Course Information

Bi5420 General virology

Faculty of Science
Spring 2025

Extent and Intensity

2/0/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
In-person direct teaching

Teacher(s)

prof. RNDr. Ivo Rudolf, Ph.D. (lecturer)

Guaranteed by

prof. RNDr. Ivo Rudolf, Ph.D.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Ivo Rudolf, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science

Prerequisites

( Bi4020 Molecular biology || NOW( Bi4020 Molecular biology )) && ( Bi4090 General microbiology || NOW( Bi4090 General microbiology ))
Course has been established for students of orientation Biology (special biology, molecular biology and genetics) and also to other potential participants interested in virology.

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 8 fields of study the course is directly associated with, display

Course objectives

At the end of the course, participant should repeat, translate and apply general terms operating in virology, describe basic structure and morphology of viruses, define and translate strategy of replication of viral genome and interpret current taxonomy of viruses. Participant of the course should also characterize important viral diseases of plants, invertebrates and vertebrates including humans and interpret state of the art methods and diagnostic tools used in virology. Participant will employ acquired skills in basic and applied research in virology or in diagnostic laboratories.

Learning outcomes

Syllabus

Introduction to general virology; specific terms in virology; history of virology; basic characteristic of viral particles (morphology and structure of viruses, enveloped and non-enveloped viruses); chemical composition of viruses (nucleic acids, proteins, other components of viral particles); stability of viruses in environment and inactivation of viruses (effect of temperature, pH, chemical reagents, radiation); strategy of replication of viral genome - on basis of nucleic acid type (dsDNA, ssDNA, dsRNA, +ssRNA; -ssRNA, +ssRNA-RT, dsDNA-RT); bacteriophages (lytic and lysogenic cycle); virophages; cyanophages; plant viruses; viroids; viruses of invertebrates; pathogenesis of viral diseases (definition of terms: disease, virulence, viraemia, persistent and latent infection); typical modes of virus spread in host organism including subsequent excretion of viruses from host; viral diseases of animals; imported viral infections; oncoviruses; host response to viral infection (nonspecific and specific immunity); immunization against viral diseases (active and passive approach); basic principles of vaccination; composition and types of vaccines; vaccination strategy; chemotherapy of viral diseases; direct and indirect diagnostics of viruses in clinical virology; surveillance of viral diseases; safety measures in virological laboratory; good laboratory praxis - handling with viruses; viruses and biotechnology; classification and nomenclature of viruses - characteristic of particular virus families with emphasis on medically important agents; prions and prion ´s diseases.

Literature

recommended literature

King, A.M.Q., Lefkowitz, E., Adams, M. J., Carstens, E. B. (2011). Virus Taxonomy: Ninth Report of the International Comittee on Taxonomy of Viruses, 1338 p.
COLLIER, L. H., Paul KELLAM and J. S. OXFORD. Human virology. 4th ed. Oxford: Oxford University Press, 2011, xiv, 365. ISBN 9780199570881. info
HUBÁLEK, Zdeněk and Ivo RUDOLF. Microbial Zoonoses and Sapronoses. 1st ed. Dordrecht-Heidelberg-London-New York: Springer, 2011, 457 pp. ISBN 978-90-481-9656-2. Available from: https://dx.doi.org/10.1007/978-90-481-9657-9. URL info

not specified

CARTER, John B. and Venetia A. SAUNDERS. Virology : principles and applications. 2nd ed. Chichester: Wiley, 2013, xxix, 364. ISBN 9781119991434. info
NORKIN, Leonard C. Virology : molecular biology and pathogenesis. Washington, D.C.: ASM Press, 2010, xxiii, 725. ISBN 9781555814533. info
MAHY, B. W. J. A dictionary of virology. 4th ed. Amsterdam: Elsevier, 2009, 510 s. ISBN 9780123737328. info
FLINT, S. Jane. Principles of virology. 3rd ed. Washington, DC: ASM Press, 2009, xx, 419. ISBN 9781555814809. info
RAJČÁNI, Július and Fedor ČIAMPOR. Lekárska virológia. 1. vyd. Bratislava: VEDA vydavateľstvo Slovenskej akadémie vied, 2006, 574 s. ISBN 8022409111. info
ROSYPAL, Stanislav. Úvod do molekulární biologie. Třetí inovované vydání. Brno, 2000, 300 pp. Díl III. Molekulární biologie virů. ISBN 80-902562-2-8. URL info

Teaching methods

Powerpoint presentation (slide projection) accompanied by showing of illustrations, schemes, photos and video projection. Students are continuously informed with "News in the field of Virology".

Assessment methods

Final evaluation is based on written test (Success rate 60%).

Language of instruction

Czech

Follow-Up Courses

Further comments (probably available only in Czech)

The course is taught annually.
The course is taught: every week.

Listed among pre-requisites of other courses

The course is also listed under the following terms Autumn 2002, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024.

Bi5420 General virology

Faculty of Science
Spring 2024

Extent and Intensity

2/0/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).

Teacher(s)

prof. RNDr. Ivo Rudolf, Ph.D. (lecturer)

Guaranteed by

Timetable

Mon 19. 2. to Sun 26. 5. Thu 8:00–9:50 B11/306

Prerequisites

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 8 fields of study the course is directly associated with, display

Course objectives

Learning outcomes

Syllabus

Introduction to general virology; specific terms in virology; history of virology; basic characteristic of viral particles (morphology and structure of viruses, enveloped and non-enveloped viruses); chemical composition of viruses (nucleic acids, proteins, other components of viral particles); stability of viruses in environment and inactivation of viruses (effect of temperature, pH, chemical reagents, radiation); strategy of replication of viral genome - on basis of nucleic acid type (dsDNA, ssDNA, dsRNA, +ssRNA; -ssRNA, +ssRNA-RT, dsDNA-RT); bacteriophages (lytic and lysogenic cycle); virophages; cyanophages; plant viruses; viroids; viruses of invertebrates; pathogenesis of viral diseases (definition of terms: disease, virulence, viraemia, persistent and latent infection); typical modes of virus spread in host organism including subsequent excretion of viruses from host; viral diseases of animals; imported viral infections; oncoviruses; host response to viral infection (nonspecific and specific immunity); immunization against viral diseases (active and passive approach); basic principles of vaccination; composition and types of vaccines; vaccination strategy; chemotherapy of viral diseases; direct and indirect diagnostics of viruses in clinical virology; surveillance of viral diseases; safety measures in virological laboratory; good laboratory praxis - handling with viruses; viruses and biotechnology; classification and nomenclature of viruses - characteristic of particular virus families with emphasis on medically important agents; prions and prion ´s diseases.

Literature

recommended literature

King, A.M.Q., Lefkowitz, E., Adams, M. J., Carstens, E. B. (2011). Virus Taxonomy: Ninth Report of the International Comittee on Taxonomy of Viruses, 1338 p.
COLLIER, L. H., Paul KELLAM and J. S. OXFORD. Human virology. 4th ed. Oxford: Oxford University Press, 2011, xiv, 365. ISBN 9780199570881. info
HUBÁLEK, Zdeněk and Ivo RUDOLF. Microbial Zoonoses and Sapronoses. 1st ed. Dordrecht-Heidelberg-London-New York: Springer, 2011, 457 pp. ISBN 978-90-481-9656-2. Available from: https://dx.doi.org/10.1007/978-90-481-9657-9. URL info

not specified

CARTER, John B. and Venetia A. SAUNDERS. Virology : principles and applications. 2nd ed. Chichester: Wiley, 2013, xxix, 364. ISBN 9781119991434. info
NORKIN, Leonard C. Virology : molecular biology and pathogenesis. Washington, D.C.: ASM Press, 2010, xxiii, 725. ISBN 9781555814533. info
MAHY, B. W. J. A dictionary of virology. 4th ed. Amsterdam: Elsevier, 2009, 510 s. ISBN 9780123737328. info
FLINT, S. Jane. Principles of virology. 3rd ed. Washington, DC: ASM Press, 2009, xx, 419. ISBN 9781555814809. info
RAJČÁNI, Július and Fedor ČIAMPOR. Lekárska virológia. 1. vyd. Bratislava: VEDA vydavateľstvo Slovenskej akadémie vied, 2006, 574 s. ISBN 8022409111. info
ROSYPAL, Stanislav. Úvod do molekulární biologie. Třetí inovované vydání. Brno, 2000, 300 pp. Díl III. Molekulární biologie virů. ISBN 80-902562-2-8. URL info

Teaching methods

Powerpoint presentation (slide projection) accompanied by showing of illustrations, schemes, photos and video projection. Students are continuously informed with "News in the field of Virology".

Assessment methods

Final evaluation is based on written test (Success rate 60%).

Language of instruction

Czech

Follow-Up Courses

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Listed among pre-requisites of other courses

Bi5420 General virology

Faculty of Science
Spring 2023

Extent and Intensity

2/0/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).

Teacher(s)

prof. RNDr. Ivo Rudolf, Ph.D. (lecturer)

Guaranteed by

prof. RNDr. Ivo Rudolf, Ph.D.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: Ing. Jiřina Kučerová, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science

Timetable

Thu 10:00–11:50 B11/306

Prerequisites

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 8 fields of study the course is directly associated with, display

Course objectives

Learning outcomes

Syllabus

Introduction to general virology; specific terms in virology; history of virology; basic characteristic of viral particles (morphology and structure of viruses, enveloped and non-enveloped viruses); chemical composition of viruses (nucleic acids, proteins, other components of viral particles); stability of viruses in environment and inactivation of viruses (effect of temperature, pH, chemical reagents, radiation); strategy of replication of viral genome - on basis of nucleic acid type (dsDNA, ssDNA, dsRNA, +ssRNA; -ssRNA, +ssRNA-RT, dsDNA-RT); bacteriophages (lytic and lysogenic cycle); virophages; cyanophages; plant viruses; viroids; viruses of invertebrates; pathogenesis of viral diseases (definition of terms: disease, virulence, viraemia, persistent and latent infection); typical modes of virus spread in host organism including subsequent excretion of viruses from host; viral diseases of animals; imported viral infections; oncoviruses; host response to viral infection (nonspecific and specific immunity); immunization against viral diseases (active and passive approach); basic principles of vaccination; composition and types of vaccines; vaccination strategy; chemotherapy of viral diseases; direct and indirect diagnostics of viruses in clinical virology; surveillance of viral diseases; safety measures in virological laboratory; good laboratory praxis - handling with viruses; viruses and biotechnology; classification and nomenclature of viruses - characteristic of particular virus families with emphasis on medically important agents; prions and prion ´s diseases.

Literature

recommended literature

King, A.M.Q., Lefkowitz, E., Adams, M. J., Carstens, E. B. (2011). Virus Taxonomy: Ninth Report of the International Comittee on Taxonomy of Viruses, 1338 p.
COLLIER, L. H., Paul KELLAM and J. S. OXFORD. Human virology. 4th ed. Oxford: Oxford University Press, 2011, xiv, 365. ISBN 9780199570881. info
HUBÁLEK, Zdeněk and Ivo RUDOLF. Microbial Zoonoses and Sapronoses. 1st ed. Dordrecht-Heidelberg-London-New York: Springer, 2011, 457 pp. ISBN 978-90-481-9656-2. Available from: https://dx.doi.org/10.1007/978-90-481-9657-9. URL info

not specified

CARTER, John B. and Venetia A. SAUNDERS. Virology : principles and applications. 2nd ed. Chichester: Wiley, 2013, xxix, 364. ISBN 9781119991434. info
NORKIN, Leonard C. Virology : molecular biology and pathogenesis. Washington, D.C.: ASM Press, 2010, xxiii, 725. ISBN 9781555814533. info
MAHY, B. W. J. A dictionary of virology. 4th ed. Amsterdam: Elsevier, 2009, 510 s. ISBN 9780123737328. info
FLINT, S. Jane. Principles of virology. 3rd ed. Washington, DC: ASM Press, 2009, xx, 419. ISBN 9781555814809. info
RAJČÁNI, Július and Fedor ČIAMPOR. Lekárska virológia. 1. vyd. Bratislava: VEDA vydavateľstvo Slovenskej akadémie vied, 2006, 574 s. ISBN 8022409111. info
ROSYPAL, Stanislav. Úvod do molekulární biologie. Třetí inovované vydání. Brno, 2000, 300 pp. Díl III. Molekulární biologie virů. ISBN 80-902562-2-8. URL info

Teaching methods

Powerpoint presentation (slide projection) accompanied by showing of illustrations, schemes, photos and video projection. Students are continuously informed with "News in the field of Virology".

