Course Information

Bi6290 Human paleogenetics

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

RNDr. Pavel Lízal, Ph.D. (lecturer)

Guaranteed by

RNDr. Pavel Lízal, Ph.D.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Pavel Lízal, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science

Prerequisites

Fundamental knowledge of basic genetics and molecular biology on the level of secondary school.

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 13 fields of study the course is directly associated with, display

Course objectives

At the end of the course students should be able to:
- analyse genetic evidence of modern human origins by study of recent and archaic populations
- formulate answers to questions such as: Who is our common ancestor? When and where did our ancestors live? How much we had ancestors?

Learning outcomes

- formulate answers to questions such as: Who is our common ancestor? When and where did our ancestors live? How much we had ancestors?

Syllabus

• 1) Genetics, antrophology, paleogenetics.
• 2) Evolution and genetics history (Measures of genetic variation, How does evolution work?, Genetics and History - two examples).
• 3) Evolution of early hominid and genus Homo, Models of modern human origins.
• 4) In search of our common ancestor (mitochondrial Eve, chromosome Y and other genes analysis).
• 5) Genetic diversity and recent human evolution.
• 6) Genetic differences between human populations
• 7) How many ancestors? (estimating ancient population size, a Pleistocene population explosion).
• 8) Neanderthal DNA (Discovery of Neanderthal DNA, Were Neanderthals a separate species or different subspecies? Sequencing of Neanderthal DNA.).
• 9) Summary and new model "Mostly out of Africa"

Literature

• J. H. Relethford: Genetics and the search for modern human origins. Wiley-Liss, Inc., 2001
• MIELKE, James H., Lyle W. KONIGSBERG and John RELETHFORD. Human biological variation. New York, N.Y.: Oxford University Press, 2006, xiv, 418. ISBN 0195188713. info
• RELETHFORD, John. Reflections of our past : how human history is revealed in our genes. Boulder, Colo.: Westview Press, 2004, xi, 257. ISBN 0813339588. info

Teaching methods

Lectures with power point presentations

Assessment methods

Attendance in lectures.
Write exam.

Language of instruction

Czech

Further comments (probably available only in Czech)

The course is taught annually.
The course is taught: every week.

Teacher's information

https://youtu.be/JvY7KPJNEkw

Bi6290 Human paleogenetics

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

RNDr. Pavel Lízal, Ph.D. (lecturer)

Guaranteed by

RNDr. Pavel Lízal, Ph.D.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Pavel Lízal, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science

Timetable

Mon 19. 2. to Sun 26. 5. Tue 13:00–14:50 B11/306

Prerequisites

Fundamental knowledge of basic genetics and molecular biology on the level of secondary school.

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 13 fields of study the course is directly associated with, display

Course objectives

At the end of the course students should be able to:
- analyse genetic evidence of modern human origins by study of recent and archaic populations
- formulate answers to questions such as: Who is our common ancestor? When and where did our ancestors live? How much we had ancestors?

Learning outcomes

- formulate answers to questions such as: Who is our common ancestor? When and where did our ancestors live? How much we had ancestors?

Syllabus

• 1) Genetics, antrophology, paleogenetics.
• 2) Evolution and genetics history (Measures of genetic variation, How does evolution work?, Genetics and History - two examples).
• 3) Evolution of early hominid and genus Homo, Models of modern human origins.
• 4) In search of our common ancestor (mitochondrial Eve, chromosome Y and other genes analysis).
• 5) Genetic diversity and recent human evolution.
• 6) Genetic differences between human populations
• 7) How many ancestors? (estimating ancient population size, a Pleistocene population explosion).
• 8) Neanderthal DNA (Discovery of Neanderthal DNA, Were Neanderthals a separate species or different subspecies? Sequencing of Neanderthal DNA.).
• 9) Summary and new model "Mostly out of Africa"

Literature

• J. H. Relethford: Genetics and the search for modern human origins. Wiley-Liss, Inc., 2001
• MIELKE, James H., Lyle W. KONIGSBERG and John RELETHFORD. Human biological variation. New York, N.Y.: Oxford University Press, 2006, xiv, 418. ISBN 0195188713. info
• RELETHFORD, John. Reflections of our past : how human history is revealed in our genes. Boulder, Colo.: Westview Press, 2004, xi, 257. ISBN 0813339588. info

Teaching methods

Lectures with power point presentations

Assessment methods

Attendance in lectures.
Write exam.

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Teacher's information

https://youtu.be/JvY7KPJNEkw

Bi6290 Human paleogenetics

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

RNDr. Pavel Lízal, Ph.D. (lecturer)

Guaranteed by

RNDr. Pavel Lízal, Ph.D.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Pavel Lízal, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science

Timetable

Tue 13:00–14:50 B11/306

Prerequisites

Fundamental knowledge of basic genetics and molecular biology on the level of secondary school.

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 13 fields of study the course is directly associated with, display

Course objectives

At the end of the course students should be able to:
- analyse genetic evidence of modern human origins by study of recent and archaic populations
- formulate answers to questions such as: Who is our common ancestor? When and where did our ancestors live? How much we had ancestors?

Learning outcomes

- formulate answers to questions such as: Who is our common ancestor? When and where did our ancestors live? How much we had ancestors?

Syllabus

• 1) Genetics, antrophology, paleogenetics.
• 2) Evolution and genetics history (Measures of genetic variation, How does evolution work?, Genetics and History - two examples).
• 3) Evolution of early hominid and genus Homo, Models of modern human origins.
• 4) In search of our common ancestor (mitochondrial Eve, chromosome Y and other genes analysis).
• 5) Genetic diversity and recent human evolution.
• 6) Genetic differences between human populations
• 7) How many ancestors? (estimating ancient population size, a Pleistocene population explosion).
• 8) Neanderthal DNA (Discovery of Neanderthal DNA, Were Neanderthals a separate species or different subspecies? Sequencing of Neanderthal DNA.).
• 9) Summary and new model "Mostly out of Africa"

Literature

• J. H. Relethford: Genetics and the search for modern human origins. Wiley-Liss, Inc., 2001
• MIELKE, James H., Lyle W. KONIGSBERG and John RELETHFORD. Human biological variation. New York, N.Y.: Oxford University Press, 2006, xiv, 418. ISBN 0195188713. info
• RELETHFORD, John. Reflections of our past : how human history is revealed in our genes. Boulder, Colo.: Westview Press, 2004, xi, 257. ISBN 0813339588. info

Teaching methods

Lectures with power point presentations

Assessment methods

Attendance in lectures.
Write exam.

