C8858 Biocatalysis

Přírodovědecká fakulta
podzim 2007
Rozsah
2/0. 2 kr. (příf plus uk plus > 4). Ukončení: zk.
Vyučující
prof. RNDr. Zbyněk Prokop, Ph.D. (přednášející)
Garance
prof. RNDr. Zbyněk Prokop, Ph.D.
Národní centrum pro výzkum biomolekul – Přírodovědecká fakulta
Rozvrh
Út 10:00–11:50 C04/211
Předpoklady
- basic course of biochemistry and organic chemistry recommended - course of microbiology and molecular biology helpful
Omezení zápisu do předmětu
Předmět je nabízen i studentům mimo mateřské obory.
Mateřské obory/plány
předmět má 18 mateřských oborů, zobrazit
Cíle předmětu
Biocatalysis is the utilization of natural catalysts, called enzymes, to perform chemical transformations on organic compounds. Biocatalysis is multidisciplinary integration of emerging technologies from life sciences like bioinformatics, protein engineering (rational design and/or in vitro enzyme evolution), medium engineering and immobilization of the biocatalyst for optimum performance and recycling. Biocatalytical application covers the production of fine and bulk chemicals, pharmaceuticals and agrochemicals, environmental application, application in food industry as well as utilisation for analytical processes and diagnostics. The biocatalysis fulfills the concept of sustainable development with minimizing environmental impact (lowering waste production, energy and material consumption). The Biocatalysis course gives basic information about enzyme structure and function, clasification, production and purification of enzymes, enzyme engineering, development of biocatalytical industrial process and outlines the technical and economical potential of enzyme application, giving many examles of industrial processes using enzymes as biocatalyst.
Osnova
  • 1. Opening Lecture 2. Introduction to Enzyme Technology 3. Basics of Enzymes as Biocatalysts 4. Kinetics of Enzyme Catalysed Reaction 5. Principles and Application of Enzyme Selectivity 6. Enzymes in Organic Synthesis I. 7. Enzymes in Organic Synthesis II. 8. Enzyme Production and Purification 9. Engineering of Biocatalysts 10. Immobilization of Enzymes and Cells 11. Reaction Engineering and Process Technology 12. Biotechnology Informatics
Literatura
  • BUCHHOLZ, Klaus, Volker KASCHE a Uwe BORNSCHEUER. Biocatalysts and enzyme technology. Weinheim: Wiley-VCH, 2005, xvii, 448. ISBN 3527304975. info
  • FABER, Kurt. Biotransformations in organic chemistry : a textbook. 5th rev. and corr. ed. Berlin: Springer-Verlag, 2004, xi, 454. ISBN 3540200975. info
Vyučovací jazyk
Angličtina
Informace učitele
http://loschmidt.chemi.muni.cz/peg/
Další komentáře
Předmět je vyučován každoročně.
Předmět je zařazen také v obdobích podzim 2007 - akreditace, podzim 2006, podzim 2008.