Assessment methods

Final evaluation is based on written test (Success rate 60%).

Language of instruction

Czech

Follow-Up Courses

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Listed among pre-requisites of other courses

Bi5420 General virology

Faculty of Science
Spring 2022

Extent and Intensity

2/0/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).

Teacher(s)

prof. RNDr. Ivo Rudolf, Ph.D. (lecturer)

Guaranteed by

Timetable

Mon 8:00–9:50 B11/306

Prerequisites

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 8 fields of study the course is directly associated with, display

Course objectives

Learning outcomes

Syllabus

Introduction to general virology; specific terms in virology; history of virology; basic characteristic of viral particles (morphology and structure of viruses, enveloped and non-enveloped viruses); chemical composition of viruses (nucleic acids, proteins, other components of viral particles); stability of viruses in environment and inactivation of viruses (effect of temperature, pH, chemical reagents, radiation); strategy of replication of viral genome - on basis of nucleic acid type (dsDNA, ssDNA, dsRNA, +ssRNA; -ssRNA, +ssRNA-RT, dsDNA-RT); bacteriophages (lytic and lysogenic cycle); virophages; cyanophages; plant viruses; viroids; viruses of invertebrates; pathogenesis of viral diseases (definition of terms: disease, virulence, viraemia, persistent and latent infection); typical modes of virus spread in host organism including subsequent excretion of viruses from host; viral diseases of animals; imported viral infections; oncoviruses; host response to viral infection (nonspecific and specific immunity); immunization against viral diseases (active and passive approach); basic principles of vaccination; composition and types of vaccines; vaccination strategy; chemotherapy of viral diseases; direct and indirect diagnostics of viruses in clinical virology; surveillance of viral diseases; safety measures in virological laboratory; good laboratory praxis - handling with viruses; viruses and biotechnology; classification and nomenclature of viruses - characteristic of particular virus families with emphasis on medically important agents; prions and prion ´s diseases.

Literature

recommended literature

King, A.M.Q., Lefkowitz, E., Adams, M. J., Carstens, E. B. (2011). Virus Taxonomy: Ninth Report of the International Comittee on Taxonomy of Viruses, 1338 p.
COLLIER, L. H., Paul KELLAM and J. S. OXFORD. Human virology. 4th ed. Oxford: Oxford University Press, 2011, xiv, 365. ISBN 9780199570881. info
HUBÁLEK, Zdeněk and Ivo RUDOLF. Microbial Zoonoses and Sapronoses. 1st ed. Dordrecht-Heidelberg-London-New York: Springer, 2011, 457 pp. ISBN 978-90-481-9656-2. Available from: https://dx.doi.org/10.1007/978-90-481-9657-9. URL info

not specified

CARTER, John B. and Venetia A. SAUNDERS. Virology : principles and applications. 2nd ed. Chichester: Wiley, 2013, xxix, 364. ISBN 9781119991434. info
NORKIN, Leonard C. Virology : molecular biology and pathogenesis. Washington, D.C.: ASM Press, 2010, xxiii, 725. ISBN 9781555814533. info
MAHY, B. W. J. A dictionary of virology. 4th ed. Amsterdam: Elsevier, 2009, 510 s. ISBN 9780123737328. info
FLINT, S. Jane. Principles of virology. 3rd ed. Washington, DC: ASM Press, 2009, xx, 419. ISBN 9781555814809. info
RAJČÁNI, Július and Fedor ČIAMPOR. Lekárska virológia. 1. vyd. Bratislava: VEDA vydavateľstvo Slovenskej akadémie vied, 2006, 574 s. ISBN 8022409111. info
ROSYPAL, Stanislav. Úvod do molekulární biologie. Třetí inovované vydání. Brno, 2000, 300 pp. Díl III. Molekulární biologie virů. ISBN 80-902562-2-8. URL info

Teaching methods

Powerpoint presentation (slide projection) accompanied by showing of illustrations, schemes, photos and video projection. Students are continuously informed with "News in the field of Virology".

Assessment methods

Final evaluation is based on written test (Success rate 60%).

Language of instruction

Czech

Follow-Up Courses

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Listed among pre-requisites of other courses

Bi5420 General virology

Faculty of Science
Spring 2021

Extent and Intensity

2/0/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).

Teacher(s)

prof. RNDr. Ivo Rudolf, Ph.D. (lecturer)

Guaranteed by

Timetable

Mon 1. 3. to Fri 14. 5. Thu 9:00–10:50 online_B2

Prerequisites

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 9 fields of study the course is directly associated with, display

Course objectives

Learning outcomes

Syllabus

Introduction to general virology; specific terms in virology; history of virology; basic characteristic of viral particles (morphology and structure of viruses, enveloped and non-enveloped viruses); chemical composition of viruses (nucleic acids, proteins, other components of viral particles); stability of viruses in environment and inactivation of viruses (effect of temperature, pH, chemical reagents, radiation); strategy of replication of viral genome - on basis of nucleic acid type (dsDNA, ssDNA, dsRNA, +ssRNA; -ssRNA, +ssRNA-RT, dsDNA-RT); bacteriophages (lytic and lysogenic cycle); virophages; cyanophages; plant viruses; viroids; viruses of invertebrates; pathogenesis of viral diseases (definition of terms: disease, virulence, viraemia, persistent and latent infection); typical modes of virus spread in host organism including subsequent excretion of viruses from host; viral diseases of animals; imported viral infections; oncoviruses; host response to viral infection (nonspecific and specific immunity); immunization against viral diseases (active and passive approach); basic principles of vaccination; composition and types of vaccines; vaccination strategy; chemotherapy of viral diseases; direct and indirect diagnostics of viruses in clinical virology; surveillance of viral diseases; safety measures in virological laboratory; good laboratory praxis - handling with viruses; viruses and biotechnology; classification and nomenclature of viruses - characteristic of particular virus families with emphasis on medically important agents; prions and prion ´s diseases.

Literature

recommended literature

King, A.M.Q., Lefkowitz, E., Adams, M. J., Carstens, E. B. (2011). Virus Taxonomy: Ninth Report of the International Comittee on Taxonomy of Viruses, 1338 p.
COLLIER, L. H., Paul KELLAM and J. S. OXFORD. Human virology. 4th ed. Oxford: Oxford University Press, 2011, xiv, 365. ISBN 9780199570881. info
HUBÁLEK, Zdeněk and Ivo RUDOLF. Microbial Zoonoses and Sapronoses. 1st ed. Dordrecht-Heidelberg-London-New York: Springer, 2011, 457 pp. ISBN 978-90-481-9656-2. Available from: https://dx.doi.org/10.1007/978-90-481-9657-9. URL info

not specified

CARTER, John B. and Venetia A. SAUNDERS. Virology : principles and applications. 2nd ed. Chichester: Wiley, 2013, xxix, 364. ISBN 9781119991434. info
NORKIN, Leonard C. Virology : molecular biology and pathogenesis. Washington, D.C.: ASM Press, 2010, xxiii, 725. ISBN 9781555814533. info
MAHY, B. W. J. A dictionary of virology. 4th ed. Amsterdam: Elsevier, 2009, 510 s. ISBN 9780123737328. info
FLINT, S. Jane. Principles of virology. 3rd ed. Washington, DC: ASM Press, 2009, xx, 419. ISBN 9781555814809. info
RAJČÁNI, Július and Fedor ČIAMPOR. Lekárska virológia. 1. vyd. Bratislava: VEDA vydavateľstvo Slovenskej akadémie vied, 2006, 574 s. ISBN 8022409111. info
ROSYPAL, Stanislav. Úvod do molekulární biologie. Třetí inovované vydání. Brno, 2000, 300 pp. Díl III. Molekulární biologie virů. ISBN 80-902562-2-8. URL info

Teaching methods

Powerpoint presentation (slide projection) accompanied by showing of illustrations, schemes, photos and video projection. Students are continuously informed with "News in the field of Virology".

Assessment methods

Final evaluation is based on written test (Success rate 60%).

Language of instruction

Czech

Follow-Up Courses

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Listed among pre-requisites of other courses

Bi5420 General virology

Faculty of Science
Spring 2020

Extent and Intensity

2/0/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).

Teacher(s)

prof. RNDr. Ivo Rudolf, Ph.D. (lecturer)

Guaranteed by

Timetable

Thu 8:00–9:50 B11/335

Prerequisites

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 8 fields of study the course is directly associated with, display

Course objectives

Learning outcomes

Syllabus

Introduction to general virology; specific terms in virology; history of virology; basic characteristic of viral particles (morphology and structure of viruses, enveloped and non-enveloped viruses); chemical composition of viruses (nucleic acids, proteins, other components of viral particles); stability of viruses in environment and inactivation of viruses (effect of temperature, pH, chemical reagents, radiation); strategy of replication of viral genome - on basis of nucleic acid type (dsDNA, ssDNA, dsRNA, +ssRNA; -ssRNA, +ssRNA-RT, dsDNA-RT); bacteriophages (lytic and lysogenic cycle); virophages; cyanophages; plant viruses; viroids; viruses of invertebrates; pathogenesis of viral diseases (definition of terms: disease, virulence, viraemia, persistent and latent infection); typical modes of virus spread in host organism including subsequent excretion of viruses from host; viral diseases of animals; imported viral infections; oncoviruses; host response to viral infection (nonspecific and specific immunity); immunization against viral diseases (active and passive approach); basic principles of vaccination; composition and types of vaccines; vaccination strategy; chemotherapy of viral diseases; direct and indirect diagnostics of viruses in clinical virology; surveillance of viral diseases; safety measures in virological laboratory; good laboratory praxis - handling with viruses; viruses and biotechnology; classification and nomenclature of viruses - characteristic of particular virus families with emphasis on medically important agents; prions and prion ´s diseases.

Literature

recommended literature

King, A.M.Q., Lefkowitz, E., Adams, M. J., Carstens, E. B. (2011). Virus Taxonomy: Ninth Report of the International Comittee on Taxonomy of Viruses, 1338 p.
COLLIER, L. H., Paul KELLAM and J. S. OXFORD. Human virology. 4th ed. Oxford: Oxford University Press, 2011, xiv, 365. ISBN 9780199570881. info
HUBÁLEK, Zdeněk and Ivo RUDOLF. Microbial Zoonoses and Sapronoses. 1st ed. Dordrecht-Heidelberg-London-New York: Springer, 2011, 457 pp. ISBN 978-90-481-9656-2. Available from: https://dx.doi.org/10.1007/978-90-481-9657-9. URL info

not specified

CARTER, John B. and Venetia A. SAUNDERS. Virology : principles and applications. 2nd ed. Chichester: Wiley, 2013, xxix, 364. ISBN 9781119991434. info
NORKIN, Leonard C. Virology : molecular biology and pathogenesis. Washington, D.C.: ASM Press, 2010, xxiii, 725. ISBN 9781555814533. info
MAHY, B. W. J. A dictionary of virology. 4th ed. Amsterdam: Elsevier, 2009, 510 s. ISBN 9780123737328. info
FLINT, S. Jane. Principles of virology. 3rd ed. Washington, DC: ASM Press, 2009, xx, 419. ISBN 9781555814809. info
RAJČÁNI, Július and Fedor ČIAMPOR. Lekárska virológia. 1. vyd. Bratislava: VEDA vydavateľstvo Slovenskej akadémie vied, 2006, 574 s. ISBN 8022409111. info
ROSYPAL, Stanislav. Úvod do molekulární biologie. Třetí inovované vydání. Brno, 2000, 300 pp. Díl III. Molekulární biologie virů. ISBN 80-902562-2-8. URL info

Teaching methods

Powerpoint presentation (slide projection) accompanied by showing of illustrations, schemes, photos and video projection. Students are continuously informed with "News in the field of Virology".

