FaF:F1FG1_12 Pharmacognosy I - Course Information
F1FG1_12 Pharmacognosy I
Faculty of PharmacyAutumn 2024
- Extent and Intensity
- 2/4/0. 4 credit(s). Type of Completion: z (credit).
In-person direct teaching - Teacher(s)
- doc. PharmDr. Renata Kubínová, Ph.D. (lecturer)
prof. RNDr. Václav Suchý, DrSc., dr. h.c. (lecturer)
prof. PharmDr. Karel Šmejkal, Ph.D. (lecturer)
PharmDr. Ivana Daňková, Ph.D. (seminar tutor)
PharmDr. Margita Dvorská, Ph.D. (seminar tutor)
Mgr. Petra Herczogová (seminar tutor)
PharmDr. Dagmar Jankovská, Ph.D. (seminar tutor)
doc. PharmDr. Renata Kubínová, Ph.D. (seminar tutor)
PharmDr. Milan Malaník, Ph.D. (seminar tutor)
PharmDr. Lenka Molčanová, Ph.D. (seminar tutor)
PharmDr. Alice Sychrová, Ph.D. (seminar tutor)
Mgr. Ing. Jiří Václavík, Ph.D. (seminar tutor)
PharmDr. Gabriela Škovranová, Ph.D. (assistant) - Guaranteed by
- prof. PharmDr. Karel Šmejkal, Ph.D.
Department of Natural Drugs – Departments – Faculty of Pharmacy
Supplier department: Department of Natural Drugs – Departments – Faculty of Pharmacy - Timetable
- Wed 9:35–11:15 44-056
- Timetable of Seminar Groups:
F1FG1_12/02: Mon 15:35–18:55 45-321, J. Václavík
F1FG1_12/03: Tue 7:00–10:20 45-321, M. Dvorská
F1FG1_12/04: Tue 10:35–13:55 45-321, D. Jankovská
F1FG1_12/05: Thu 12:30–15:50 45-321, L. Molčanová
F1FG1_12/06: Thu 16:00–19:20 45-321, M. Malaník - Prerequisites
- FAKULTA(FaF) || OBOR(MUSFaF)
The students should have passed basic subject touching organic chemistry, analytical chemistry, biology, botany, and physiology. - Course Enrolment Limitations
- The course is only offered to the students of the study fields the course is directly associated with.
The capacity limit for the course is 160 student(s).
Current registration and enrolment status: enrolled: 117/160, only registered: 0/160 - fields of study / plans the course is directly associated with
- Pharmacy (programme FaF, M-FARM)
- Multidisciplinary studies at Faculty of Pharmacy (programme CST, KOS)
- Vzdělávání v jednotlivých předmětech (programme FaF, C-CV)
- Course objectives
- Objectives of Pharmacognosy are to impart knowledges of those drugs of biological origin and their constituents that are of value for their therapeutic, profylactic and diagnostic use in the human and veterinary medicine.
Its scope includes the study of the physical, chemical, biochemical and biological properties of drugs, drug substances, or potential drugs or drug substances of natural origin as well as the search for new drugs from natural sources. Research problems in pharmacognosy include studies in the areas of phytochemistry, microbial chemistry, biosynthesis, biotransformation, chemotaxonomy, and other biological and chemical sciences.
Pharmacognosy represents a highly interdisciplinary science which is one of five major areas of pharmaceutical education. - Learning outcomes
- The student must be able to microscopically and macroscopically identify selected drugs, know their main content substances, use, basic biosynthetic reactions, basal classes of secondary metabolites. Know the main plants used in the pharmacy. Chemical characteristics of secondary metabolites, basic knowledge of structure-activity relationships, basic knowledge of adverse effects and interactions.
- Syllabus
- Syllabus of lectures
" Introduction and historical background.
" Generalities on collection, preservation, evaluation, and factors that influence the quality and price of drugs.
" Systemes for classification and characterization of natural drugs.
" Methodology of pharmacognosy.
" Natural drugs in relation to the European Pharmacopoeia.
" Biosynthesis of natural compounds, primary and secondary metabolism, precursors, relationship.
" Carbohydrates and their derivatives. Monosaccharides, oligosaccharides, polysaccharides (starches, mucilages). Polysaccharides from microorganisms, fungi, and algae, glycoconjugates. Lipids.
" General characterization of the individual class of plant constituents:
glycosides, essential oils, terpenoids and steroids, bitter substances, alkaloids, tannins, flavonoids, compounds with hormonal activity, vitamins, coloring principles, sweeteners.
" Antibiotics, macrolides, cytostatics, important drugs of animal origin.
" Natural compounds derived from the shikimic acid.
" Natural compounds derived from the acetic acid.
" Natural compounds derived from mevalonic acid.
" Natural compounds derived from the aminoacids.
Practical classes
1.
Drugs, the terminology of drugs, pharmacopeia, Pharmacognostic control tests of identity and purity, Preparation of temporary and durable preparations, Micro and macroscopic examination of drugs, Classification of drugs according to the pharmacological effects, Survey of modern literature and databases
2.
