F1KB1_14 Clinical Biochemistry

Faculty of Pharmacy
Autumn 2024
Extent and Intensity
1/1/0. 3 credit(s). Type of Completion: zk (examination).
In-person direct teaching
Teacher(s)
Ing. Michal Karpíšek, Ph.D. (lecturer)
Ing. Michal Karpíšek, Ph.D. (seminar tutor)
PharmDr. Bc. Hana Kotolová, Ph.D. (seminar tutor)
Guaranteed by
Ing. Michal Karpíšek, Ph.D.
Department of Pharmacology and Toxicology – Departments – Faculty of Pharmacy
Supplier department: Department of Pharmacology and Toxicology – Departments – Faculty of Pharmacy
Timetable
Mon 28. 10. to Fri 13. 12. Tue 16:00–17:40 44-249
  • Timetable of Seminar Groups:
F1KB1_14/01: Mon 28. 10. to Fri 13. 12. Tue 17:40–19:20 44-249, Tue 17:40–19:20 44-140, M. Karpíšek
Prerequisites (in Czech)
FAKULTA(FaF) || OBOR(MUSFaF)
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.

The capacity limit for the course is 25 student(s).
Current registration and enrolment status: enrolled: 23/25, only registered: 0/25
fields of study / plans the course is directly associated with
Course objectives
Clinical Biochemistry is an elective course that introduces pharmacy students to the basic in methods of clinical biochemistry, corresponding reference values and clinical interpretation. The methods section aims to provide information on the principles of selected methods in the biochemistry laboratory. Special emphasis is placed on new approaches used in clinical pharmacy. The clinical section aims to provide comprehensive information from indication to laboratory diagnosis for selected pathophysiological conditions, which will develop students' critical thinking and navigate the requirements of laboratory analysis. The aim of the practical is to introduce students to the specific requirements of biochemical analysis and to deepen general laboratory work habits.
Learning outcomes
After completing the clinical biochemistry course, the student will be familiar with the principles of basic clinical biochemistry methods and the requirements for clinical biochemistry laboratories. The course graduate will recognize pathological results and how to handle such results. In the practical part, the student will gain a basic overview of planning and performing laboratory measurements, their evaluation and an overview of how to interpret data.
Syllabus
  • 1/ Parameters of a certified laboratory, quality system, economics of biochemical laboratories, doctor-laboratory communication. Preanalytical-analytical-postanalytical phase of laboratory testing, immunochemical methods, TDM methods, pharmacogenetics methods. Instrumentation, automation. Evaluation of laboratory analysis. 2/ Energy metabolism, determination of glucose, DM, glycated haemoglobin, determination of cholesterol, triacylglycerols and apolipoproteins. Metabolic syndrome, atherosclerosis. Acid-base and electrolyte balance parameters. Laboratory indicators of liver, kidney, pancreatic function and cardiovascular damage. Toxicological analysis, monitoring of drug levels. Urinalysis. Examination of cerebrospinal fluid. Selected endocrine indicators and vitamins. Laboratory investigation of inflammation and infection. Autoimmunity, allergies. Tumor markers. DNA diagnostics. 3/ Practical exercises - selected methods in clinical biochemistry, annotated and independent performance of the method.
Literature
    recommended literature
  • Jaroslav Racek a kol. Klinická biochemie. 2006. info
    not specified
  • ZIMA, Tomáš. Laboratorní diagnostika. 2., dopl. a přeprac. vyd. Praha: Galén, 2007, xxxviii, 9. ISBN 9788024614236. info
Teaching methods
lectures, exercises
Assessment methods
Full participation in exercises is obligatory. Students may be allowed to pass the examination in a case of 100% attendance in exercises only. This subject will be terminated by the examination in written test form. In the case of failure the test students complete the subject by oral examination.
Language of instruction
Czech
Further Comments
The course can also be completed outside the examination period.
The course is also listed under the following terms Autumn 2020, Autumn 2021, Autumn 2022, Autumn 2023.
  • Enrolment Statistics (recent)
  • Permalink: https://is.muni.cz/course/pharm/autumn2024/F1KB1_14