Assessment methods

Final evaluation is based on written test (Success rate 60%).

Language of instruction

Czech

Follow-Up Courses

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Listed among pre-requisites of other courses

The course is also listed under the following terms Autumn 2002, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.

Bi5420 General virology

Faculty of Science
Spring 2019

Extent and Intensity

2/0/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).

Teacher(s)

prof. RNDr. Ivo Rudolf, Ph.D. (lecturer)

Guaranteed by

prof. RNDr. Jan Šmarda, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Ivo Rudolf, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science

Timetable

Mon 18. 2. to Fri 17. 5. Thu 8:00–9:50 B11/335

Prerequisites

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

Molecular Biology and Genetics (programme PřF, B-EXB)
Special Biology (programme PřF, B-EXB)
Special Biology (programme PřF, B-EXB, specialization Mikrobiology a Molecular Biotechnology)

Course objectives

At the end of the course, participant should repeat, translate and apply general terms operating in virology, describe basic structure of viruses, define and translate strategy of replication of viral genome and interpret current taxonomy of viruses. Participant of the course should also characterize important viral diseases of plants, invertebrates and vertebrates including humans and interpret state of the art methods and diagnostic tools used in virology. Participant will employ acquired skills in basic and applied research in virology or in diagnostic laboratories.

Syllabus

Introduction to general virology; specific terms in virology; history of virology; basic characteristic of viral particles (morphology and structure of viruses, enveloped and non-enveloped viruses); chemical composition of viruses (nucleic acids, proteins, other components of viral particles); stability of viruses in environment and inactivation of viruses (effect of temperature, pH, chemical reagents, radiation); strategy of replication of viral genome - on basis of nucleic acid type (dsDNA, ssDNA, dsRNA, +ssRNA; -ssRNA, +ssRNA-RT, dsDNA-RT); bacteriophages (lytic and lysogenic cycle); virophages; cyanophages; plant viruses; viroids; viruses of invertebrates; pathogenesis of viral diseases (definition of terms: disease, virulence, viraemia, persistent and latent infection); typical modes of virus spread in host organism including subsequent excretion of viruses from host; viral diseases of animals; imported viral infections; oncoviruses; host response to viral infection (nonspecific and specific immunity); immunization against viral diseases (active and passive approach); basic principles of vaccination; composition and types of vaccines; vaccination strategy; chemotherapy of viral diseases; direct and indirect diagnostics of viruses in clinical virology; surveillance of viral diseases; safety measures in virological laboratory; good laboratory praxis - handling with viruses; viruses and biotechnology; classification and nomenclature of viruses - characteristic of particular virus families with emphasis on medically important agents; prions and prion ´s diseases.

Literature

recommended literature

King, A.M.Q., Lefkowitz, E., Adams, M. J., Carstens, E. B. (2011). Virus Taxonomy: Ninth Report of the International Comittee on Taxonomy of Viruses, 1338 p.
COLLIER, L. H., Paul KELLAM and J. S. OXFORD. Human virology. 4th ed. Oxford: Oxford University Press, 2011, xiv, 365. ISBN 9780199570881. info
HUBÁLEK, Zdeněk and Ivo RUDOLF. Microbial Zoonoses and Sapronoses. 1st ed. Dordrecht-Heidelberg-London-New York: Springer, 2011, 457 pp. ISBN 978-90-481-9656-2. Available from: https://dx.doi.org/10.1007/978-90-481-9657-9. URL info

not specified

CARTER, John B. and Venetia A. SAUNDERS. Virology : principles and applications. 2nd ed. Chichester: Wiley, 2013, xxix, 364. ISBN 9781119991434. info
NORKIN, Leonard C. Virology : molecular biology and pathogenesis. Washington, D.C.: ASM Press, 2010, xxiii, 725. ISBN 9781555814533. info
MAHY, B. W. J. A dictionary of virology. 4th ed. Amsterdam: Elsevier, 2009, 510 s. ISBN 9780123737328. info
FLINT, S. Jane. Principles of virology. 3rd ed. Washington, DC: ASM Press, 2009, xx, 419. ISBN 9781555814809. info
RAJČÁNI, Július and Fedor ČIAMPOR. Lekárska virológia. 1. vyd. Bratislava: VEDA vydavateľstvo Slovenskej akadémie vied, 2006, 574 s. ISBN 8022409111. info
ROSYPAL, Stanislav. Úvod do molekulární biologie. Třetí inovované vydání. Brno, 2000, 300 pp. Díl III. Molekulární biologie virů. ISBN 80-902562-2-8. URL info

Teaching methods

Powerpoint presentation (slide projection) accompanied by showing of illustrations, schemes, photos and video projection. Students are continuously informed with "News in the field of Virology".

Assessment methods

Final evaluation is based on written test (Success rate 60%).

Language of instruction

Czech

Follow-Up Courses

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Listed among pre-requisites of other courses

The course is also listed under the following terms Autumn 2002, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.

Bi5420 General virology

Faculty of Science
spring 2018

Extent and Intensity

2/0/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).

Teacher(s)

prof. RNDr. Ivo Rudolf, Ph.D. (lecturer)

Guaranteed by

Timetable

Wed 9:00–10:50 B11/305

Prerequisites

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

Molecular Biology and Genetics (programme PřF, B-EXB)
Special Biology (programme PřF, B-EXB)
Special Biology (programme PřF, B-EXB, specialization Mikrobiology a Molecular Biotechnology)

Course objectives

Syllabus

Introduction to general virology; specific terms in virology; history of virology; basic characteristic of viral particles (morphology and structure of viruses, enveloped and non-enveloped viruses); chemical composition of viruses (nucleic acids, proteins, other components of viral particles); stability of viruses in environment and inactivation of viruses (effect of temperature, pH, chemical reagents, radiation); strategy of replication of viral genome - on basis of nucleic acid type (dsDNA, ssDNA, dsRNA, +ssRNA; -ssRNA, +ssRNA-RT, dsDNA-RT); bacteriophages (lytic and lysogenic cycle); virophages; cyanophages; plant viruses; viroids; viruses of invertebrates; pathogenesis of viral diseases (definition of terms: disease, virulence, viraemia, persistent and latent infection); typical modes of virus spread in host organism including subsequent excretion of viruses from host; viral diseases of animals; imported viral infections; oncoviruses; host response to viral infection (nonspecific and specific immunity); immunization against viral diseases (active and passive approach); basic principles of vaccination; composition and types of vaccines; vaccination strategy; chemotherapy of viral diseases; direct and indirect diagnostics of viruses in clinical virology; surveillance of viral diseases; safety measures in virological laboratory; good laboratory praxis - handling with viruses; viruses and biotechnology; classification and nomenclature of viruses - characteristic of particular virus families with emphasis on medically important agents; prions and prion ´s diseases.

Literature

recommended literature

King, A.M.Q., Lefkowitz, E., Adams, M. J., Carstens, E. B. (2011). Virus Taxonomy: Ninth Report of the International Comittee on Taxonomy of Viruses, 1338 p.
COLLIER, L. H., Paul KELLAM and J. S. OXFORD. Human virology. 4th ed. Oxford: Oxford University Press, 2011, xiv, 365. ISBN 9780199570881. info
HUBÁLEK, Zdeněk and Ivo RUDOLF. Microbial Zoonoses and Sapronoses. 1st ed. Dordrecht-Heidelberg-London-New York: Springer, 2011, 457 pp. ISBN 978-90-481-9656-2. Available from: https://dx.doi.org/10.1007/978-90-481-9657-9. URL info

not specified

CARTER, John B. and Venetia A. SAUNDERS. Virology : principles and applications. 2nd ed. Chichester: Wiley, 2013, xxix, 364. ISBN 9781119991434. info
NORKIN, Leonard C. Virology : molecular biology and pathogenesis. Washington, D.C.: ASM Press, 2010, xxiii, 725. ISBN 9781555814533. info
MAHY, B. W. J. A dictionary of virology. 4th ed. Amsterdam: Elsevier, 2009, 510 s. ISBN 9780123737328. info
FLINT, S. Jane. Principles of virology. 3rd ed. Washington, DC: ASM Press, 2009, xx, 419. ISBN 9781555814809. info
RAJČÁNI, Július and Fedor ČIAMPOR. Lekárska virológia. 1. vyd. Bratislava: VEDA vydavateľstvo Slovenskej akadémie vied, 2006, 574 s. ISBN 8022409111. info
ROSYPAL, Stanislav. Úvod do molekulární biologie. Třetí inovované vydání. Brno, 2000, 300 pp. Díl III. Molekulární biologie virů. ISBN 80-902562-2-8. URL info

Teaching methods

Powerpoint presentation (slide projection) accompanied by showing of illustrations, schemes, photos and video projection. Students are continuously informed with "News in the field of Virology".

Assessment methods

Final evaluation is based on written test (Success rate 60%).

Language of instruction

Czech

Follow-Up Courses

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Listed among pre-requisites of other courses

The course is also listed under the following terms Autumn 2002, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.

Bi5420 General virology

Faculty of Science
Spring 2017

Extent and Intensity

2/0/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).

Teacher(s)

prof. RNDr. Ivo Rudolf, Ph.D. (lecturer)

Guaranteed by

Timetable

Mon 20. 2. to Mon 22. 5. Thu 12:00–13:50 B11/235

Prerequisites

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

Molecular Biology and Genetics (programme PřF, B-EXB)
Special Biology (programme PřF, B-EXB)
Special Biology (programme PřF, B-EXB, specialization Mikrobiology a Molecular Biotechnology)

Course objectives

Syllabus

Introduction to general virology; specific terms in virology; history of virology; basic characteristic of viral particles (morphology and structure of viruses, enveloped and non-enveloped viruses); chemical composition of viruses (nucleic acids, proteins, other components of viral particles); stability of viruses in environment and inactivation of viruses (effect of temperature, pH, chemical reagents, radiation); strategy of replication of viral genome - on basis of nucleic acid type (dsDNA, ssDNA, dsRNA, +ssRNA; -ssRNA, +ssRNA-RT, dsDNA-RT); bacteriophages (lytic and lysogenic cycle); virophages; cyanophages; plant viruses; viroids; viruses of invertebrates; pathogenesis of viral diseases (definition of terms: disease, virulence, viraemia, persistent and latent infection); typical modes of virus spread in host organism including subsequent excretion of viruses from host; viral diseases of animals; imported viral infections; oncoviruses; host response to viral infection (nonspecific and specific immunity); immunization against viral diseases (active and passive approach); basic principles of vaccination; composition and types of vaccines; vaccination strategy; chemotherapy of viral diseases; direct and indirect diagnostics of viruses in clinical virology; surveillance of viral diseases; safety measures in virological laboratory; good laboratory praxis - handling with viruses; viruses and biotechnology; classification and nomenclature of viruses - characteristic of particular virus families with emphasis on medically important agents; prions and prion ´s diseases.

