PřF:C6880 Biochemistry of Xenobiotics - Course Information

C6880 Biochemistry of Xenobiotics

Extent and Intensity

2/0/0. 4 credit(s). Recommended Type of Completion: zk (examination). Other types of completion: k (colloquium).

Teacher(s)

RNDr. Miroslav Machala, CSc. (lecturer)

Guaranteed by

RNDr. Miroslav Machala, CSc.
Chemistry Section – Faculty of Science
Contact Person: prof. RNDr. Ladislav Dušek, Ph.D.

Prerequisites

Basic biochemical course.

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

• Analytical Chemistry (programme PřF, M-CH)
• Inorganic Chemistry (programme PřF, M-CH)
• Biochemistry (programme PřF, M-CH)
• Ecotoxicology (programme PřF, M-BI)
• Ecotoxicology (programme PřF, N-BI)
• Physical Chemistry (programme PřF, M-CH)
• Chemistry (programme PřF, M-CH)
• Environmental Chemistry (programme PřF, M-CH)
• Macromolecular Chemistry (programme PřF, M-CH)
• Organic Chemistry (programme PřF, M-CH)

Course objectives

Classification of xenobiotics. Mechanisms of regulation, effects of xenobiotics. Metabolism of xenobiotics: monooxygenases, conjugating enzymes, MDR. Modes of action of toxicants: receptor-mediated mechanisms, metabolic activation of xenobitics, oxidative stress, inhibition of mitochondrial functions, neurotoxicity, modulation of cytokinetics, disruption of metabolism of endogeneous compounds. Chemical carcinogenesis, chemoprotective compounds.

Language of instruction

Czech

Further Comments

The course is taught annually.
The course is taught every week.

• Enrolment Statistics (recent)
  
• Permalink: https://is.muni.cz/course/sci/spring2001/C6880