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Teacher's information

https://youtu.be/JvY7KPJNEkw

Bi6290 Human paleogenetics

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

RNDr. Pavel Lízal, Ph.D. (lecturer)

Guaranteed by

RNDr. Pavel Lízal, Ph.D.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Pavel Lízal, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science

Timetable

Tue 13:00–14:50 B11/306

Prerequisites

Fundamental knowledge of basic genetics and molecular biology on the level of secondary school.

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 13 fields of study the course is directly associated with, display

Course objectives

At the end of the course students should be able to:
- analyse genetic evidence of modern human origins by study of recent and archaic populations
- formulate answers to questions such as: Who is our common ancestor? When and where did our ancestors live? How much we had ancestors?

Learning outcomes

- formulate answers to questions such as: Who is our common ancestor? When and where did our ancestors live? How much we had ancestors?

Syllabus

• 1) Genetics, antrophology, paleogenetics.
• 2) Evolution and genetics history (Measures of genetic variation, How does evolution work?, Genetics and History - two examples).
• 3) Evolution of early hominid and genus Homo, Models of modern human origins.
• 4) In search of our common ancestor (mitochondrial Eve, chromosome Y and other genes analysis).
• 5) Genetic diversity and recent human evolution.
• 6) Genetic differences between human populations
• 7) How many ancestors? (estimating ancient population size, a Pleistocene population explosion).
• 8) Neanderthal DNA (Discovery of Neanderthal DNA, Were Neanderthals a separate species or different subspecies? Sequencing of Neanderthal DNA.).
• 9) Summary and new model "Mostly out of Africa"

Literature

• J. H. Relethford: Genetics and the search for modern human origins. Wiley-Liss, Inc., 2001
• MIELKE, James H., Lyle W. KONIGSBERG and John RELETHFORD. Human biological variation. New York, N.Y.: Oxford University Press, 2006, xiv, 418. ISBN 0195188713. info
• RELETHFORD, John. Reflections of our past : how human history is revealed in our genes. Boulder, Colo.: Westview Press, 2004, xi, 257. ISBN 0813339588. info

Teaching methods

Lectures with power point presentations

Assessment methods

Attendance in lectures.
Oral exam.

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Teacher's information

https://youtu.be/JvY7KPJNEkw

Bi6290 Human paleogenetics

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

RNDr. Pavel Lízal, Ph.D. (lecturer)

Guaranteed by

RNDr. Pavel Lízal, Ph.D.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Pavel Lízal, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science

Timetable

Mon 1. 3. to Fri 14. 5. Tue 13:00–14:50 online_B1

Prerequisites

Fundamental knowledge of basic genetics and molecular biology on the level of secondary school.

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 13 fields of study the course is directly associated with, display

Course objectives

At the end of the course students should be able to:
- analyse genetic evidence of modern human origins by study of recent and archaic populations
- formulate answers to questions such as: Who is our common ancestor? When and where did our ancestors live? How much we had ancestors?

Learning outcomes

- formulate answers to questions such as: Who is our common ancestor? When and where did our ancestors live? How much we had ancestors?

Syllabus

• 1) Genetics, antrophology, paleogenetics.
• 2) Evolution and genetics history (Measures of genetic variation, How does evolution work?, Genetics and History - two examples).
• 3) Evolution of early hominid and genus Homo, Models of modern human origins.
• 4) In search of our common ancestor (mitochondrial Eve, chromosome Y and other genes analysis).
• 5) Genetic diversity and recent human evolution.
• 6) Genetic differences between human populations
• 7) How many ancestors? (estimating ancient population size, a Pleistocene population explosion).
• 8) Neanderthal DNA (Discovery of Neanderthal DNA, Were Neanderthals a separate species or different subspecies? Sequencing of Neanderthal DNA.).
• 9) Summary and new model "Mostly out of Africa"

Literature

• J. H. Relethford: Genetics and the search for modern human origins. Wiley-Liss, Inc., 2001
• MIELKE, James H., Lyle W. KONIGSBERG and John RELETHFORD. Human biological variation. New York, N.Y.: Oxford University Press, 2006, xiv, 418. ISBN 0195188713. info
• RELETHFORD, John. Reflections of our past : how human history is revealed in our genes. Boulder, Colo.: Westview Press, 2004, xi, 257. ISBN 0813339588. info

Teaching methods

Lectures with power point presentations

Assessment methods

Attendance in lectures.
Oral exam.

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
Information on completion of the course: Vzhledem k epidemiologické situaci bude zkouška probíhat dálkově pomocí MS Teams.
The course is taught annually.

Teacher's information

https://youtu.be/JvY7KPJNEkw

Bi6290 Human paleogenetics

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

RNDr. Pavel Lízal, Ph.D. (lecturer)

Guaranteed by

RNDr. Pavel Lízal, Ph.D.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Pavel Lízal, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science

Timetable

Tue 13:00–14:50 B11/306

Prerequisites

Fundamental knowledge of basic genetics and molecular biology on the level of secondary school.

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 13 fields of study the course is directly associated with, display

Course objectives

At the end of the course students should be able to:
- analyse genetic evidence of modern human origins by study of recent and archaic populations
- formulate answers to questions such as: Who is our common ancestor? When and where did our ancestors live? How much we had ancestors?