Literature

recommended literature

King, A.M.Q., Lefkowitz, E., Adams, M. J., Carstens, E. B. (2011). Virus Taxonomy: Ninth Report of the International Comittee on Taxonomy of Viruses, 1338 p.
COLLIER, L. H., Paul KELLAM and J. S. OXFORD. Human virology. 4th ed. Oxford: Oxford University Press, 2011, xiv, 365. ISBN 9780199570881. info
HUBÁLEK, Zdeněk and Ivo RUDOLF. Microbial Zoonoses and Sapronoses. 1st ed. Dordrecht-Heidelberg-London-New York: Springer, 2011, 457 pp. ISBN 978-90-481-9656-2. Available from: https://dx.doi.org/10.1007/978-90-481-9657-9. URL info

not specified

CARTER, John B. and Venetia A. SAUNDERS. Virology : principles and applications. 2nd ed. Chichester: Wiley, 2013, xxix, 364. ISBN 9781119991434. info
NORKIN, Leonard C. Virology : molecular biology and pathogenesis. Washington, D.C.: ASM Press, 2010, xxiii, 725. ISBN 9781555814533. info
MAHY, B. W. J. A dictionary of virology. 4th ed. Amsterdam: Elsevier, 2009, 510 s. ISBN 9780123737328. info
FLINT, S. Jane. Principles of virology. 3rd ed. Washington, DC: ASM Press, 2009, xx, 419. ISBN 9781555814809. info
RAJČÁNI, Július and Fedor ČIAMPOR. Lekárska virológia. 1. vyd. Bratislava: VEDA vydavateľstvo Slovenskej akadémie vied, 2006, 574 s. ISBN 8022409111. info
ROSYPAL, Stanislav. Úvod do molekulární biologie. Třetí inovované vydání. Brno, 2000, 300 pp. Díl III. Molekulární biologie virů. ISBN 80-902562-2-8. URL info

Teaching methods

Powerpoint presentation (slide projection) accompanied by showing of illustrations, schemes, photos and video projection. Students are continuously informed with "News in the field of Virology".

Assessment methods

Final evaluation is based on written test (Success rate 60%).

Language of instruction

Czech

Follow-Up Courses

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Listed among pre-requisites of other courses

The course is also listed under the following terms Autumn 2002, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Spring 2013, Spring 2014, Spring 2015, Spring 2016, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.

Bi5420 General virology

Faculty of Science
Spring 2016

Extent and Intensity

2/0/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).

Teacher(s)

prof. RNDr. Ivo Rudolf, Ph.D. (lecturer)

Guaranteed by

Timetable

Thu 12:00–13:50 B11/235

Prerequisites

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

Molecular Biology and Genetics (programme PřF, B-EXB)
Special Biology (programme PřF, B-EXB)
Special Biology (programme PřF, B-EXB, specialization Mikrobiology a Molecular Biotechnology)

Course objectives

Syllabus

Introduction to general virology; specific terms in virology; history of virology; basic characteristic of viral particles (morphology and structure of viruses, enveloped and non-enveloped viruses); chemical composition of viruses (nucleic acids, proteins, other components of viral particles); stability of viruses in environment and inactivation of viruses (effect of temperature, pH, chemical reagents, radiation); strategy of replication of viral genome - on basis of nucleic acid type (dsDNA, ssDNA, dsRNA, +ssRNA; -ssRNA, +ssRNA-RT, dsDNA-RT); bacteriophages (lytic and lysogenic cycle); virophages; cyanophages; plant viruses; viroids; viruses of invertebrates; pathogenesis of viral diseases (definition of terms: disease, virulence, viraemia, persistent and latent infection); typical modes of virus spread in host organism including subsequent excretion of viruses from host; viral diseases of animals; imported viral infections; oncoviruses; host response to viral infection (nonspecific and specific immunity); immunization against viral diseases (active and passive approach); basic principles of vaccination; composition and types of vaccines; vaccination strategy; chemotherapy of viral diseases; direct and indirect diagnostics of viruses in clinical virology; surveillance of viral diseases; safety measures in virological laboratory; good laboratory praxis - handling with viruses; viruses and biotechnology; classification and nomenclature of viruses - characteristic of particular virus families with emphasis on medically important agents; prions and prion ´s diseases.

Literature

recommended literature

King, A.M.Q., Lefkowitz, E., Adams, M. J., Carstens, E. B. (2011). Virus Taxonomy: Ninth Report of the International Comittee on Taxonomy of Viruses, 1338 p.
COLLIER, L. H., Paul KELLAM and J. S. OXFORD. Human virology. 4th ed. Oxford: Oxford University Press, 2011, xiv, 365. ISBN 9780199570881. info
HUBÁLEK, Zdeněk and Ivo RUDOLF. Microbial Zoonoses and Sapronoses. 1st ed. Dordrecht-Heidelberg-London-New York: Springer, 2011, 457 pp. ISBN 978-90-481-9656-2. Available from: https://dx.doi.org/10.1007/978-90-481-9657-9. URL info

not specified

CARTER, John B. and Venetia A. SAUNDERS. Virology : principles and applications. 2nd ed. Chichester: Wiley, 2013, xxix, 364. ISBN 9781119991434. info
NORKIN, Leonard C. Virology : molecular biology and pathogenesis. Washington, D.C.: ASM Press, 2010, xxiii, 725. ISBN 9781555814533. info
MAHY, B. W. J. A dictionary of virology. 4th ed. Amsterdam: Elsevier, 2009, 510 s. ISBN 9780123737328. info
FLINT, S. Jane. Principles of virology. 3rd ed. Washington, DC: ASM Press, 2009, xx, 419. ISBN 9781555814809. info
RAJČÁNI, Július and Fedor ČIAMPOR. Lekárska virológia. 1. vyd. Bratislava: VEDA vydavateľstvo Slovenskej akadémie vied, 2006, 574 s. ISBN 8022409111. info
ROSYPAL, Stanislav. Úvod do molekulární biologie. Třetí inovované vydání. Brno, 2000, 300 pp. Díl III. Molekulární biologie virů. ISBN 80-902562-2-8. URL info

Teaching methods

Powerpoint presentation (slide projection) accompanied by showing of illustrations, schemes, photos and video projection. Students are continuously informed with "News in the field of Virology".

Assessment methods

Final evaluation is based on written test (Success rate 60%).

Language of instruction

Czech

Follow-Up Courses

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Listed among pre-requisites of other courses

The course is also listed under the following terms Autumn 2002, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Spring 2013, Spring 2014, Spring 2015, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.

Bi5420 General virology

Faculty of Science
Spring 2015

Extent and Intensity

2/0/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).

Teacher(s)

prof. RNDr. Ivo Rudolf, Ph.D. (lecturer)

Guaranteed by

Timetable

Thu 12:00–13:50 B11/235

Prerequisites

( Bi4020 Molecular biology || NOW( Bi4020 Molecular biology )) && ( Bi4090 General microbiology || NOW( Bi4090 General microbiology ))
Course has been established for students of orientation Biology (specialization general biology, molecular biology and genetics, special biology) and also to other potential participants interested in virology.

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

Molecular Biology and Genetics (programme PřF, B-EXB)
Special Biology (programme PřF, B-EXB)
Special Biology (programme PřF, B-EXB, specialization Mikrobiology a Molecular Biotechnology)

Course objectives

At the end of the course, participant should repeat, translate and apply general terms operating in virology, describe basic structure of viruses, define and translate strategy of replication and expression of viral genome and interpret current taxonomy of viruses. Participant of the course should also characterize important viral diseases of plants, invertebrates and vertebrates including humans and interpret state of the art methods and diagnostic tools used in virology. Participant will employ acquired skills in basic and applied research in virology or in diagnostic laboratories.

Syllabus

Introduction to general virology; specific terms in virology; history of virology; basic characteristic of viral particles (morphology and structure of viruses, enveloped and non-enveloped viruses); chemical composition of viruses (nucleic acids, proteins, other components of viral particles); stability of viruses in environment and inactivation of viruses (effect of temperature, pH, chemical reagents, radiation); strategy of replication and expression of viral genome on basis of nucleic acid type (dsDNA, ssDNA, dsRNA, +ssRNA; -ssRNA, +ssRNA-RT, dsDNA-RT); bacteriophages (lytic and lysogenic cycle); virophages; cyanophages; plant viruses; viroids; viruses of invertebrates; pathogenesis of viral diseases of vertebrates (definition of terms: disease, virulence, viraemia, persistent infection); typical modes of virus spread in host organism including subsequent excretion of viruses from host; viral diseases of animals; imported viral infections; oncoviruses; host response to viral infection (nonspecific and specific immunity); immunization against viral diseases (active and passive); basic principles of vaccination; composition and types of vaccines; vaccination strategy; chemotherapy of viral diseases; direct and indirect diagnostics of viruses in clinical virology; surveillance of viral diseases; safety measures in virological laboratory; good laboratory praxis in handling with viruses; viruses and biotechnology; classification and nomenclature of viruses - characteristic of particular virus families with emphasis on medically important members; prions and prion ´s diseases in humans.

Literature

recommended literature

King, A.M.Q., Lefkowitz, E., Adams, M. J., Carstens, E. B. (2011). Virus Taxonomy: Ninth Report of the International Comittee on Taxonomy of Viruses, 1338 p.
COLLIER, L. H., Paul KELLAM and J. S. OXFORD. Human virology. 4th ed. Oxford: Oxford University Press, 2011, xiv, 365. ISBN 9780199570881. info
HUBÁLEK, Zdeněk and Ivo RUDOLF. Microbial Zoonoses and Sapronoses. 1st ed. Dordrecht-Heidelberg-London-New York: Springer, 2011, 457 pp. ISBN 978-90-481-9656-2. Available from: https://dx.doi.org/10.1007/978-90-481-9657-9. URL info

not specified

NORKIN, Leonard C. Virology : molecular biology and pathogenesis. Washington, D.C.: ASM Press, 2010, xxiii, 725. ISBN 9781555814533. info
MAHY, B. W. J. A dictionary of virology. 4th ed. Amsterdam: Elsevier, 2009, 510 s. ISBN 9780123737328. info
FLINT, S. Jane. Principles of virology. 3rd ed. Washington, DC: ASM Press, 2009, xx, 419. ISBN 9781555814809. info
RAJČÁNI, Július and Fedor ČIAMPOR. Lekárska virológia. 1. vyd. Bratislava: VEDA vydavateľstvo Slovenskej akadémie vied, 2006, 574 s. ISBN 8022409111. info
VOTAVA, Miroslav. Lékařská mikrobiologie speciální. 1. vyd. Brno: Neptun, 2003, xxii, 495. ISBN 80-902896-6-5. info
ROSYPAL, Stanislav. Úvod do molekulární biologie. Třetí inovované vydání. Brno, 2000, 300 pp. Díl III. Molekulární biologie virů. ISBN 80-902562-2-8. URL info

Teaching methods

Powerpoint presentation (slide projection) accompanied by showing of illustrations, schemes, photos and video projection.

Assessment methods

Final evaluation is based on written test (Success rate 60%).

Language of instruction

Czech

Follow-Up Courses

Bi7140 Molecular biology of viruses

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Listed among pre-requisites of other courses

The course is also listed under the following terms Autumn 2002, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Spring 2013, Spring 2014, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.

Bi5420 General virology

Faculty of Science
Spring 2014

Extent and Intensity

2/0/0. 4 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).

