Bi7054 Laboratory Animals in Experimental Biology and Medicine

Faculty of Science
Autumn 2024

The course is not taught in Autumn 2024

Extent and Intensity
2/0/0. 4 credit(s). Type of Completion: zk (examination).
In-person direct teaching
Teacher(s)
RNDr. Jiří Salát, Ph.D. (lecturer)
Guaranteed by
RNDr. Jiří Salát, Ph.D.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: Mgr. et Mgr. Michal Dvořák
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science
Prerequisites
The lectures are suitable for students of biological disciplines interested in research using animal experiments.
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The goal of the course is to gain information about possible use of animals in scientific experiments in agreement with national law.
Learning outcomes
Students will know information about laboratory animals and about experiments on animals. They will gain knowledge about law defining the possible use of animals in experiments.
Syllabus
  • History of animal experiments, System of animal protection in Czech Republic, Ethical and economical aspects of animal experiments, 3R principle;
  • Experimental models: laboratory animals, alternative models, Factors affecting animal welfare, Experimental animals in Czech Republic, Experiments on farm animals and free living animals;
  • Genetics of laboratory animals (inbreeding, congenic strains, GMO strains), SPF a barrier husbandry;
  • Biology and physiology of laboratory animals;
  • Diseases of laboratory animals and diagnostic methods, Zoohygiene;
  • Experimental procedures with laboratory animals (basic manipulation, sampling, administration, anesthesia, euthanasia);
  • Animal models of human diseases, Humanized mice;
  • Law defining the use of animals in experiments;
  • Animal experiment proposal.
Literature
    recommended literature
  • Zákon č. 246/1992 Sb. na ochranu zvířat proti týrání
  • Ochrana, chov a využití pokusných zvířat. Edited by Lukáš Jebavý. Brno: Společnost pro vědu o laboratorních zvířatech, 2014, 454 s. ISBN 9788021324862. info
  • HEDRICH, H.J. The Laboratory Mouse. 2nd ed. Academic Press, 2012. ISBN 978-0-12-382008-2. info
Teaching methods
Lectures with presentation projection.
Assessment methods
Written test and oral exam.
Language of instruction
Czech
Further Comments
Study Materials
The course is taught annually.
The course is taught: every week.
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