Learning outcomes

- formulate answers to questions such as: Who is our common ancestor? When and where did our ancestors live? How much we had ancestors?

Syllabus

• 1) Genetics, antrophology, paleogenetics.
• 2) Evolution and genetics history (Measures of genetic variation, How does evolution work?, Genetics and History - two examples).
• 3) Evolution of early hominid and genus Homo, Models of modern human origins.
• 4) In search of our common ancestor (mitochondrial Eve, chromosome Y and other genes analysis).
• 5) Genetic diversity and recent human evolution.
• 6) Genetic differences between human populations
• 7) How many ancestors? (estimating ancient population size, a Pleistocene population explosion).
• 8) Neanderthal DNA (Discovery of Neanderthal DNA, Were Neanderthals a separate species or different subspecies? Sequencing of Neanderthal DNA.).
• 9) Summary and new model "Mostly out of Africa"

Literature

• J. H. Relethford: Genetics and the search for modern human origins. Wiley-Liss, Inc., 2001
• MIELKE, James H., Lyle W. KONIGSBERG and John RELETHFORD. Human biological variation. New York, N.Y.: Oxford University Press, 2006, xiv, 418. ISBN 0195188713. info
• RELETHFORD, John. Reflections of our past : how human history is revealed in our genes. Boulder, Colo.: Westview Press, 2004, xi, 257. ISBN 0813339588. info

Teaching methods

Lectures with power point presentations

Assessment methods

Attendance in lectures.
Oral exam.

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Teacher's information

https://youtu.be/JvY7KPJNEkw

Bi6290 Human paleogenetics

Extent and Intensity

2/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

RNDr. Pavel Lízal, Ph.D. (lecturer)

Guaranteed by

RNDr. Pavel Lízal, Ph.D.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Pavel Lízal, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science

Timetable

Mon 18. 2. to Fri 17. 5. Tue 13:00–14:50 B11/306

Prerequisites

Fundamental knowledge of basic genetics and molecular biology on the level of secondary school.

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 13 fields of study the course is directly associated with, display

Course objectives

At the end of the course students should be able to:
- analyse genetic evidence of modern human origins by study of recent and archaic populations
- formulate answers to questions such as: Who is our common ancestor? When and where did our ancestors live? How much we had ancestors?

Syllabus

• 1) Genetics, antrophology, paleogenetics.
• 2) Evolution and genetics history (Measures of genetic variation, How does evolution work?, Genetics and History - two examples).
• 3) Evolution of early hominid and genus Homo, Models of modern human origins.
• 4) In search of our common ancestor (mitochondrial Eve, chromosome Y and other genes analysis).
• 5) Genetic diversity and recent human evolution.
• 6) Genetic differences between human populations
• 7) How many ancestors? (estimating ancient population size, a Pleistocene population explosion).
• 8) Neanderthal DNA (Discovery of Neanderthal DNA, Were Neanderthals a separate species or different subspecies? Sequencing of Neanderthal DNA.).
• 9) Summary and new model "Mostly out of Africa"

Literature

• J. H. Relethford: Genetics and the search for modern human origins. Wiley-Liss, Inc., 2001
• MIELKE, James H., Lyle W. KONIGSBERG and John RELETHFORD. Human biological variation. New York, N.Y.: Oxford University Press, 2006, xiv, 418. ISBN 0195188713. info
• RELETHFORD, John. Reflections of our past : how human history is revealed in our genes. Boulder, Colo.: Westview Press, 2004, xi, 257. ISBN 0813339588. info

Teaching methods

Lectures with power point presentations

Assessment methods

Attendance in lectures.
Oral exam.

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Teacher's information

https://is.muni.cz/auth/el/1431/jaro2014/Bi6290/um/paleogen-web/index.html

Bi6290 Human paleogenetics

Extent and Intensity

2/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

RNDr. Pavel Lízal, Ph.D. (lecturer)

Guaranteed by

RNDr. Pavel Lízal, Ph.D.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Pavel Lízal, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science

Timetable

Tue 13:00–14:50 B11/306

Prerequisites

Fundamental knowledge of basic genetics and molecular biology on the level of secondary school.

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 13 fields of study the course is directly associated with, display

Course objectives

At the end of the course students should be able to:
- analyse genetic evidence of modern human origins by study of recent and archaic populations
- formulate answers to questions such as: Who is our common ancestor? When and where did our ancestors live? How much we had ancestors?

Syllabus

• 1) Genetics, antrophology, paleogenetics.
• 2) Evolution and genetics history (Measures of genetic variation, How does evolution work?, Genetics and History - two examples).
• 3) Evolution of early hominid and genus Homo, Models of modern human origins.
• 4) In search of our common ancestor (mitochondrial Eve, chromosome Y and other genes analysis).
• 5) Genetic diversity and recent human evolution.
• 6) Genetic differences between human populations
• 7) How many ancestors? (estimating ancient population size, a Pleistocene population explosion).
• 8) Neanderthal DNA (Discovery of Neanderthal DNA, Were Neanderthals a separate species or different subspecies? Sequencing of Neanderthal DNA.).
• 9) Summary and new model "Mostly out of Africa"

Literature

• J. H. Relethford: Genetics and the search for modern human origins. Wiley-Liss, Inc., 2001
• MIELKE, James H., Lyle W. KONIGSBERG and John RELETHFORD. Human biological variation. New York, N.Y.: Oxford University Press, 2006, xiv, 418. ISBN 0195188713. info
• RELETHFORD, John. Reflections of our past : how human history is revealed in our genes. Boulder, Colo.: Westview Press, 2004, xi, 257. ISBN 0813339588. info

Teaching methods

Lectures with power point presentations

Assessment methods

Attendance in lectures.
Oral exam.