Teacher(s)

prof. RNDr. Ivo Rudolf, Ph.D. (lecturer)

Guaranteed by

Timetable

Thu 16:00–17:50 B11/235

Prerequisites

( Bi4020 Molecular biology || NOW( Bi4020 Molecular biology )) && ( Bi4090 General microbiology || NOW( Bi4090 General microbiology ))
Course has been established for students of orientation Biology (specialization general biology, molecular biology and genetics, special biology) and also to other potential participants interested in virology.

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

Molecular Biology and Genetics (programme PřF, B-EXB)
Special Biology (programme PřF, B-EXB)
Special Biology (programme PřF, B-EXB, specialization Mikrobiology a Molecular Biotechnology)

Course objectives

At the end of the course, participant should repeat, translate and apply general terms operating in virology, describe basic structure of viruses, define and translate strategy of replication and expression of viral genome and interpret current taxonomy of viruses. Participant of the course should also characterize important viral diseases of plants, invertebrates and vertebrates including humans and interpret state of the art methods and diagnostic tools used in virology. Participant will employ acquired skills in basic and applied research in virology or in diagnostic laboratories.

Syllabus

Introduction to general virology; specific terms in virology; history of virology; basic characteristic of viral particles (morphology and structure of viruses, enveloped and non-enveloped viruses); chemical composition of viruses (nucleic acids, proteins, other components of viral particles); stability of viruses in environment and inactivation of viruses (effect of temperature, pH, chemical reagents, radiation); strategy of replication and expression of viral genome on basis of nucleic acid type (dsDNA, ssDNA, dsRNA, +ssRNA; -ssRNA, +ssRNA-RT, dsDNA-RT); bacteriophages (lytic and lysogenic cycle); virophages; cyanophages; plant viruses; viroids; viruses of invertebrates; pathogenesis of viral diseases of vertebrates (definition of terms: disease, virulence, viraemia, persistent infection); typical modes of virus spread in host organism including subsequent excretion of viruses from host; viral diseases of animals; imported viral infections; oncoviruses; host response to viral infection (nonspecific and specific immunity); immunization against viral diseases (active and passive); basic principles of vaccination; composition and types of vaccines; vaccination strategy; chemotherapy of viral diseases; direct and indirect diagnostics of viruses in clinical virology; surveillance of viral diseases; safety measures in virological laboratory; good laboratory praxis in handling with viruses; viruses and biotechnology; classification and nomenclature of viruses - characteristic of particular virus families with emphasis on medically important members; prions and prion ´s diseases in humans.

Literature

recommended literature

King, A.M.Q., Lefkowitz, E., Adams, M. J., Carstens, E. B. (2011). Virus Taxonomy: Ninth Report of the International Comittee on Taxonomy of Viruses, 1338 p.
COLLIER, L. H., Paul KELLAM and J. S. OXFORD. Human virology. 4th ed. Oxford: Oxford University Press, 2011, xiv, 365. ISBN 9780199570881. info
HUBÁLEK, Zdeněk and Ivo RUDOLF. Microbial Zoonoses and Sapronoses. 1st ed. Dordrecht-Heidelberg-London-New York: Springer, 2011, 457 pp. ISBN 978-90-481-9656-2. Available from: https://dx.doi.org/10.1007/978-90-481-9657-9. URL info

not specified

NORKIN, Leonard C. Virology : molecular biology and pathogenesis. Washington, D.C.: ASM Press, 2010, xxiii, 725. ISBN 9781555814533. info
MAHY, B. W. J. A dictionary of virology. 4th ed. Amsterdam: Elsevier, 2009, 510 s. ISBN 9780123737328. info
FLINT, S. Jane. Principles of virology. 3rd ed. Washington, DC: ASM Press, 2009, xx, 419. ISBN 9781555814809. info
RAJČÁNI, Július and Fedor ČIAMPOR. Lekárska virológia. 1. vyd. Bratislava: VEDA vydavateľstvo Slovenskej akadémie vied, 2006, 574 s. ISBN 8022409111. info
VOTAVA, Miroslav. Lékařská mikrobiologie speciální. 1. vyd. Brno: Neptun, 2003, xxii, 495. ISBN 80-902896-6-5. info
ROSYPAL, Stanislav. Úvod do molekulární biologie. Třetí inovované vydání. Brno, 2000, 300 pp. Díl III. Molekulární biologie virů. ISBN 80-902562-2-8. URL info

Teaching methods

Powerpoint presentation (slide projection) accompanied by showing of illustrations, schemes, photos and video projection.

Assessment methods

Final evaluation is based on written test (Success rate 60%).

Language of instruction

Czech

Follow-Up Courses

Bi7140 Molecular biology of viruses

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Listed among pre-requisites of other courses

The course is also listed under the following terms Autumn 2002, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Spring 2013, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.

Bi5420 General virology

Faculty of Science
Spring 2013

Extent and Intensity

2/0/0. 4 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

prof. RNDr. Ivo Rudolf, Ph.D. (lecturer)
Mgr. et Mgr. Veronika Oškerová, Ph.D. (assistant)

Guaranteed by

Timetable

Thu 16:00–17:50 B11/235

Prerequisites

( Bi4020 Molecular biology || NOW( Bi4020 Molecular biology )) && ( Bi4090 General microbiology || NOW( Bi4090 General microbiology ))
Course has been established for students of orientation Biology (specialization general biology, molecular biology and genetics, special biology) and also to other potential participants interested in virology.

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

Molecular Biology and Genetics (programme PřF, B-EXB)
Special Biology (programme PřF, B-EXB)
Special Biology (programme PřF, B-EXB, specialization Mikrobiology a Molecular Biotechnology)

Course objectives

At the end of the course, participant should repeat, translate and apply general terms operating in general virology, distinguish different basic structure of viruses, define and translate strategy of replication and expression of viral genome and interpret current taxonomy of viruses. Participant of the course should also characterize important viral diseases of plants, invertebrates and vertebrates including humans and interpretate state of the art methods and diagnostic tools used in virology. Participant will employ acquired skills in basic and applied research in virology or in diagnostic laboratories.

Syllabus

Introduction to general virology; specific terms in virology; history of virology; basic characteristic of viral particles (morphology and structure of viruses, enveloped and non-enveloped viruses); chemical composition of viruses (nucleic acids, proteins, other components of viral particles); stability of viruses in environment and inactivation of viruses (effect of temperature, pH, chemical reagents, radiation); strategy of replication and expression of viral genome on basis of nucleic acid type (dsDNA, ssDNA, dsRNA, +ssRNA; -ssRNA, +ssRNA-RT, dsDNA-RT); bacteriophages (lytic and lysogenic cycle); virophages; cyanophages; plant viruses; viroids; viruses of invertebrates; pathogenesis of viral diseases of vertebrates (definition of terms: disease, virulence, viraemia, persistent infection); typical modes of virus spread in host organism including subsequent excretion of viruses from host; viral diseases of animals; imported viral infections; oncoviruses; host response to viral infection (nonspecific and specific immunity); immunization against viral diseases (active and passive); basic principles of vaccination; composition and types of vaccines; vaccination strategy; chemotherapy of viral diseases; direct and indirect diagnostics of viruses in clinical virology; surveillance of viral diseases; safety measures in virological laboratory; good laboratory praxis in handling with viruses; viruses and biotechnology; classification and nomenclature of viruses - characteristic of particular virus families with emphasis on medically important members; prions and prion ´s diseases in humans.

Literature

recommended literature

King, A.M.Q., Lefkowitz, E., Adams, M. J., Carstens, E. B. (2011). Virus Taxonomy: Ninth Report of the International Comittee on Taxonomy of Viruses, 1338 p.
COLLIER, L. H., Paul KELLAM and J. S. OXFORD. Human virology. 4th ed. Oxford: Oxford University Press, 2011, xiv, 365. ISBN 9780199570881. info
HUBÁLEK, Zdeněk and Ivo RUDOLF. Microbial Zoonoses and Sapronoses. 1st ed. Dordrecht-Heidelberg-London-New York: Springer, 2011, 457 pp. ISBN 978-90-481-9656-2. Available from: https://dx.doi.org/10.1007/978-90-481-9657-9. URL info

not specified

NORKIN, Leonard C. Virology : molecular biology and pathogenesis. Washington, D.C.: ASM Press, 2010, xxiii, 725. ISBN 9781555814533. info
MAHY, B. W. J. A dictionary of virology. 4th ed. Amsterdam: Elsevier, 2009, 510 s. ISBN 9780123737328. info
FLINT, S. Jane. Principles of virology. 3rd ed. Washington, DC: ASM Press, 2009, xx, 419. ISBN 9781555814809. info
RAJČÁNI, Július and Fedor ČIAMPOR. Lekárska virológia. 1. vyd. Bratislava: VEDA vydavateľstvo Slovenskej akadémie vied, 2006, 574 s. ISBN 8022409111. info
VOTAVA, Miroslav. Lékařská mikrobiologie speciální. 1. vyd. Brno: Neptun, 2003, xxii, 495. ISBN 80-902896-6-5. info
ROSYPAL, Stanislav. Úvod do molekulární biologie. Třetí inovované vydání. Brno, 2000, 300 pp. Díl III. Molekulární biologie virů. ISBN 80-902562-2-8. URL info
Špeciálna virológia. Edited by Jaroslav Žemla - Fedor Čiampor - Milan Labuda. 1. vyd. Bratislava: Slovac Academic Press, 1998, 226 s., č. ISBN 80-88908-04-3. info
Všeobecná virológia. Edited by Jaroslav Žemla - Fedor Čiampor - Jozef Leššo. 1. vyd. Bratislava: Slovac Academic Press, 1995, 238 s., il. ISBN 80-85665-47-6. info

Teaching methods

Powerpoint presentation (slide projection) accompanied by showing of illustrations, schemes, photos and video projection.

Assessment methods

Final evaluation is based on written test (Success rate 60%).

Language of instruction

Czech

Follow-Up Courses

Bi7140 Molecular biology of viruses

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Listed among pre-requisites of other courses

The course is also listed under the following terms Autumn 2002, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.

Bi5420 General virology

Faculty of Science
Autumn 2006

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

RNDr. Danuška Horáková, CSc. (lecturer)
doc. Mgr. Monika Vítězová, Ph.D. (lecturer)

Guaranteed by

RNDr. Danuška Horáková, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Danuška Horáková, CSc.

