Tue 13:00–18:00 18-107, A. Peštálová
F1FO1_13/08: Wed 7:30–9:10 18-122, Wed 9:10–12:30 18-138, J. Vysloužil
F1FO1_13/09: Wed 7:30–12:30 18-107, N. Janigová
F1FO1_13/10: Wed 13:00–14:40 18-122, Wed 14:40–18:00 18-138, A. Franc
F1FO1_13/11: Wed 13:00–18:00 18-107, D. Blaháčková
F1FO1_13/12: Thu 7:30–12:30 18-107, H. Hořavová
Prerequisites (in Czech)
FAKULTA(FaF) || OBOR(MUSFaF)
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.

The capacity limit for the course is 160 student(s).
Current registration and enrolment status: enrolled: 1/160, only registered: 0/160
fields of study / plans the course is directly associated with
Course objectives
One of the main obligatory pharmaceutical disciplines dealing with preparation, manufacturing, and quality control of medicaments, including technological procedures, equipment, excipients, and appropriate analytical devices. It covers the influence of the application form on drug bioavailability.
Learning outcomes
After completing the course, a student will:
-know basic calculations for a given area;
- theoretically know the classification, requirements, excipients, technological process of preparation and production of liquid and semi-solid dosage forms, including their evaluation;
- know the essential aspects of dosage forms about the drug bioavailability
- practically know the preparation of liquid dosage forms in pharmacy conditions
Syllabus
  • SYLLABUS OF LECTURES
    1. Introduction into Medical Forms and Biopharmacy. Solutions: basic methods of preparation, quality evaluation.
    2. Excipients for preparation of liquid dosage forms (solutions). Water for pharmaceutical purposes.
    3. Sterilization techniques. Requirements for the preparation of sterile medications.
    4. Ophthalmic preparations - definition, classification, preparation, quality evaluation, the bioavailability of drugs from ophthalmic products.
    5. Preparations intended for nasal and ear application.
    6. Pharmaceutical emulsions - definition, classification, preparation, quality evaluation. Physical aspects of emulsions.
    7. Public holiday.
    8.Pharmaceutical suspensions - definition, classification, preparation, quality evaluation.
    9. Incompatibilities in liquid dosage forms.
    10. Powders, classification, particle size, and the influence of particle size on the bioavailability of drugs, preparation, application, and quality evaluation.
    11. Herbal drug preparations - definition, classification, preparation and production, quality assessment.
    12. Parenteral dosage forms.
    13. Topical semisolid preparations: definition, classification, properties, excipients.
    14. Topical semisolid preparations: preparation and quality evaluation.

    PRACTICAL TRAINING
    1. Introduction to the practical training. Pharmaceutical calculations.
    2. Medicinal solutions: preparation at room and higher temperature, evaluation.
    3. Medicinal solutions: preparation by solubilization and chemical reaction, evaluation.
    4. Aromatic waters and spirits. Syrups. Infusions and decoctions. Mucilagines. Preparation and evaluation.
    5. Eye drops. Preparation and evaluation.
    6. Nasal and ear drops. Preparation and evaluation.
    7. Emulsions. Preparation and evaluation.
    8. Suspensions. Preparation and evaluation.
    9. Consultation exercise on liquid dosage forms.
    10. Preparation of liquid dosage forms according to prescriptions.
    11. Divided and non-divided pharmaceutical powders. Preparation and evaluation.
    12. Alternative training.
    13. Test and check training.
    14. Awarding credits.

Literature
    required literature
  • Český lékopis - platné vydání a doplňky. info
  • Komárek, P., Rabišková, M. Technologie léků. Galén, Praha, 2006. ISBN 80-7262-423-7. info
    not specified
  • Časopis Česká a slovenská farmacie. info
  • Zathurecký, L., Chalabala, M., Janků, I., Modr., Z. Biofarmácia a farmakokinetika. Osveta Martin, 1989. ISBN 80-217-0068-8. info
  • Chalabala, M., Heinrich, J. Základy výroby a tvorby liekov. Osveta Martin, 1988. info
Teaching methods
Lectures
Lab training
Homework
Assessment methods
Written test
Systematic observation of student during lab training
Practical test of student skills
Language of instruction
Czech
Follow-Up Courses
Further comments (probably available only in Czech)
Study Materials
The course can also be completed outside the examination period.
Listed among pre-requisites of other courses
Teacher's information
Lectures are recommended due to lack of suitable literature.
Lab training are obligatory (100 %).
The course is also listed under the following terms Autumn 2020, Autumn 2022, Autumn 2023, Autumn 2024.
  • Enrolment Statistics (Autumn 2021, recent)
  • Permalink: https://is.muni.cz/course/pharm/autumn2021/F1FO1_13