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Teacher's information

https://is.muni.cz/auth/el/1431/jaro2014/Bi6290/um/paleogen-web/index.html

Bi6290 Human paleogenetics

Extent and Intensity

2/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

RNDr. Pavel Lízal, Ph.D. (lecturer)

Guaranteed by

RNDr. Pavel Lízal, Ph.D.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Pavel Lízal, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science

Timetable

Mon 20. 2. to Mon 22. 5. Tue 16:00–17:50 B11/306

Prerequisites

Fundamental knowledge of basic genetics and molecular biology on the level of secondary school.

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 13 fields of study the course is directly associated with, display

Course objectives

At the end of the course students should be able to:
- analyse genetic evidence of modern human origins by study of recent and archaic populations
- formulate answers to questions such as: Who is our common ancestor? When and where did our ancestors live? How much we had ancestors?

Syllabus

• 1) Genetics, antrophology, paleogenetics.
• 2) Evolution and genetics history (Measures of genetic variation, How does evolution work?, Genetics and History - two examples).
• 3) Evolution of early hominid and genus Homo, Models of modern human origins.
• 4) In search of our common ancestor (mitochondrial Eve, chromosome Y and other genes analysis).
• 5) Genetic diversity and recent human evolution.
• 6) Genetic differences between human populations
• 7) How many ancestors? (estimating ancient population size, a Pleistocene population explosion).
• 8) Neanderthal DNA (Discovery of Neanderthal DNA, Were Neanderthals a separate species or different subspecies? Sequencing of Neanderthal DNA.).
• 9) Summary and new model "Mostly out of Africa"

Literature

• J. H. Relethford: Genetics and the search for modern human origins. Wiley-Liss, Inc., 2001
• MIELKE, James H., Lyle W. KONIGSBERG and John RELETHFORD. Human biological variation. New York, N.Y.: Oxford University Press, 2006, xiv, 418. ISBN 0195188713. info
• RELETHFORD, John. Reflections of our past : how human history is revealed in our genes. Boulder, Colo.: Westview Press, 2004, xi, 257. ISBN 0813339588. info

Teaching methods

Lectures with power point presentations

Assessment methods

Attendance in lectures.
Oral exam.

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Teacher's information

https://is.muni.cz/auth/el/1431/jaro2014/Bi6290/um/paleogen-web/index.html

Bi6290 Human paleogenetics

Extent and Intensity

2/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

RNDr. Pavel Lízal, Ph.D. (lecturer)

Guaranteed by

RNDr. Pavel Lízal, Ph.D.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Pavel Lízal, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science

Timetable

Tue 16:00–17:50 B11/306

Prerequisites

Fundamental knowledge of basic genetics and molecular biology on the level of secondary school.

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 13 fields of study the course is directly associated with, display

Course objectives

At the end of the course students should be able to:
- analyse genetic evidence of modern human origins by study of recent and archaic populations
- formulate answers to questions such as: Who is our common ancestor? When and where did our ancestors live? How much we had ancestors?

Syllabus

• 1) Genetics, antrophology, paleogenetics.
• 2) Evolution and genetics history (Measures of genetic variation, How does evolution work?, Genetics and History - two examples).
• 3) Evolution of early hominid and genus Homo, Models of modern human origins.
• 4) In search of our common ancestor (mitochondrial Eve, chromosome Y and other genes analysis).
• 5) Genetic diversity and recent human evolution.
• 6) Genetic differences between human populations
• 7) How many ancestors? (estimating ancient population size, a Pleistocene population explosion).
• 8) Neanderthal DNA (Discovery of Neanderthal DNA, Were Neanderthals a separate species or different subspecies? Sequencing of Neanderthal DNA.).
• 9) Summary and new model "Mostly out of Africa"

Literature

• J. H. Relethford: Genetics and the search for modern human origins. Wiley-Liss, Inc., 2001
• MIELKE, James H., Lyle W. KONIGSBERG and John RELETHFORD. Human biological variation. New York, N.Y.: Oxford University Press, 2006, xiv, 418. ISBN 0195188713. info
• RELETHFORD, John. Reflections of our past : how human history is revealed in our genes. Boulder, Colo.: Westview Press, 2004, xi, 257. ISBN 0813339588. info

Teaching methods

Lectures with power point presentations

Assessment methods

Attendance in lectures.
Oral exam.

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Teacher's information

https://is.muni.cz/auth/el/1431/jaro2014/Bi6290/um/paleogen-web/index.html

Bi6290 Human paleogenetics

Extent and Intensity

2/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

RNDr. Pavel Lízal, Ph.D. (lecturer)

Guaranteed by

RNDr. Pavel Lízal, Ph.D.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Pavel Lízal, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science

Timetable

Tue 16:00–17:50 B11/306

Prerequisites

Fundamental knowledge of basic genetics and molecular biology on the level of secondary school.

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 13 fields of study the course is directly associated with, display

Course objectives

At the end of the course students should be able to:
- analyse genetic evidence of modern human origins by study of recent and archaic populations
- formulate answers to questions such as: Who is our common ancestor? When and where did our ancestors live? How much we had ancestors?

Syllabus

• 1) Genetics, antrophology, paleogenetics.
• 2) Evolution and genetics history (Measures of genetic variation, How does evolution work?, Genetics and History - two examples).
• 3) Evolution of early hominid and genus Homo, Models of modern human origins.
• 4) In search of our common ancestor (mitochondrial Eve, chromosome Y and other genes analysis).
• 5) Genetic diversity and recent human evolution.
• 6) Genetic differences between human populations
• 7) How many ancestors? (estimating ancient population size, a Pleistocene population explosion).
• 8) Neanderthal DNA (Discovery of Neanderthal DNA, Were Neanderthals a separate species or different subspecies? Sequencing of Neanderthal DNA.).
• 9) Summary and new model "Mostly out of Africa"

Literature

• J. H. Relethford: Genetics and the search for modern human origins. Wiley-Liss, Inc., 2001
• MIELKE, James H., Lyle W. KONIGSBERG and John RELETHFORD. Human biological variation. New York, N.Y.: Oxford University Press, 2006, xiv, 418. ISBN 0195188713. info
• RELETHFORD, John. Reflections of our past : how human history is revealed in our genes. Boulder, Colo.: Westview Press, 2004, xi, 257. ISBN 0813339588. info

Teaching methods

Lectures with power point presentations

Assessment methods

Attendance in lectures.
Oral exam.