Timetable

Tue 8:00–9:50 Bpt,01013

Prerequisites (in Czech)

Přednáška je určena studujícím obecné biologie a dalším zájemcům o obor virologie. Předpokladem pro zápis tohoto předmětu je složení zkoušek z obecné biologie, z obecné mikrobiologie

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

Cellular and Molecular Diagnostics (programme PřF, B-BI)
General Biology (programme PřF, B-BI, specialization Microbiology)

Course objectives

Introduction. Structure of viruses - morphology and chemical composition of viruses, inactivation of viruses. Classification of viruses - criteria of classificationanimal viruses, plant viruses,insect viruses, bacteriophages. Methods of investigations of viruses, cultivation and assay of viruses. The viral multiplication cycle - adsorption, penetration, transcription, translation, replication of viral nucleic acid, morphogenesis. Reproduction of animal viruses. Reproduction of plant viruses. Reproduction of bacteriophages. Viral genetics - mutation, abortive infections and defective viruses, genetic interaction between viruses, interactions between viral gene products, the genetic basis of virulence. Pathogenesis of viral infections - pathogenicity and virulence, routes of entry, mechanisms of spread in the organismus, virus shedding. Host responses to viral infections, antiviral immunological mechanisms, immunization. Chemotherapy of viral diseases - nucleoside analogs, other antiviral agents, strategy for development of antiviral agents. Epidemiology and control of viral infections. Laboratory diagnosis of viral diseases. Viral diseases (assortment).Viruses and biotechnology;

Syllabus

Introduction. Structure of viruses - morphology and chemical composition of viruses, inactivation of viruses. Classification of viruses - criteria of classificationanimal viruses, plant viruses,insect viruses, bacteriophages. Methods of investigations of viruses, cultivation and assay of viruses. The viral multiplication cycle - adsorption, penetration, transcription, translation, replication of viral nucleic acid, morphogenesis. Reproduction of animal viruses. Reproduction of plant viruses. Reproduction of bacteriophages. Viral genetics - mutation, abortive infections and defective viruses, genetic interaction between viruses, interactions between viral gene products, the genetic basis of virulence. Pathogenesis of viral infections - pathogenicity and virulence, routes of entry, mechanisms of spread in the organismus, virus shedding. Host responses to viral infections, antiviral immunological mechanisms, immunization. Chemotherapy of viral diseases - nucleoside analogs, other antiviral agents, strategy for development of antiviral agents. Epidemiology and control of viral infections. Laboratory diagnosis of viral diseases. Viral diseases (assortment).Viruses and biotechnology;

Literature

TIMBURY, Morag C. Notes on medical virology. 11th ed. New York: Churchill Livingstone, 1997, 196 s. ISBN 0-443-05846-6. info
BEDNÁŘ, Marek. Lékařská mikrobiologie : bakteriologie, virologie, parazitologie. 1. vyd. Praha: Marvil, 1996, 558 s. info
ROSYPAL, Stanislav. Bakteriologie a virologie. 1. vyd. Praha: Scientia, 1994, 67 s. ISBN 80-85827-16-6. info
LEVY, Jay A., Heinz FRAENKEL-CONRAT and Robert A. OWENS. Virology. 3rd ed. Englewood Cliffs: Prentice-Hall, 1994, xii, 447 s. ISBN 0-13-953753-8. info
CANN, Alan J. Principles of molecular virology. London: Academic Press, 1993, 234 s. ISBN 0-12-158531-X. info

Assessment methods (in Czech)

Přednáška.Zkouška ústní.

Language of instruction

Czech

Further comments (probably available only in Czech)

The course is taught annually.

Listed among pre-requisites of other courses

The course is also listed under the following terms Autumn 2002, Autumn 2003, Autumn 2004, Autumn 2005, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.

Bi5420 General virology

Faculty of Science
Autumn 2005

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

RNDr. Danuška Horáková, CSc. (lecturer)
doc. Mgr. Monika Vítězová, Ph.D. (lecturer)

Guaranteed by

RNDr. Danuška Horáková, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Danuška Horáková, CSc.

Timetable

Mon 12:00–13:50 Bpt,01013

Prerequisites (in Czech)

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

Cellular and Molecular Diagnostics (programme PřF, B-BI)
General Biology (programme PřF, B-BI, specialization Microbiology)

Course objectives

Syllabus

Introduction. Structure of viruses - morphology and chemical composition of viruses, inactivation of viruses. Classification of viruses - criteria of classificationanimal viruses, plant viruses,insect viruses, bacteriophages. Methods of investigations of viruses, cultivation and assay of viruses. The viral multiplication cycle - adsorption, penetration, transcription, translation, replication of viral nucleic acid, morphogenesis. Reproduction of animal viruses. Reproduction of plant viruses. Reproduction of bacteriophages. Viral genetics - mutation, abortive infections and defective viruses, genetic interaction between viruses, interactions between viral gene products, the genetic basis of virulence. Pathogenesis of viral infections - pathogenicity and virulence, routes of entry, mechanisms of spread in the organismus, virus shedding. Host responses to viral infections, antiviral immunological mechanisms, immunization. Chemotherapy of viral diseases - nucleoside analogs, other antiviral agents, strategy for development of antiviral agents. Epidemiology and control of viral infections. Laboratory diagnosis of viral diseases. Viral diseases (assortment).Viruses and biotechnology;

Literature

TIMBURY, Morag C. Notes on medical virology. 11th ed. New York: Churchill Livingstone, 1997, 196 s. ISBN 0-443-05846-6. info
BEDNÁŘ, Marek. Lékařská mikrobiologie : bakteriologie, virologie, parazitologie. 1. vyd. Praha: Marvil, 1996, 558 s. info
ROSYPAL, Stanislav. Bakteriologie a virologie. 1. vyd. Praha: Scientia, 1994, 67 s. ISBN 80-85827-16-6. info
LEVY, Jay A., Heinz FRAENKEL-CONRAT and Robert A. OWENS. Virology. 3rd ed. Englewood Cliffs: Prentice-Hall, 1994, xii, 447 s. ISBN 0-13-953753-8. info
CANN, Alan J. Principles of molecular virology. London: Academic Press, 1993, 234 s. ISBN 0-12-158531-X. info

Assessment methods (in Czech)

Přednáška.Zkouška ústní.

Language of instruction

Czech

Further comments (probably available only in Czech)

The course is taught annually.

Listed among pre-requisites of other courses

The course is also listed under the following terms Autumn 2002, Autumn 2003, Autumn 2004, Autumn 2006, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.

Bi5420 General virology

Faculty of Science
Autumn 2004

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

RNDr. Danuška Horáková, CSc. (lecturer)

Guaranteed by

RNDr. Danuška Horáková, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Danuška Horáková, CSc.

Timetable

Mon 16:00–17:50 B1,01004

Prerequisites (in Czech)

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

Cellular and Molecular Diagnostics (programme PřF, B-BI)
General Biology (programme PřF, B-BI, specialization Microbiology)

Course objectives

Syllabus

Introduction. Structure of viruses - morphology and chemical composition of viruses, inactivation of viruses. Classification of viruses - criteria of classificationanimal viruses, plant viruses,insect viruses, bacteriophages. Methods of investigations of viruses, cultivation and assay of viruses. The viral multiplication cycle - adsorption, penetration, transcription, translation, replication of viral nucleic acid, morphogenesis. Reproduction of animal viruses. Reproduction of plant viruses. Reproduction of bacteriophages. Viral genetics - mutation, abortive infections and defective viruses, genetic interaction between viruses, interactions between viral gene products, the genetic basis of virulence. Pathogenesis of viral infections - pathogenicity and virulence, routes of entry, mechanisms of spread in the organismus, virus shedding. Host responses to viral infections, antiviral immunological mechanisms, immunization. Chemotherapy of viral diseases - nucleoside analogs, other antiviral agents, strategy for development of antiviral agents. Epidemiology and control of viral infections. Laboratory diagnosis of viral diseases. Viral diseases (assortment).Viruses and biotechnology;

Literature

TIMBURY, Morag C. Notes on medical virology. 11th ed. New York: Churchill Livingstone, 1997, 196 s. ISBN 0-443-05846-6. info
BEDNÁŘ, Marek. Lékařská mikrobiologie : bakteriologie, virologie, parazitologie. 1. vyd. Praha: Marvil, 1996, 558 s. info
ROSYPAL, Stanislav. Bakteriologie a virologie. 1. vyd. Praha: Scientia, 1994, 67 s. ISBN 80-85827-16-6. info
LEVY, Jay A., Heinz FRAENKEL-CONRAT and Robert A. OWENS. Virology. 3rd ed. Englewood Cliffs: Prentice-Hall, 1994, xii, 447 s. ISBN 0-13-953753-8. info
CANN, Alan J. Principles of molecular virology. London: Academic Press, 1993, 234 s. ISBN 0-12-158531-X. info

Assessment methods (in Czech)

Přednáška.Zkouška ústní.

Language of instruction

Czech

Further comments (probably available only in Czech)

The course is taught annually.

Listed among pre-requisites of other courses

The course is also listed under the following terms Autumn 2002, Autumn 2003, Autumn 2005, Autumn 2006, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.

Bi5420 General virology

Faculty of Science
Autumn 2003

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

RNDr. Danuška Horáková, CSc. (lecturer)

Guaranteed by

RNDr. Danuška Horáková, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Danuška Horáková, CSc.

Prerequisites (in Czech)

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

Cellular and Molecular Diagnostics (programme PřF, B-BI)
General Biology (programme PřF, B-BI, specialization Microbiology)

Course objectives

Syllabus

Introduction. Structure of viruses - morphology and chemical composition of viruses, inactivation of viruses. Classification of viruses - criteria of classificationanimal viruses, plant viruses,insect viruses, bacteriophages. Methods of investigations of viruses, cultivation and assay of viruses. The viral multiplication cycle - adsorption, penetration, transcription, translation, replication of viral nucleic acid, morphogenesis. Reproduction of animal viruses. Reproduction of plant viruses. Reproduction of bacteriophages. Viral genetics - mutation, abortive infections and defective viruses, genetic interaction between viruses, interactions between viral gene products, the genetic basis of virulence. Pathogenesis of viral infections - pathogenicity and virulence, routes of entry, mechanisms of spread in the organismus, virus shedding. Host responses to viral infections, antiviral immunological mechanisms, immunization. Chemotherapy of viral diseases - nucleoside analogs, other antiviral agents, strategy for development of antiviral agents. Epidemiology and control of viral infections. Laboratory diagnosis of viral diseases. Viral diseases (assortment).Viruses and biotechnology;

Literature

TIMBURY, Morag C. Notes on medical virology. 11th ed. New York: Churchill Livingstone, 1997, 196 s. ISBN 0-443-05846-6. info
BEDNÁŘ, Marek. Lékařská mikrobiologie : bakteriologie, virologie, parazitologie. 1. vyd. Praha: Marvil, 1996, 558 s. info
ROSYPAL, Stanislav. Bakteriologie a virologie. 1. vyd. Praha: Scientia, 1994, 67 s. ISBN 80-85827-16-6. info
LEVY, Jay A., Heinz FRAENKEL-CONRAT and Robert A. OWENS. Virology. 3rd ed. Englewood Cliffs: Prentice-Hall, 1994, xii, 447 s. ISBN 0-13-953753-8. info
CANN, Alan J. Principles of molecular virology. London: Academic Press, 1993, 234 s. ISBN 0-12-158531-X. info

Assessment methods (in Czech)

Přednáška.Zkouška ústní.

Language of instruction

Czech

Further comments (probably available only in Czech)

The course is taught annually.
The course is taught: every week.

Listed among pre-requisites of other courses

The course is also listed under the following terms Autumn 2002, Autumn 2004, Autumn 2005, Autumn 2006, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.

Bi5420 General virology

Faculty of Science
Autumn 2002

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

RNDr. Danuška Horáková, CSc. (lecturer)

Guaranteed by

RNDr. Danuška Horáková, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Danuška Horáková, CSc.

Prerequisites (in Czech)

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

General Biology (programme PřF, B-BI, specialization Microbiology)

Course objectives

Syllabus

Introduction. Structure of viruses - morphology and chemical composition of viruses, inactivation of viruses. Classification of viruses - criteria of classificationanimal viruses, plant viruses,insect viruses, bacteriophages. Methods of investigations of viruses, cultivation and assay of viruses. The viral multiplication cycle - adsorption, penetration, transcription, translation, replication of viral nucleic acid, morphogenesis. Reproduction of animal viruses. Reproduction of plant viruses. Reproduction of bacteriophages. Viral genetics - mutation, abortive infections and defective viruses, genetic interaction between viruses, interactions between viral gene products, the genetic basis of virulence. Pathogenesis of viral infections - pathogenicity and virulence, routes of entry, mechanisms of spread in the organismus, virus shedding. Host responses to viral infections, antiviral immunological mechanisms, immunization. Chemotherapy of viral diseases - nucleoside analogs, other antiviral agents, strategy for development of antiviral agents. Epidemiology and control of viral infections. Laboratory diagnosis of viral diseases. Viral diseases (assortment).Viruses and biotechnology;

Literature

TIMBURY, Morag C. Notes on medical virology. 11th ed. New York: Churchill Livingstone, 1997, 196 s. ISBN 0-443-05846-6. info
BEDNÁŘ, Marek. Lékařská mikrobiologie : bakteriologie, virologie, parazitologie. 1. vyd. Praha: Marvil, 1996, 558 s. info
ROSYPAL, Stanislav. Bakteriologie a virologie. 1. vyd. Praha: Scientia, 1994, 67 s. ISBN 80-85827-16-6. info
LEVY, Jay A., Heinz FRAENKEL-CONRAT and Robert A. OWENS. Virology. 3rd ed. Englewood Cliffs: Prentice-Hall, 1994, xii, 447 s. ISBN 0-13-953753-8. info
CANN, Alan J. Principles of molecular virology. London: Academic Press, 1993, 234 s. ISBN 0-12-158531-X. info

Assessment methods (in Czech)

Přednáška.Zkouška ústní.

