Bi1508 Synthetic Biology

Faculty of Science
Autumn 2016
Extent and Intensity
2/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
Teacher(s)
prof. Mgr. Jiří Damborský, Dr. (lecturer)
Guaranteed by
prof. Mgr. Jiří Damborský, Dr.
Department of Experimental Biology – Biology Section – Faculty of Science
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science
Prerequisites
Bi1510 Mgr. state exam
Basic knowledge of biochemistry, microbiology, molecular biology and genetics.
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
The student will understand the nature of synthetic biology and will be able to name the examples of applications of synthetic biology at the end of this course. Students will have the theoretical foundation and a comprehensive overview of the field important for their future career in research laboratories, biomedical research and development or biotechnology industry.
Syllabus
  • 1) Opening lecture 2) High-throughput synthesis and DNA sequencing. 3) System biology, mathematical modeling of living systems, bioinformatic tools in synthetic biology. 4) Design and registration of novel biological components in synthetic biology, orthogonal systems. 5) Host organisms in synthetic biology, minimal genome and minimal cell, cell chases. 6) Synthetic genome, synthetic life (cell), tools for editation of genome. 7) Synthetic biology in metabolic engineering. 8) Biosensors, intercellular communication, de novo protein design. 9) Cell-free systems. 10) Ethical aspects of synthetic biology.
Literature
  • Synthetic biology : tools and applications. Edited by Huimin Zhao. Amsterdam: Elsevier, 2013, xviii, 333. ISBN 9780123944306. info
  • Synthetic biology : a primer. Edited by Geoff Baldwin. London: Imperial College Press, 2012, xiv, 179. ISBN 9781848168626. info
  • SCHMIDT, Markus. Synthetic biology : industrial and environmental applications. Weinheim: Wiley-Blackwell, 2012, xxvi, 240. ISBN 9783527331833. info
Teaching methods
The PowerPoint presentations are used, PDF materials for printing and notices are available before each course.
Assessment methods
Written test in the examination period.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course is taught annually.
The course is taught: every week.
General note: Předmět není v akademickém roce 2015/2016 vypisován.
The course is also listed under the following terms Autumn 2015.
  • Enrolment Statistics (recent)
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