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Teacher's information

https://is.muni.cz/auth/el/1431/jaro2014/Bi6290/um/paleogen-web/index.html

Bi6290 Human paleogenetics

Extent and Intensity

2/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

RNDr. Pavel Lízal, Ph.D. (lecturer)

Guaranteed by

RNDr. Pavel Lízal, Ph.D.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Pavel Lízal, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science

Timetable

Tue 16:00–17:50 B11/306

Prerequisites

Fundamental knowledge of basic genetics and molecular biology on the level of secondary school.

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 13 fields of study the course is directly associated with, display

Course objectives

At the end of the course students should be able to:
- analyse genetic evidence of modern human origins by study of recent and archaic populations
- formulate answers to questions such as: Who is our common ancestor? When and where did our ancestors live? How much we had ancestors?

Syllabus

• 1) Genetics, antrophology, paleogenetics.
• 2) Evolution and genetics history (Measures of genetic variation, How does evolution work?, Genetics and History - two examples).
• 3) Evolution of early hominid and genus Homo, Models of modern human origins.
• 4) In search of our common ancestor (mitochondrial Eve, chromosome Y and other genes analysis).
• 5) Genetic diversity and recent human evolution.
• 6) Genetic differences between human populations
• 7) How many ancestors? (estimating ancient population size, a Pleistocene population explosion).
• 8) Neanderthal DNA (Discovery of Neanderthal DNA, Were Neanderthals a separate species or different subspecies? Sequencing of Neanderthal DNA.).
• 9) Summary and new model "Mostly out of Africa"

Literature

• J. H. Relethford: Genetics and the search for modern human origins. Wiley-Liss, Inc., 2001
• MIELKE, James H., Lyle W. KONIGSBERG and John RELETHFORD. Human biological variation. New York, N.Y.: Oxford University Press, 2006, xiv, 418. ISBN 0195188713. info
• RELETHFORD, John. Reflections of our past : how human history is revealed in our genes. Boulder, Colo.: Westview Press, 2004, xi, 257. ISBN 0813339588. info

Teaching methods

Lectures with power point presentations

Assessment methods

Attendance in lectures.
Oral exam.

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Teacher's information

https://is.muni.cz/auth/el/1431/jaro2014/Bi6290/um/paleogen-web/index.html

Bi6290 Human paleogenetics

Extent and Intensity

2/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

RNDr. Pavel Lízal, Ph.D. (lecturer)

Guaranteed by

RNDr. Pavel Lízal, Ph.D.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Pavel Lízal, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science

Timetable

Tue 16:00–17:50 B11/306

Prerequisites

Fundamental knowledge of basic genetics and molecular biology on the level of secondary school.

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 13 fields of study the course is directly associated with, display

Course objectives

At the end of the course students should be able to:
- analyse genetic evidence of modern human origins by study of recent and archaic populations
- formulate answers to questions such as: Who is our common ancestor? When and where did our ancestors live? How many were ancestors?

Syllabus

• 1) Genetics, antrophology, paleogenetics.
• 2) Evolution and genetics history (Measures of genetic variation, How does evolution work?, Genetics and History - two examples).
• 3) Evolution of early hominid and genus Homo, Models of modern human origins.
• 4) In search of our common ancestor (mitochondrial Eve, chromosome Y and other genes analysis).
• 5) Genetic diversity and recent human evolution.
• 6) Genetic differences between human populations
• 7) How many ancestors? (estimating ancient population size, a Pleistocene population explosion).
• 8) Neanderthal DNA (Discovery Neanderthal DNA, Were Neanderthals a separate species or different subspecies? SEquencing of Neanderthal DNA.).
• 9) Summary and new model "Mostly out of Africa"

Literature

• J. H. Relethford: Genetics and the search for modern human origins. Wiley-Liss, Inc., 2001
• MIELKE, James H., Lyle W. KONIGSBERG and John RELETHFORD. Human biological variation. New York, N.Y.: Oxford University Press, 2006, xiv, 418. ISBN 0195188713. info
• RELETHFORD, John. Reflections of our past : how human history is revealed in our genes. Boulder, Colo.: Westview Press, 2004, xi, 257. ISBN 0813339588. info

Teaching methods

Lectures with power point presentations

Assessment methods

Attendance in lectures.
Oral exam.

Language of instruction

Czech

Further Comments

Study Materials
The course is taught annually.

Teacher's information

http://is.muni.cz/www/2538/sylabus_paleogenetika_cloveka.html

Bi6290 Human paleogenetics

Extent and Intensity

2/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

RNDr. Pavel Lízal, Ph.D. (lecturer)

Guaranteed by

RNDr. Pavel Lízal, Ph.D.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Pavel Lízal, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science

Timetable

Wed 10:00–11:50 B11/306

Prerequisites

Fundamental knowledge of basic genetics and molecular biology on the level of secondary school.

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 18 fields of study the course is directly associated with, display

Course objectives

At the end of the course students should be able to:
- analyse genetic evidence of modern human origins by study of recent and archaic populations
- formulate answers to questions such as: Who is our common ancestor? When and where did our ancestors live? How many were ancestors?