Language of instruction

Czech

Further comments (probably available only in Czech)

The course is taught annually.
The course is taught: every week.

Listed among pre-requisites of other courses

The course is also listed under the following terms Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.

Bi5420 General virology

Faculty of Science
Autumn 2011

The course is not taught in Autumn 2011

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

RNDr. Danuška Horáková, CSc. (lecturer)
doc. Mgr. Monika Vítězová, Ph.D. (lecturer)

Guaranteed by

RNDr. Danuška Horáková, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Danuška Horáková, CSc.

Prerequisites (in Czech)

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

Cellular and Molecular Diagnostics (programme PřF, B-BI)
General Biology (programme PřF, B-BI, specialization Microbiology)
Special Biology (programme PřF, B-EXB)
Special Biology (programme PřF, B-EXB, specialization Mikrobiology a Molecular Biotechnology)

Course objectives

Syllabus

Introduction. Structure of viruses - morphology and chemical composition of viruses, inactivation of viruses. Classification of viruses - criteria of classificationanimal viruses, plant viruses,insect viruses, bacteriophages. Methods of investigations of viruses, cultivation and assay of viruses. The viral multiplication cycle - adsorption, penetration, transcription, translation, replication of viral nucleic acid, morphogenesis. Reproduction of animal viruses. Reproduction of plant viruses. Reproduction of bacteriophages. Viral genetics - mutation, abortive infections and defective viruses, genetic interaction between viruses, interactions between viral gene products, the genetic basis of virulence. Pathogenesis of viral infections - pathogenicity and virulence, routes of entry, mechanisms of spread in the organismus, virus shedding. Host responses to viral infections, antiviral immunological mechanisms, immunization. Chemotherapy of viral diseases - nucleoside analogs, other antiviral agents, strategy for development of antiviral agents. Epidemiology and control of viral infections. Laboratory diagnosis of viral diseases. Viral diseases (assortment).Viruses and biotechnology;

Literature

TIMBURY, Morag C. Notes on medical virology. 11th ed. New York: Churchill Livingstone, 1997, 196 s. ISBN 0-443-05846-6. info
BEDNÁŘ, Marek. Lékařská mikrobiologie : bakteriologie, virologie, parazitologie. 1. vyd. Praha: Marvil, 1996, 558 s. info
ROSYPAL, Stanislav. Bakteriologie a virologie. 1. vyd. Praha: Scientia, 1994, 67 s. ISBN 80-85827-16-6. info
LEVY, Jay A., Heinz FRAENKEL-CONRAT and Robert A. OWENS. Virology. 3rd ed. Englewood Cliffs: Prentice-Hall, 1994, xii, 447 s. ISBN 0-13-953753-8. info
CANN, Alan J. Principles of molecular virology. London: Academic Press, 1993, 234 s. ISBN 0-12-158531-X. info

Assessment methods (in Czech)

Přednáška.Zkouška ústní.

Language of instruction

Czech

Further comments (probably available only in Czech)

The course is taught annually.
The course is taught: every week.

Listed among pre-requisites of other courses

Bi5420 General virology

Faculty of Science
Autumn 2010

The course is not taught in Autumn 2010

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

RNDr. Danuška Horáková, CSc. (lecturer)
doc. Mgr. Monika Vítězová, Ph.D. (lecturer)

Guaranteed by

RNDr. Danuška Horáková, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Danuška Horáková, CSc.

Prerequisites (in Czech)

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

Cellular and Molecular Diagnostics (programme PřF, B-BI)
General Biology (programme PřF, B-BI, specialization Microbiology)

Course objectives

Syllabus

Introduction. Structure of viruses - morphology and chemical composition of viruses, inactivation of viruses. Classification of viruses - criteria of classificationanimal viruses, plant viruses,insect viruses, bacteriophages. Methods of investigations of viruses, cultivation and assay of viruses. The viral multiplication cycle - adsorption, penetration, transcription, translation, replication of viral nucleic acid, morphogenesis. Reproduction of animal viruses. Reproduction of plant viruses. Reproduction of bacteriophages. Viral genetics - mutation, abortive infections and defective viruses, genetic interaction between viruses, interactions between viral gene products, the genetic basis of virulence. Pathogenesis of viral infections - pathogenicity and virulence, routes of entry, mechanisms of spread in the organismus, virus shedding. Host responses to viral infections, antiviral immunological mechanisms, immunization. Chemotherapy of viral diseases - nucleoside analogs, other antiviral agents, strategy for development of antiviral agents. Epidemiology and control of viral infections. Laboratory diagnosis of viral diseases. Viral diseases (assortment).Viruses and biotechnology;

Literature

TIMBURY, Morag C. Notes on medical virology. 11th ed. New York: Churchill Livingstone, 1997, 196 s. ISBN 0-443-05846-6. info
BEDNÁŘ, Marek. Lékařská mikrobiologie : bakteriologie, virologie, parazitologie. 1. vyd. Praha: Marvil, 1996, 558 s. info
ROSYPAL, Stanislav. Bakteriologie a virologie. 1. vyd. Praha: Scientia, 1994, 67 s. ISBN 80-85827-16-6. info
LEVY, Jay A., Heinz FRAENKEL-CONRAT and Robert A. OWENS. Virology. 3rd ed. Englewood Cliffs: Prentice-Hall, 1994, xii, 447 s. ISBN 0-13-953753-8. info
CANN, Alan J. Principles of molecular virology. London: Academic Press, 1993, 234 s. ISBN 0-12-158531-X. info

Assessment methods (in Czech)

Přednáška.Zkouška ústní.

Language of instruction

Czech

Further comments (probably available only in Czech)

The course is taught annually.
The course is taught: every week.

Listed among pre-requisites of other courses

Bi5420 General virology

Faculty of Science
Autumn 2009

The course is not taught in Autumn 2009

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

RNDr. Danuška Horáková, CSc. (lecturer)
doc. Mgr. Monika Vítězová, Ph.D. (lecturer)

Guaranteed by

RNDr. Danuška Horáková, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Danuška Horáková, CSc.

Prerequisites (in Czech)

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

Cellular and Molecular Diagnostics (programme PřF, B-BI)
General Biology (programme PřF, B-BI, specialization Microbiology)

Course objectives

Syllabus

Introduction. Structure of viruses - morphology and chemical composition of viruses, inactivation of viruses. Classification of viruses - criteria of classificationanimal viruses, plant viruses,insect viruses, bacteriophages. Methods of investigations of viruses, cultivation and assay of viruses. The viral multiplication cycle - adsorption, penetration, transcription, translation, replication of viral nucleic acid, morphogenesis. Reproduction of animal viruses. Reproduction of plant viruses. Reproduction of bacteriophages. Viral genetics - mutation, abortive infections and defective viruses, genetic interaction between viruses, interactions between viral gene products, the genetic basis of virulence. Pathogenesis of viral infections - pathogenicity and virulence, routes of entry, mechanisms of spread in the organismus, virus shedding. Host responses to viral infections, antiviral immunological mechanisms, immunization. Chemotherapy of viral diseases - nucleoside analogs, other antiviral agents, strategy for development of antiviral agents. Epidemiology and control of viral infections. Laboratory diagnosis of viral diseases. Viral diseases (assortment).Viruses and biotechnology;

Literature

TIMBURY, Morag C. Notes on medical virology. 11th ed. New York: Churchill Livingstone, 1997, 196 s. ISBN 0-443-05846-6. info
BEDNÁŘ, Marek. Lékařská mikrobiologie : bakteriologie, virologie, parazitologie. 1. vyd. Praha: Marvil, 1996, 558 s. info
ROSYPAL, Stanislav. Bakteriologie a virologie. 1. vyd. Praha: Scientia, 1994, 67 s. ISBN 80-85827-16-6. info
LEVY, Jay A., Heinz FRAENKEL-CONRAT and Robert A. OWENS. Virology. 3rd ed. Englewood Cliffs: Prentice-Hall, 1994, xii, 447 s. ISBN 0-13-953753-8. info
CANN, Alan J. Principles of molecular virology. London: Academic Press, 1993, 234 s. ISBN 0-12-158531-X. info

Assessment methods (in Czech)

Přednáška.Zkouška ústní.

Language of instruction

Czech

Further comments (probably available only in Czech)

The course is taught annually.
The course is taught: every week.

Listed among pre-requisites of other courses

Bi5420 General virology

Faculty of Science
Autumn 2008

The course is not taught in Autumn 2008

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

RNDr. Danuška Horáková, CSc. (lecturer)
doc. Mgr. Monika Vítězová, Ph.D. (lecturer)

Guaranteed by

RNDr. Danuška Horáková, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Danuška Horáková, CSc.

Prerequisites (in Czech)

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

Cellular and Molecular Diagnostics (programme PřF, B-BI)
General Biology (programme PřF, B-BI, specialization Microbiology)

Course objectives

Syllabus

Introduction. Structure of viruses - morphology and chemical composition of viruses, inactivation of viruses. Classification of viruses - criteria of classificationanimal viruses, plant viruses,insect viruses, bacteriophages. Methods of investigations of viruses, cultivation and assay of viruses. The viral multiplication cycle - adsorption, penetration, transcription, translation, replication of viral nucleic acid, morphogenesis. Reproduction of animal viruses. Reproduction of plant viruses. Reproduction of bacteriophages. Viral genetics - mutation, abortive infections and defective viruses, genetic interaction between viruses, interactions between viral gene products, the genetic basis of virulence. Pathogenesis of viral infections - pathogenicity and virulence, routes of entry, mechanisms of spread in the organismus, virus shedding. Host responses to viral infections, antiviral immunological mechanisms, immunization. Chemotherapy of viral diseases - nucleoside analogs, other antiviral agents, strategy for development of antiviral agents. Epidemiology and control of viral infections. Laboratory diagnosis of viral diseases. Viral diseases (assortment).Viruses and biotechnology;

Literature

TIMBURY, Morag C. Notes on medical virology. 11th ed. New York: Churchill Livingstone, 1997, 196 s. ISBN 0-443-05846-6. info
BEDNÁŘ, Marek. Lékařská mikrobiologie : bakteriologie, virologie, parazitologie. 1. vyd. Praha: Marvil, 1996, 558 s. info
ROSYPAL, Stanislav. Bakteriologie a virologie. 1. vyd. Praha: Scientia, 1994, 67 s. ISBN 80-85827-16-6. info
LEVY, Jay A., Heinz FRAENKEL-CONRAT and Robert A. OWENS. Virology. 3rd ed. Englewood Cliffs: Prentice-Hall, 1994, xii, 447 s. ISBN 0-13-953753-8. info
CANN, Alan J. Principles of molecular virology. London: Academic Press, 1993, 234 s. ISBN 0-12-158531-X. info

Assessment methods (in Czech)

Přednáška.Zkouška ústní.

Language of instruction

Czech

Further comments (probably available only in Czech)

The course is taught annually.
The course is taught: every week.

