PřF:C3181 Biochemistry I - Course Information
C3181 Biochemistry I
Faculty of ScienceAutumn 2011 - acreditation
The information about the term Autumn 2011 - acreditation is not made public
- Extent and Intensity
- 2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
- Teacher(s)
- doc. RNDr. Petr Zbořil, CSc. (lecturer)
- Guaranteed by
- prof. RNDr. Zdeněk Glatz, CSc.
Department of Biochemistry – Chemistry Section – Faculty of Science
Contact Person: prof. RNDr. Vladimír Mikeš, CSc. - Prerequisites
- C2021 Organic Chemistry I || C2700 Basic Organic Chemistry
Basic knowledge of organic and general chemistry, biology - Course Enrolment Limitations
- The course is also offered to the students of the fields other than those the course is directly associated with.
- fields of study / plans the course is directly associated with
- there are 17 fields of study the course is directly associated with, display
- Course objectives
- At the end of the course students should be able to understand and explain - basic properties of natural substances(aminoacids, carbohydrates, lipids, nucleic acids, proteins, enzymes and coenzymes, their properties and structure, active site), thermodynamics, enzyme kinetics, inhibition, allostery, regulation of enzyme acitivity.
- Syllabus
- 1. Aminoacids, properties, determination, chromatography 2. Peptides, peptide bond, primary, secondary, terciary, quaternary structure 3. Non-repetitive structures, colagene, hydropathy, properties of proteins 4. Glycides, properties, reactions, anomers, semiacetals, anomers. conformation 5. Glycosides, oligosaccharides, polysaccharides (starch, glycoge, chitin), heteropolysaccharides. 6. Lipids, acylglycerols, phospholipids, plasmalogens, sphingolipids, steroids 7. Nucleic acids, nucleosides, nucleotides, primary structure 8. DNA, RNA, double-helix, superhelix, denaturation, hybride structure, methods for determination of primary structure 9. Thermodynamics in biochemistry, macroergic bond, reaction kinetics, enzymes, their active site, prosthetic groups, coenzymes, mechanism of enzyme catalysis 10. Coenzymes and vitamins, nicotinamide and NAD, flavins, ATP. AMO, cAMO, biotin, thiamin, coenzyme A, lipoic acid, folic acid 11. Pyridoxalphosphate, B12, metaloporphyrins, iron-sulfur proteins, vitamin C, lipophilic vitamins 12. Michaelis-Menten equation, Km, VL, turnover number, enzyme activity
- Literature
- required literature
- VOET, Donald and Judith G. VOET. Biochemie. Translated by Arnošt Kotyk. 1. vyd. Praha: Victoria Publishing, 1995, S. II-XIV,. ISBN 80-85605-44-9. info
- recommended literature
- VOET, Donald and Judith G. VOET. Biochemistry. 4th ed. Hoboken, N.J.: John Wiley & Sons, 2011, xxv, 1428. ISBN 9780470917459. info
- VODRÁŽKA, Zdeněk. Biochemie. 2., opr. vyd. Praha: Academia, 2002, [506] s. ISBN 9788020006004. info
- Mikeš - Základní pojmy z biochemie II
- LODISH, Harvey F. Molecular cell biology. 6th ed. New York, N.Y.: W.H. Freeman and Company, 2008, xxxvii, 11. ISBN 9780716776017. info
- Teaching methods
- Theoretical lecture 2 hrs a week, supplemented by 1 hr seminar.
- Assessment methods
- Written examination consist usually of 7 questions. Sum of available points usuallly 100. At least 51% of available points required for successful exam.
- Language of instruction
- Czech
- Follow-Up Courses
- Further comments (probably available only in Czech)
- The course can also be completed outside the examination period.
The course is taught annually.
The course is taught: every week. - Listed among pre-requisites of other courses
- C1220 Technologie buněčných kultur
C3181 || C3580 || C5720 - C1230 Technologie buněčných k. -cv
C3181 || C3580 || C5720 - C3180 Biochemistry I - seminar
NOW(C3181) - C3190 Biochemistry I - seminar
NOW(C3181) - C4182 Biochemistry II
C3181 - C4200 Biochemistry II - seminar
C3181 && NOW(C4182) - C4220 Biochemistry - laboratory course
C3181 && (C4221||C1100) - C4230 Biochemistry - laboratory course
C3181 && (C4221||C1100) - C4830 Instrumental Methods in Biochemistry
C3181 || C3580
- C1220 Technologie buněčných kultur
- Enrolment Statistics (Autumn 2011 - acreditation, recent)
- Permalink: https://is.muni.cz/course/sci/autumn2011-acreditation/C3181