Syllabus

• 1) Genetics, antrophology, paleogenetics.
• 2) Evolution and genetics history (Measures of genetic variation, How does evolution work?, Genetics and History - two examples).
• 3) Evolution of early hominid and genus Homo, Models of modern human origins.
• 4) In search of our common ancestor (mitochondrial Eve, chromosome Y and other genes analysis).
• 5) Genetic diversity and recent human evolution.
• 6) Genetic differences between human populations
• 7) How many ancestors? (estimating ancient population size, a Pleistocene population explosion).
• 8) Neanderthal DNA (Discovery Neanderthal DNA, Were Neanderthals a separate species or different subspecies? SEquencing of Neanderthal DNA.).
• 9) Summary and new model "Mostly out of Africa"

Literature

• J. H. Relethford: Genetics and the search for modern human origins. Wiley-Liss, Inc., 2001
• MIELKE, James H., Lyle W. KONIGSBERG and John RELETHFORD. Human biological variation. New York, N.Y.: Oxford University Press, 2006, xiv, 418. ISBN 0195188713. info
• RELETHFORD, John. Reflections of our past : how human history is revealed in our genes. Boulder, Colo.: Westview Press, 2004, xi, 257. ISBN 0813339588. info

Teaching methods

Lectures with power point presentations

Assessment methods

Attendance in lectures.
Oral exam.

Language of instruction

Czech

Further Comments

Study Materials
The course is taught annually.

Teacher's information

http://is.muni.cz/www/2538/sylabus_paleogenetika_cloveka.html

Bi6290 Human paleogenetics

Extent and Intensity

2/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

RNDr. Pavel Lízal, Ph.D. (lecturer)

Guaranteed by

RNDr. Pavel Lízal, Ph.D.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Pavel Lízal, Ph.D.

Timetable

Tue 14:00–15:50 B11/306

Prerequisites

Fundamental knowledge of basic genetics and molecular biology on the level of secondary school.

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 17 fields of study the course is directly associated with, display

Course objectives

At the end of the course students should be able to:
- analyse genetic evidence of modern human origins by study of recent and archaic populations
- formulate answers to questions such as: Who is our common ancestor? When and where did our ancestors live? How many were ancestors?

Syllabus

• 1) Genetics, antrophology, paleogenetics.
• 2) Evolution and genetics history (Measures of genetic variation, How does evolution work?, Genetics and History - two examples).
• 3) Evolution of early hominid and genus Homo, Models of modern human origins.
• 4) In search of our common ancestor (mitochondrial Eve, chromosome Y and other genes analysis).
• 5) Genetic diversity and recent human evolution.
• 6) Genetic differences between human populations
• 7) How many ancestors? (estimating ancient population size, a Pleistocene population explosion).
• 8) Neanderthal DNA (Discovery Neanderthal DNA, Were Neanderthals a separate species or different subspecies? SEquencing of Neanderthal DNA.).
• 9) Summary and new model "Mostly out of Africa"

Literature

• J. H. Relethford: Genetics and the search for modern human origins. Wiley-Liss, Inc., 2001
• MIELKE, James H., Lyle W. KONIGSBERG and John RELETHFORD. Human biological variation. New York, N.Y.: Oxford University Press, 2006, xiv, 418. ISBN 0195188713. info
• RELETHFORD, John. Reflections of our past : how human history is revealed in our genes. Boulder, Colo.: Westview Press, 2004, xi, 257. ISBN 0813339588. info

Teaching methods

Lectures with power point presentations

Assessment methods

Attendance in lectures.
Oral exam.

Language of instruction

Czech

Further Comments

Study Materials
The course is taught annually.

Teacher's information

http://is.muni.cz/www/2538/sylabus_paleogenetika_cloveka.html

Bi6290 Human paleogenetics

Extent and Intensity

2/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

RNDr. Pavel Lízal, Ph.D. (lecturer)

Guaranteed by

RNDr. Pavel Lízal, Ph.D.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Pavel Lízal, Ph.D.

Timetable

Tue 10:00–11:50 G2,02003

Prerequisites

Fundamental knowledge of basic genetics and molecular biology on the level of secondary school.

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 17 fields of study the course is directly associated with, display

Course objectives

At the end of the course students should be able to:
- analyse genetic evidence of modern human origins by study of recent and archaic populations
- formulate answers to questions such as: Who is our common ancestor? When and where did our ancestors live? How many were ancestors?

Syllabus

• 1) Genetics, antrophology, paleogenetics.
• 2) Evolution and genetics history (Measures of genetic variation, How does evolution work?, Genetics and History - two examples).
• 3) Evolution of early hominid and genus Homo, Models of modern human origins.
• 4) In search of our common ancestor (mitochondrial Eve, chromosome Y and other genes analysis).
• 5) Genetic diversity and recent human evolution.
• 6) Genetic differences between human populations
• 7) How many ancestors? (estimating ancient population size, a Pleistocene population explosion).
• 8) Neanderthal DNA (Discovery Neanderthal DNA, Were Neanderthals a separate species or different subspecies? SEquencing of Neanderthal DNA.).
• 9) Summary and new model "Mostly out of Africa"

Literature

• J. H. Relethford: Genetics and the search for modern human origins. Wiley-Liss, Inc., 2001
• MIELKE, James H., Lyle W. KONIGSBERG and John RELETHFORD. Human biological variation. New York, N.Y.: Oxford University Press, 2006, xiv, 418. ISBN 0195188713. info
• RELETHFORD, John. Reflections of our past : how human history is revealed in our genes. Boulder, Colo.: Westview Press, 2004, xi, 257. ISBN 0813339588. info

Teaching methods

Lectures with power point presentations

Assessment methods

Attendance in lectures.
Oral exam.

Language of instruction

Czech

Further Comments

Study Materials
The course is taught annually.

Teacher's information

http://is.muni.cz/www/2538/sylabus_paleogenetika_cloveka.html

Bi6290 Human paleogenetics

Extent and Intensity

2/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

RNDr. Pavel Lízal, Ph.D. (lecturer)

Guaranteed by

RNDr. Pavel Lízal, Ph.D.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Pavel Lízal, Ph.D.

Timetable

Mon 13:00–14:50 G2,02003

Prerequisites

Fundamental knowledge of basic genetics and molecular biology on the level of secondary school.