Listed among pre-requisites of other courses

Bi5420 General virology

Faculty of Science
Autumn 2007

The course is not taught in Autumn 2007

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

RNDr. Danuška Horáková, CSc. (lecturer)
doc. Mgr. Monika Vítězová, Ph.D. (lecturer)

Guaranteed by

RNDr. Danuška Horáková, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Danuška Horáková, CSc.

Prerequisites (in Czech)

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

Cellular and Molecular Diagnostics (programme PřF, B-BI)
General Biology (programme PřF, B-BI, specialization Microbiology)

Course objectives

Syllabus

Introduction. Structure of viruses - morphology and chemical composition of viruses, inactivation of viruses. Classification of viruses - criteria of classificationanimal viruses, plant viruses,insect viruses, bacteriophages. Methods of investigations of viruses, cultivation and assay of viruses. The viral multiplication cycle - adsorption, penetration, transcription, translation, replication of viral nucleic acid, morphogenesis. Reproduction of animal viruses. Reproduction of plant viruses. Reproduction of bacteriophages. Viral genetics - mutation, abortive infections and defective viruses, genetic interaction between viruses, interactions between viral gene products, the genetic basis of virulence. Pathogenesis of viral infections - pathogenicity and virulence, routes of entry, mechanisms of spread in the organismus, virus shedding. Host responses to viral infections, antiviral immunological mechanisms, immunization. Chemotherapy of viral diseases - nucleoside analogs, other antiviral agents, strategy for development of antiviral agents. Epidemiology and control of viral infections. Laboratory diagnosis of viral diseases. Viral diseases (assortment).Viruses and biotechnology;

Literature

TIMBURY, Morag C. Notes on medical virology. 11th ed. New York: Churchill Livingstone, 1997, 196 s. ISBN 0-443-05846-6. info
BEDNÁŘ, Marek. Lékařská mikrobiologie : bakteriologie, virologie, parazitologie. 1. vyd. Praha: Marvil, 1996, 558 s. info
ROSYPAL, Stanislav. Bakteriologie a virologie. 1. vyd. Praha: Scientia, 1994, 67 s. ISBN 80-85827-16-6. info
LEVY, Jay A., Heinz FRAENKEL-CONRAT and Robert A. OWENS. Virology. 3rd ed. Englewood Cliffs: Prentice-Hall, 1994, xii, 447 s. ISBN 0-13-953753-8. info
CANN, Alan J. Principles of molecular virology. London: Academic Press, 1993, 234 s. ISBN 0-12-158531-X. info

Assessment methods (in Czech)

Přednáška.Zkouška ústní.

Language of instruction

Czech

Further comments (probably available only in Czech)

The course is taught annually.
The course is taught: every week.

Listed among pre-requisites of other courses

Bi5420 General virology

Faculty of Science
Autumn 2011 - acreditation

The course is not taught in Autumn 2011 - acreditation

The information about the term Autumn 2011 - acreditation is not made public

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

RNDr. Danuška Horáková, CSc. (lecturer)
doc. Mgr. Monika Vítězová, Ph.D. (lecturer)

Guaranteed by

RNDr. Danuška Horáková, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Danuška Horáková, CSc.

Prerequisites (in Czech)

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

Cellular and Molecular Diagnostics (programme PřF, B-BI)
General Biology (programme PřF, B-BI, specialization Microbiology)

Course objectives

The aim of the course is to provide knowledge on the world of viruses. At the end of the course students should understand to logics of virus classification, molecular mechanisms of their life cycles and changes they induce in infected cells and organisms.

Syllabus

Introduction. Structure of viruses - morphology and chemical composition of viruses, inactivation of viruses. Classification of viruses - criteria of classificationanimal viruses, plant viruses,insect viruses, bacteriophages. Methods of investigations of viruses, cultivation and assay of viruses. The viral multiplication cycle - adsorption, penetration, transcription, translation, replication of viral nucleic acid, morphogenesis. Reproduction of animal viruses. Reproduction of plant viruses. Reproduction of bacteriophages. Viral genetics - mutation, abortive infections and defective viruses, genetic interaction between viruses, interactions between viral gene products, the genetic basis of virulence. Pathogenesis of viral infections - pathogenicity and virulence, routes of entry, mechanisms of spread in the organismus, virus shedding. Host responses to viral infections, antiviral immunological mechanisms, immunization. Chemotherapy of viral diseases - nucleoside analogs, other antiviral agents, strategy for development of antiviral agents. Epidemiology and control of viral infections. Laboratory diagnosis of viral diseases. Viral diseases (assortment).Viruses and biotechnology;

Literature

TIMBURY, Morag C. Notes on medical virology. 11th ed. New York: Churchill Livingstone, 1997, 196 s. ISBN 0-443-05846-6. info
BEDNÁŘ, Marek. Lékařská mikrobiologie : bakteriologie, virologie, parazitologie. 1. vyd. Praha: Marvil, 1996, 558 s. info
ROSYPAL, Stanislav. Bakteriologie a virologie. 1. vyd. Praha: Scientia, 1994, 67 s. ISBN 80-85827-16-6. info
LEVY, Jay A., Heinz FRAENKEL-CONRAT and Robert A. OWENS. Virology. 3rd ed. Englewood Cliffs: Prentice-Hall, 1994, xii, 447 s. ISBN 0-13-953753-8. info
CANN, Alan J. Principles of molecular virology. London: Academic Press, 1993, 234 s. ISBN 0-12-158531-X. info

Teaching methods

lectures followed by brief discussions

Assessment methods

Classification is based on oral examination.

Language of instruction

Czech

Further comments (probably available only in Czech)

The course is taught annually.
The course is taught: every week.

Listed among pre-requisites of other courses

Bi5420 General virology

Faculty of Science
Autumn 2010 - only for the accreditation

The course is not taught in Autumn 2010 - only for the accreditation

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

RNDr. Danuška Horáková, CSc. (lecturer)
doc. Mgr. Monika Vítězová, Ph.D. (lecturer)

Guaranteed by

RNDr. Danuška Horáková, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Danuška Horáková, CSc.

Prerequisites (in Czech)

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

Cellular and Molecular Diagnostics (programme PřF, B-BI)
General Biology (programme PřF, B-BI, specialization Microbiology)

Course objectives

Syllabus

Introduction. Structure of viruses - morphology and chemical composition of viruses, inactivation of viruses. Classification of viruses - criteria of classificationanimal viruses, plant viruses,insect viruses, bacteriophages. Methods of investigations of viruses, cultivation and assay of viruses. The viral multiplication cycle - adsorption, penetration, transcription, translation, replication of viral nucleic acid, morphogenesis. Reproduction of animal viruses. Reproduction of plant viruses. Reproduction of bacteriophages. Viral genetics - mutation, abortive infections and defective viruses, genetic interaction between viruses, interactions between viral gene products, the genetic basis of virulence. Pathogenesis of viral infections - pathogenicity and virulence, routes of entry, mechanisms of spread in the organismus, virus shedding. Host responses to viral infections, antiviral immunological mechanisms, immunization. Chemotherapy of viral diseases - nucleoside analogs, other antiviral agents, strategy for development of antiviral agents. Epidemiology and control of viral infections. Laboratory diagnosis of viral diseases. Viral diseases (assortment).Viruses and biotechnology;

Literature

TIMBURY, Morag C. Notes on medical virology. 11th ed. New York: Churchill Livingstone, 1997, 196 s. ISBN 0-443-05846-6. info
BEDNÁŘ, Marek. Lékařská mikrobiologie : bakteriologie, virologie, parazitologie. 1. vyd. Praha: Marvil, 1996, 558 s. info
ROSYPAL, Stanislav. Bakteriologie a virologie. 1. vyd. Praha: Scientia, 1994, 67 s. ISBN 80-85827-16-6. info
LEVY, Jay A., Heinz FRAENKEL-CONRAT and Robert A. OWENS. Virology. 3rd ed. Englewood Cliffs: Prentice-Hall, 1994, xii, 447 s. ISBN 0-13-953753-8. info
CANN, Alan J. Principles of molecular virology. London: Academic Press, 1993, 234 s. ISBN 0-12-158531-X. info

Assessment methods (in Czech)

Přednáška.Zkouška ústní.

Language of instruction

Czech

Further comments (probably available only in Czech)

The course is taught annually.
The course is taught: every week.

Listed among pre-requisites of other courses

Bi5420 General virology

Faculty of Science
Autumn 2007 - for the purpose of the accreditation

The course is not taught in Autumn 2007 - for the purpose of the accreditation

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

RNDr. Danuška Horáková, CSc. (lecturer)
doc. Mgr. Monika Vítězová, Ph.D. (lecturer)

Guaranteed by

RNDr. Danuška Horáková, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Danuška Horáková, CSc.

Prerequisites (in Czech)

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

Cellular and Molecular Diagnostics (programme PřF, B-BI)
General Biology (programme PřF, B-BI, specialization Microbiology)

Course objectives

Syllabus

Introduction. Structure of viruses - morphology and chemical composition of viruses, inactivation of viruses. Classification of viruses - criteria of classificationanimal viruses, plant viruses,insect viruses, bacteriophages. Methods of investigations of viruses, cultivation and assay of viruses. The viral multiplication cycle - adsorption, penetration, transcription, translation, replication of viral nucleic acid, morphogenesis. Reproduction of animal viruses. Reproduction of plant viruses. Reproduction of bacteriophages. Viral genetics - mutation, abortive infections and defective viruses, genetic interaction between viruses, interactions between viral gene products, the genetic basis of virulence. Pathogenesis of viral infections - pathogenicity and virulence, routes of entry, mechanisms of spread in the organismus, virus shedding. Host responses to viral infections, antiviral immunological mechanisms, immunization. Chemotherapy of viral diseases - nucleoside analogs, other antiviral agents, strategy for development of antiviral agents. Epidemiology and control of viral infections. Laboratory diagnosis of viral diseases. Viral diseases (assortment).Viruses and biotechnology;

Literature

TIMBURY, Morag C. Notes on medical virology. 11th ed. New York: Churchill Livingstone, 1997, 196 s. ISBN 0-443-05846-6. info
BEDNÁŘ, Marek. Lékařská mikrobiologie : bakteriologie, virologie, parazitologie. 1. vyd. Praha: Marvil, 1996, 558 s. info
ROSYPAL, Stanislav. Bakteriologie a virologie. 1. vyd. Praha: Scientia, 1994, 67 s. ISBN 80-85827-16-6. info
LEVY, Jay A., Heinz FRAENKEL-CONRAT and Robert A. OWENS. Virology. 3rd ed. Englewood Cliffs: Prentice-Hall, 1994, xii, 447 s. ISBN 0-13-953753-8. info
CANN, Alan J. Principles of molecular virology. London: Academic Press, 1993, 234 s. ISBN 0-12-158531-X. info

Assessment methods (in Czech)

Přednáška.Zkouška ústní.

Language of instruction

Czech

Further comments (probably available only in Czech)

The course is taught annually.
The course is taught: every week.

Listed among pre-requisites of other courses

Enrolment Statistics (recent)

Course Information

Bi5420 General virology

Bi5420 General virology

Bi5420 General virology

Bi5420 General virology

Bi5420 General virology

Bi5420 General virology

Bi5420 General virology

Bi5420 General virology

Bi5420 General virology

Bi5420 General virology

Bi5420 General virology

Bi5420 General virology

Bi5420 General virology

Bi5420 General virology

Bi5420 General virology

Bi5420 General virology

Bi5420 General virology

Bi5420 General virology

Bi5420 General virology

Bi5420 General virology

Bi5420 General virology

Bi5420 General virology

Bi5420 General virology

Bi5420 General virology

Bi5420 General virology

Bi5420 General virology

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