PřF:C6880 Biochemistry of Xenobiotics

C6880 Biochemistry of Xenobiotics

Faculty of Science
Spring 2001

Extent and Intensity: 2/0/0. 4 credit(s). Recommended Type of Completion: zk (examination). Other types of completion: k (colloquium).
Teacher(s): RNDr. Miroslav Machala, CSc. (lecturer)
Guaranteed by: RNDr. Miroslav Machala, CSc.
Chemistry Section – Faculty of Science
Contact Person: prof. RNDr. Ladislav Dušek, Ph.D.
Prerequisites: Basic biochemical course.
Course Enrolment Limitations: The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with: there are 10 fields of study the course is directly associated with, display
Course objectives: Classification of xenobiotics. Mechanisms of regulation, effects of xenobiotics. Metabolism of xenobiotics: monooxygenases, conjugating enzymes, MDR. Modes of action of toxicants: receptor-mediated mechanisms, metabolic activation of xenobitics, oxidative stress, inhibition of mitochondrial functions, neurotoxicity, modulation of cytokinetics, disruption of metabolism of endogeneous compounds. Chemical carcinogenesis, chemoprotective compounds.
Language of instruction: Czech
Further Comments: The course is taught annually.
The course is taught: every week.

The course is also listed under the following terms Spring 2000.