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 17 fields of study the course is directly associated with, display

Course objectives

Main objectives:
- to learn the genetic evidence of modern human origins by study of recent and archaic populations
- to answer to questions, for example:
Who is our common ancestor?
When and where did our ancestors live?
How many were ancestors?

Syllabus

• 1) Genetics, antrophology, paleogenetics.
• 2) Evolution and genetics history (Measures of genetic variation, How does evolution work?, Genetics and History - two examples).
• 3) Evolution of early hominid and genus Homo, Models of modern human origins.
• 4) In search of our common ancestor (mitochondrial Eve, chromosome Y and other genes analysis).
• 5) Genetic diversity and recent human evolution.
• 6) Genetic differences between human populations
• 7) How many ancestors? (estimating ancient population size, a Pleistocene population explosion).
• 8) Neanderthal DNA (Discovery Neanderthal DNA, Were Neanderthals a separate species or different subspecies? SEquencing of Neanderthal DNA.).
• 9) Summary and new model "Mostly out of Africa"

Literature

• J. H. Relethford: Genetics and the search for modern human origins. Wiley-Liss, Inc., 2001

Assessment methods

Attendance in lectures.
Oral exam.

Language of instruction

Czech

Further Comments

Study Materials
The course is taught annually.

Teacher's information

http://is.muni.cz/www/2538/sylabus_paleogenetika_cloveka.html

Bi6290 Human paleogenetics

Extent and Intensity

2/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

RNDr. Pavel Lízal, Ph.D. (lecturer)

Guaranteed by

RNDr. Pavel Lízal, Ph.D.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Pavel Lízal, Ph.D.

Timetable

Wed 10:00–11:50 Bpg

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 17 fields of study the course is directly associated with, display

Course objectives (in Czech)

Cílem přednášky je seznámení se s poznatky o evoluci člověka, které byly získány studiem současných a archaických populací člověka propojením antropologických, populačně-genetických a molekulárně-biologických přístupů. Budeme snažit odpovědět na otázky: Kdo jsme a odkud pocházíme? Kdo byl náš předek? Kdy a kde žil? A jak velká byla zakladatelská populace moderního člověka? nebo Jak jsme osídlili svět?

Syllabus (in Czech)

• 1) Genetika a antropologie, paleogenetika. 2) Metody studia historie populací. Mechanizmy evoluce – mutace, přírodní výběr, genetický drift a genový tok. Dva příklady studia historie populací - historie irské populace, odštěpení člověka od lidoopů. 3) Evoluce člověka a modely původu moderního člověka z pohledu evoluce. 5) Hledání našeho společného předka - mitochondriální Eva, kdy a kde žila, analýza chromozomu Y - praotec Adam. Analýza jaderné DNA. 6) Genetická rozmanitost uvnitř populací člověka - geografická distribuce genetické rozmanitosti. 7) Genetické rozmanitost mezi lidskými populacemi - Genetická vzdálenost a její stanovení. Proč jsou subsaharské africké populace geneticky vzdálenější od populací ostatních? Genetická vzdálenost jako důsledek rozdílů v genovém toku (Out of Africa + multiregionální model). Představy o dávné migraci. 8) Kolik jsme měli předků? Velikost populace - celková, reprodukční, efektivní. Ekologické a genetické odhady velikosti dávných populací. Pleistocénní populační exploze. 9) Neandrtálská DNA - Analýza aDNA člověka - nástrahy, problémy, řešení. Analýza první a druhé neandrtálské DNA. Byli Neandrtálci odděleným druhem nebo jen odlišným poddruhem? Křížili jsme se s Neandrtálci? Další nálezy a izolace neandrtálské DNA. Analýza jaderných sekvencí a sekvencování genomu Neandrtálce. 10) Hledání původu moderního člověka - shrnutí, aneb co z toho vyplývá? "Out of Africa" vs. Multiregionální model. Nový model "Mostly out of Africa"

Assessment methods (in Czech)

Předmět je zakončen ústní zkouškou, pro jejíž úspěšné zvládnutí je nezbytným předpokladem pravidelná docházka na přednášky.

Language of instruction

Czech

Further Comments

The course is taught annually.

Teacher's information

http://is.muni.cz/www/2538/sylabus_paleogenetika_cloveka.html

Bi6290 Human paleogenetics

The information about the term spring 2012 - acreditation is not made public

Extent and Intensity

2/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

RNDr. Pavel Lízal, Ph.D. (lecturer)

Guaranteed by

RNDr. Pavel Lízal, Ph.D.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Pavel Lízal, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science

Prerequisites

Fundamental knowledge of basic genetics and molecular biology on the level of secondary school.

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 17 fields of study the course is directly associated with, display

Course objectives

At the end of the course students should be able to:
- analyse genetic evidence of modern human origins by study of recent and archaic populations
- formulate answers to questions such as: Who is our common ancestor? When and where did our ancestors live? How many were ancestors?

Syllabus

• 1) Genetics, antrophology, paleogenetics.
• 2) Evolution and genetics history (Measures of genetic variation, How does evolution work?, Genetics and History - two examples).
• 3) Evolution of early hominid and genus Homo, Models of modern human origins.
• 4) In search of our common ancestor (mitochondrial Eve, chromosome Y and other genes analysis).
• 5) Genetic diversity and recent human evolution.
• 6) Genetic differences between human populations
• 7) How many ancestors? (estimating ancient population size, a Pleistocene population explosion).
• 8) Neanderthal DNA (Discovery Neanderthal DNA, Were Neanderthals a separate species or different subspecies? SEquencing of Neanderthal DNA.).
• 9) Summary and new model "Mostly out of Africa"

Literature

• J. H. Relethford: Genetics and the search for modern human origins. Wiley-Liss, Inc., 2001
• MIELKE, James H., Lyle W. KONIGSBERG and John RELETHFORD. Human biological variation. New York, N.Y.: Oxford University Press, 2006, xiv, 418. ISBN 0195188713. info
• RELETHFORD, John. Reflections of our past : how human history is revealed in our genes. Boulder, Colo.: Westview Press, 2004, xi, 257. ISBN 0813339588. info

Teaching methods

Lectures with power point presentations

Assessment methods

Attendance in lectures.
Oral exam.