Powders - starches, Faex medicinalis, Lycopodium
Lana gossypii depurata, Cellulosum ligni
Agar, Gelatina animalis, Cera alba, Cera lanae, Cetaceum, Guttapercha, Cautschuc, Mel, Propolis
Fibers, Natural antidiabetics
3.
Lichen islandicus, Secale cornutum
Filicis maris rhizoma
Sarsaparillae radix, Veratri albi radix,
Calami aromatici rhizoma
Balsamum peruvianum, Camphora, Carbo adsorbens, Chrysarobinum, Gummi arabicum, Gummiresina myrha, Fagi pix, Lithanthracis pix, Tragacantha, Aconiti tuber, Colchici tuber
4.
Roots of dicotyledonous plants I
Rhizomes of dicotyledonous plants
Macro: Angelicae radix, Bardanae radix, Graminis rhizoma, Inulae rhizoma, Primulae radix, Rhei radix, Saponariae radix, Sarsaparillae radix, Valerianae radix, Echinaceae angustifoliae radix
5.
Roots of dicotyledonous plants II
Macro: Zingiberis radix, Ginseng radix, Betulae folium, Digitalis lanatae folium, Digitalis purpureae folium, Farfarae folium, Fragariae folium, Hamamelidis folium, Malvae folium, Rubi fruticosi folium, Rubi idaei folium, Eleutherococci radix, Rusci radix
test I
6.
Barks
Monofacial leaves
Macro: Cinnamomi chinensis cortex, Condurango cortex, Rhamni purshianae cortex, Salicis cortex, Bucco folium, Juglandis folium, Lauri folium, Myrtilli folium, Vitis idaeae folium, Quassiae lignum
7.
Bifacial leaves
Macro: Crataegi folium cum flore, Plantaginis folium, Ribes nigri folium, Adonidis herba, Agrimoniae herba, Alchemillae herba, Centaurii herba, Herniariae herba, Hyperici herba, Hyssopi herba, Ginkgo folium, Hederae folium, Oleae folium
8.
Leves, herbs
Macro: Marrubii herba, Millefolii herba, Origani herba, Polygoni avicularis herba, Salviae herba, Serpylli herba, Urticae herba, Visci albi herba, Solidaginis virgaureae herba, Tanaceti parthenii herba
9.
Herbs, flowers
Macro: Arnicae flos, Caryophylli flos, Farfarae flos, Lamii albi flos, Lavandulae flos, Malvae flos, Primulae flos, Sambuci flos, Tiliae flos, Hibisci sabdariffae flos, Lupuli flos
10.
Fruits
Macro: Avenae fructus, Capsici fructus, Carvi fructus, Crataegi fructus, Cynosbati fructus, Juniperi fructus, Myrtilli fructus, Papaveris fructus, Phaseoli sine semine fructus, Sennae fructus
test II
11.
Seeds, Pericarp
Macro: Colae semen, Colchici semen, Lini semen, Ricini semen, Sinapis semen
Selection of newly introduced drugs.
- Syllabus of lectures
- Literature
- required literature
- Šmejkal, K., Kubínová, R., Suchý, V. Farmakognozie část obecná. 2016. ISBN 978-80-7305-785-5. info
- Kubínová R., Jankovská D. Obrazový atlas farmaceuticky významných drog. Brno, 2013. ISBN 978-80-7305-667-4. info
- Tomko, J. a kol. Farmakognózia. Osveta, 1999. info
- recommended literature
- ŠMEJKAL, Karel, Zuzana HANÁKOVÁ and Markéta GAZDOVÁ. Praktické fytochemické úlohy pro farmakognozii a fytochemii Návody pro laboratorní cvičení. 2024. URL info
- KUBÍNOVÁ, Renata and Dagmar JANKOVSKÁ. Vybrané mikroskopické preparáty farmaceuticky významných drog. 2024. URL info
- Český lékopis 2017. 2017. ISBN 859-404-924-045-6. info
- Nagy, M., Mučaji, P., Grančai, D. Farmakognózia. 2017. ISBN 9788089631643. info
- Samuelsson G., Bohlin L. Drugs of Natural Origin. A Treatise of Pharmacognosy. 7th revised edition. 2015. info
- Grančai, D., Nagy, M., Mučaji, P. Farmakognózia - Biogenéza prírodných látok. 2015. ISBN 978-80-8063-368-4. info
- Suchý V. Fytofarmaka. In Kuchař M. ed. Farmaceutický encyklopedický slovník. Praha, 2014. info
- Wichtl M. Herbal Drugs and Phytopharmaceuticals. 2002. info
- Dewick P.M. Medicinal Natural Products. 2002. info
- Bruneton J. Pharmacognosy, Phytochemistry, Medicinal Plants. 1999. info
- Mika, K. Fytoterapia. Osveta, 1988. info
- Kindl, H., Vöber, B. Biochemie rostlin. Academia Praha, 1981. info
- Teaching methods
- Lectures, practical classes
- Assessment methods
- Written tests
- Language of instruction
- Czech
- Further comments (probably available only in Czech)
- Study Materials
The course can also be completed outside the examination period. - Listed among pre-requisites of other courses
- Teacher's information
- Assesment methods: 100% attendance at practical exercises, min. 60% success rate of each test, submission of protocols for completed assignments
- Enrolment Statistics (recent)
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