Language of instruction

Czech

Further Comments

The course is taught annually.
The course is taught: every week.

Teacher's information

http://is.muni.cz/www/2538/sylabus_paleogenetika_cloveka.html

Bi6290 Human paleogenetics

Extent and Intensity

2/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

RNDr. Pavel Lízal, Ph.D. (lecturer)

Guaranteed by

RNDr. Pavel Lízal, Ph.D.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Pavel Lízal, Ph.D.

Prerequisites

Fundamental knowledge of basic genetics and molecular biology on the level of secondary school.

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 17 fields of study the course is directly associated with, display

Course objectives

At the end of the course students should be able to:
- analyse genetic evidence of modern human origins by study of recent and archaic populations
- formulate answers to questions such as: Who is our common ancestor? When and where did our ancestors live? How many were ancestors?

Syllabus

• 1) Genetics, antrophology, paleogenetics.
• 2) Evolution and genetics history (Measures of genetic variation, How does evolution work?, Genetics and History - two examples).
• 3) Evolution of early hominid and genus Homo, Models of modern human origins.
• 4) In search of our common ancestor (mitochondrial Eve, chromosome Y and other genes analysis).
• 5) Genetic diversity and recent human evolution.
• 6) Genetic differences between human populations
• 7) How many ancestors? (estimating ancient population size, a Pleistocene population explosion).
• 8) Neanderthal DNA (Discovery Neanderthal DNA, Were Neanderthals a separate species or different subspecies? SEquencing of Neanderthal DNA.).
• 9) Summary and new model "Mostly out of Africa"

Literature

• J. H. Relethford: Genetics and the search for modern human origins. Wiley-Liss, Inc., 2001
• MIELKE, James H., Lyle W. KONIGSBERG and John RELETHFORD. Human biological variation. New York, N.Y.: Oxford University Press, 2006, xiv, 418. ISBN 0195188713. info
• RELETHFORD, John. Reflections of our past : how human history is revealed in our genes. Boulder, Colo.: Westview Press, 2004, xi, 257. ISBN 0813339588. info

Teaching methods

Lectures with power point presentations

Assessment methods

Attendance in lectures.
Oral exam.

Language of instruction

Czech

Further Comments

The course is taught annually.
The course is taught: every week.

Teacher's information

http://is.muni.cz/www/2538/sylabus_paleogenetika_cloveka.html

Bi6290 Human paleogenetics

Extent and Intensity

2/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).

Teacher(s)

RNDr. Pavel Lízal, Ph.D. (lecturer)

Guaranteed by

RNDr. Pavel Lízal, Ph.D.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Pavel Lízal, Ph.D.

Prerequisites (in Czech)

Bi4020 Molecular biology && Bi3060 Basic genetics

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 17 fields of study the course is directly associated with, display

Course objectives (in Czech)

Cílem přednášky je seznámení se s poznatky o evoluci člověka, které byly získány studiem současných a archaických populací člověka propojením antropologických, populačně-genetických a molekulárně-biologických přístupů. Na základě paleogenetických výzkumů se budeme snažit odpovědět na otázky jaký byl vývoj člověka, jaké měl člověk předky a kolik jich bylo, jak probíhala migrace a zda-li docházelo ke genetickému prolínání vývojově odlišných populací.

Syllabus (in Czech)

• 1) Genetika a antropologie, paleogenetika (Genetický kód, variabilita, zdroje evoluce, studium historie populací, příklad irské populace) 2) Původ moderního člověka (přehled - evoluce raných hominidů, evoluce rodu Homo, Teorie o původu moderního člověka) 3) Hledání našich společných předků (Mitochondriální Eva, kdy a kde žil náš společný předek, jak velká byla populace) 4) Genetická diverzita a evoluce současného člověka (genetická rozmanitost a evoluce, měření genetické rozmanitosti, genetická rozmanitost člověka a geografické rozmístění, interpretace genetické rozmanitosti africké populace) 5) Genetické rozdíly mezi lidskými populacemi (genetická vzdálenost a evoluce, úrovně genetické diferenciace, studium genetické vzdálenosti mezi populacemi, evoluční interpretace, odhad dávných migrací) 6) Kolik máme předků? (velikost populace a odhad velikosti dávných populací, pleistocénní populační exploze, fylogenetické stromy a expanse populací, expanze a mikrosatelitní DNA, odhad doby expanze, co se dělo před expanzí, speciace a nahrazení, vyhynutí a znovuobnovení lokálních populací) 7) Neandertálská DNA (studium starobylé DNA – postupy, problémy a perspektivy, objevení DNA neandertálského původu – první neandertálská sekvence DNA (Feldhofer), druhá neandertálská sekvence DNA (Mezmaiskaya), Evoluční interpretace – rozmanitost uvnitř neandertálské populace, Byli neandertálci odlišným druhem?, regionální vlivy na neandertálskou DNA, Byly neandertálci poddruhem?) 8) Co z toho všeho vyplývá? (souhrn genetických důkazů, fosilie a pohled populační genetiky, otázky a další vývoj) 9) Další příklady aplikace genetiky v antropologii (např. studium lidského melanocortinového receptoru, molekulární evoluce FOXP2 - jeho vliv na řeč a jazyk, genetická analýza vši podporující domněnku přímého kontaktu moderního a archaického člověka)

Assessment methods (in Czech)

Předmět je zakončen ústní zkouškou, pro jejíž úspěšné zvládnutí je nezbytným předpokladem pravidelná docházka na přednášky.

Language of instruction

Czech

Further Comments

The course is taught annually.
The course is taught: every week.

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